What is Lipase Enzyme CAS 9001-62-1?

Lipase, also called triacylglycerol lipase or glycerol ester hydrolase, is a water-soluble biocatalyst that hydrolyzes triglycerides into glycerol and free fatty acids. In non-aqueous media it can also catalyze esterification and transesterification.

What does the enzyme activity specification such as 100,000 U/g mean?

Activity is reported in enzyme units per gram, with one unit defined according to the substrate and assay method. A higher U/g value means a smaller enzyme dose is needed for the same reaction rate, so the product can be customized from about 20,000 to 200,000 U/g depending on the process.

What are the optimum pH and temperature for this lipase?

The listed product works across pH 5.5-9.0 and about 30-50 degrees C. Because lipase sources and immobilization affect the exact optimum, users should run a small activity check at their intended pH, temperature, and substrate before scale-up.

What are the main applications of industrial Lipase?

Key uses include chiral resolution of racemic alcohols, amines, and acids for pharmaceutical intermediates; transesterification of oils and fats into biodiesel; fat and oil hydrolysis; and cleaner enzymatic routes that replace harsh chemical catalysts.

What is the difference between free lipase powder and immobilized lipase?

Free lipase powder is convenient for aqueous batch reactions and can be dosed directly, but is normally used once. Immobilized lipase is bound to a solid support so it can be recovered and reused, and often has better thermal and storage stability in continuous or repeated-batch processes.

Lipase Enzyme (Biocatalyst) CAS 9001-62-1

Lipase Enzyme CAS 9001-62-1 is a versatile hydrolase chemically classified as a triacylglycerol acylhydrolase , functioning primarily as a highly selective biocatalyst for hydrolysis, esterification, and transesterification reactions. Unlike traditional chemical catalysts, this biological macromolecule operates under mild conditions (low temperature and pH) to catalyze the breakdown of fats into glycerol and fatty acids, or conversely, to synthesize complex esters in non-aqueous media. It is extensively utilized in the biodiesel industry for converting waste oils into fuel and in the pharmaceutical sector for the kinetic resolution of chiral intermediates. We provide professional access to this material with competitive factory pricing and the ability to meet customized specifications (such as Immobilized Lipase or Free Powder forms with varying activity U/g) for various manufacturing requirements. Our commitment to technical transparency ensures that every shipment is accompanied by comprehensive MSDS, TDS, COA documentation to support your quality assurance protocols, and we maintain capacity for consistent bulk supply to facilitate large-scale industrial operations.

CAS: 9001-62-1
Synonyms: Lipase, Triacylglycerol lipase, Glycerol ester hydrolase, Fat-splitting enzyme, Lipolytic enzyme, Triglyceride hydrolase, Lipid hydrolase, Lipase enzyme, Biocatalytic lipase
Einecs: 232-619-9
Grade: Industrial / Biocatalytic Grade
Package: 25kg Fiber Drum (with inner PE bag) / 1kg Aluminum Foil Bag

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Product Description

1 Physicochemical Properties & Specification

2 Key Applications

3 Quality Assurance (QA/QC)

4 Storage, Handling & Safety

5 Logistics & Shipping

Physicochemical Properties & Specification

Standard: National Standard GB/T 23535-2009 & Enterprise Internal Control

Test Item	Specification
Appearance	White to yellowish powder or granule
Enzyme Activity	≥100,000extU/g (Customizable: 20k-200k)
Moisture (Loss on Drying)	≤8.0%
Optimum pH Range	5.5−9.0
Optimum Temperature	30∘extC−50∘extC
Bulk Density	0.50−0.70extg/mL
Heavy Metals (as Pb)	≤30extmg/kg
Arsenic (As)	≤3extmg/kg
Solubility	Soluble in water; Insoluble in organic solvents

Key Applications

Our Catalyst Lipase is engineered to replace harsh chemical catalysts, offering lower energy consumption and reduced by-product formation in the following sectors:

1. Pharmaceutical Synthesis (Chiral Resolution) Used extensively for the kinetic resolution of racemic alcohols, amines, and acids. It is a critical tool in the synthesis of chiral drug intermediates (APIs), including anti-inflammatory and cardiovascular medications, ensuring high enantiomeric excess (ee%).

2. Biodiesel & Bio-Energy Facilitates the transesterification of oils and fats (triglycerides) into fatty acid methyl esters (biodiesel). Enzymatic catalysis avoids soap formation common in alkaline processes and allows for the processing of high-acid value feedstocks like waste cooking oil.

