Calcium Glycerophosphate CAS 27214-00-2

Physical & Chemical Properties

Calcium Glycerophosphate is a white or slightly yellowish crystalline powder. Its key advantage over other calcium salts is its solubility profile and amphoteric nature, making it versatile in various pH environments.

Key Application Fields

1. Advanced Oral Care (Toothpaste & Mouthwash)

This is the highest-value application for CAS 27214-00-2.

• Plaque Fighter: It helps neutralize the acidic environment in the mouth, which is the primary cause of tooth decay.
• Remineralization: It provides both Calcium and Phosphate ions—the building blocks of enamel. It acts synergistically with fluoride to strengthen teeth more effectively than fluoride alone.
• Sensitivity: It is a key ingredient in “desensitizing” toothpastes.

2. Dietary Supplements & Infant Nutrition

• Bioavailability: Unlike Calcium Carbonate, which requires strong stomach acid to break down, Calcium Glycerophosphate is more easily absorbed by the body.
• Digestive Comfort: It is less likely to cause gas, bloating, or constipation, making it ideal for premium supplement lines targeting sensitive consumers or infants (often used in formula fortification).

3. Food Fortification

Because it is odorless and has a relatively neutral taste profile compared to other calcium salts, it does not alter the flavor of fortified beverages, yogurts, or baked goods.

Safety and Precautionary Measures

Although Calcium Glycerophosphate is widely recognized as safe (GRAS in many jurisdictions) for consumption, handling the raw chemical requires standard industrial safety protocols.

• Inhalation: The powder can be fine. Inhalation may cause respiratory tract irritation. Workers should use N95 dust masks during weighing and mixing.
• Eye Contact: Mechanical irritation is possible. Safety goggles are mandatory in the blending area.
• Ingestion: While safe in food dosages, accidental ingestion of large, concentrated quantities should be managed by drinking water and seeking medical advice.

Storage and Handling Conditions

Proper storage is critical to maintaining the material’s flowability and preventing microbial growth.

1. Moisture Sensitivity: The product is slightly hygroscopic (absorbs moisture from the air). If left open, it can clump, which causes issues in automated feeders.
2. Environment: Store in a cool, dry, and well-ventilated warehouse. Temperature should ideally be below 25°C.
3. Packaging: Standard export packaging from Chinese factories is usually 25kg fiber drums or kraft paper bags with double PE liners. The fiber drum is recommended for ocean transport to prevent compression and moisture ingress.
4. Shelf Life: Typically 24 months when stored in original, unopened packaging.