3. Fine Chemical Manufacturing

Esterification: Synthesis of specialty esters, flavors, and fragrances (e.g., ethyl hexanoate).
Polymer Modification: Used in the modification of polyester resins to improve biodegradability.

4. Paper & Pulp Industry (Pitch Control) Hydrolyzes triglycerides in wood resin (pitch) during the pulping process, preventing pitch deposition on machinery and improving paper quality.

Quality Assurance (QA/QC)

We maintain a pharmaceutical-grade quality management system to ensure the stability and activity of our biological enzymes.

Activity Assay: Every batch is tested using the standard Titration Method (or Spectrophotometry upon request) to guarantee the catalytic unit count per gram meets the Certificate of Analysis (COA).
Microbial Control: Rigorous testing for microbial limits, ensuring the absence of pathogens such as Salmonella, E. coli, and Staphylococcus aureus, complying with ISO standards.
Consistency: We utilize automated fermentation control systems to minimize batch-to-batch variation, ensuring consistent reaction kinetics for your industrial processes.

Storage, Handling & Safety

Storage Conditions Enzymes are biologically active proteins and can lose activity if stored improperly.

Temperature: Recommended storage at $2^{\circ} e x t C - 8^{\circ} e x t C$ 2∘extC−8∘extC (Refrigerated). Can be stored at room temperature ( $< 25^{\circ} e x t C$ <25∘extC) for short periods (up to 3 months) with minimal activity loss.
Environment: Keep in a dry, dark place. Seal tightly after use to prevent moisture absorption.
Shelf Life: 12 months under recommended conditions (Activity loss $< 10 %$ <10%).

Safety Instructions (PPE) Inhalation of enzyme dust/mist may induce sensitization and cause allergic type reactions in sensitized individuals.

Respiratory Protection: Crucial. Wear a NIOSH/MSHA approved dust mask or respirator (N95) when handling powder.
Eye/Skin Protection: Wear safety glasses and protective gloves to avoid prolonged contact.
First Aid: If inhaled, remove to fresh air. If on skin/eyes, wash thoroughly with water.

Logistics & Shipping

Cold Chain Option: For bulk orders or long transit times, we offer Reefer Container shipping or thermal-insulated packaging with ice packs to maintain enzyme activity.
Port of Loading: Shanghai Air/Sea Port (Priority for biologicals).
Lead Time: 5-7 working days.
Documents: Non-Hazardous Chemical Certification, COA, MSDS, and Origin Certificate provided.

Looking for high-efficiency biocatalysts? Upgrade your synthesis process with our premium Lipase.

📧 Email: info@industrochem.com

FAQ - Technical & Supply Chain

Q:
What is Lipase Enzyme CAS 9001-62-1?

A: Lipase, also called triacylglycerol lipase or glycerol ester hydrolase, is a water-soluble biocatalyst that hydrolyzes triglycerides into glycerol and free fatty acids. In non-aqueous media it can also catalyze esterification and transesterification.
Q:
What does the enzyme activity specification such as 100,000 U/g mean?

A: Activity is reported in enzyme units per gram, with one unit defined according to the substrate and assay method. A higher U/g value means a smaller enzyme dose is needed for the same reaction rate, so the product can be customized from about 20,000 to 200,000 U/g depending on the process.
Q:
What are the optimum pH and temperature for this lipase?

A: The listed product works across pH 5.5-9.0 and about 30-50 degrees C. Because lipase sources and immobilization affect the exact optimum, users should run a small activity check at their intended pH, temperature, and substrate before scale-up.
Q:
What are the main applications of industrial Lipase?

A: Key uses include chiral resolution of racemic alcohols, amines, and acids for pharmaceutical intermediates; transesterification of oils and fats into biodiesel; fat and oil hydrolysis; and cleaner enzymatic routes that replace harsh chemical catalysts.
Q:
What is the difference between free lipase powder and immobilized lipase?

A: Free lipase powder is convenient for aqueous batch reactions and can be dosed directly, but is normally used once. Immobilized lipase is bound to a solid support so it can be recovered and reused, and often has better thermal and storage stability in continuous or repeated-batch processes.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

COA, TDS, SDS/MSDS and packing details are available on request.

Quotation

Send the CAS number, grade, quantity, packing preference and destination.

Sample & Supply

Support is available for samples, trial orders, bulk and repeat supply.

Storage & Shipping

Product-specific conditions are confirmed before order.

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