What is Caffeic Acid Powder CAS 331-39-5?

Caffeic Acid Powder CAS 331-39-5 is 3,4-dihydroxycinnamic acid, a naturally occurring hydroxycinnamic acid with molecular formula C₉H₈O₄ and a molecular weight of about 180.16 g/mol. It is supplied as a high-purity phenolic acid powder for pharmaceutical, food, nutraceutical and cosmetic applications.

Is caffeic acid the same as caffeine?

No. Caffeic acid is a phenolic acid found in coffee and many plants, while caffeine is a different alkaloid compound. The similar spelling comes from their shared occurrence in coffee, not from a common chemical structure or function.

What are the main uses of Caffeic Acid Powder CAS 331-39-5?

It is used as a fine-chemical intermediate, notably for synthesizing derivatives such as caffeic acid phenethyl ester, and as an antioxidant or anti-inflammatory active in research and formulation. Common downstream fields include pharmaceutical synthesis, functional foods, dietary supplements and personal-care products.

What is the solubility of caffeic acid in water and organic solvents?

Caffeic acid is sparingly soluble in cold water but becomes more soluble in hot water. It also dissolves readily in polar organic solvents such as ethanol, which is useful for cosmetic, analytical and synthetic work.

What key specifications should be checked for Caffeic Acid Powder?

Confirm appearance, HPLC assay, melting range, loss on drying, residue on ignition, heavy metals and related impurities. Select pharmaceutical, food or cosmetic grade as required and request the batch-specific analysis before formulation or scale-up.

How should Caffeic Acid Powder CAS 331-39-5 be stored and handled?

Store it in tightly closed, light-protected containers in a cool, dry environment away from strong oxidizers and direct sunlight. Use powder-handling controls and suitable PPE during weighing, transfer and processing.

Caffeic Acid Powder CAS 331-39-5

Caffeic Acid (3,4-dihydroxycinnamic acid), CAS 331-39-5, is a naturally occurring phenolic-acid antioxidant supplied for pharmaceutical, food, nutraceutical and cosmetic applications. Confirm the required purity and grade, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 331-39-5
Synonyms: 3,4-Dihydroxycinnamic acid, 3,4-Dihydroxy-trans-cinnamic acid, trans-Caffeic acid
Einecs: 206-361-2
Molecular Formula: C₉H₈O₄
Grade: Pharmaceutical / Food / Cosmetic grade, typical purity ≥98% (HPLC), higher grades available on request
Package: 1 kg aluminum foil bag; 25 kg fiber drum with double PE liner or customized industrial packing

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Product Description

Caffeic Acid, CAS 331-39-5, also known as 3,4-dihydroxycinnamic acid, is a naturally occurring hydroxycinnamic (phenolic) acid; the EC/EINECS number is 206-361-2.

Synonyms: 3,4-Dihydroxycinnamic acid; 3,4-Dihydroxy-trans-cinnamic acid; trans-Caffeic acid.

CAS: 331-39-5.

Molecular formula: C₉H₈O₄.

Molecular weight: 180.16.

EC number: 206-361-2.

It is a light-yellow to yellow-tan crystalline powder with a melting point of about 223–225 °C (decomposition).

It is sparingly soluble in cold water and soluble in hot water; it is soluble in ethanol (about 50 mg/mL) and other polar organic solvents.

The predicted pKa of the phenolic group is about 4.6 and the estimated log P (octanol/water) is about 1.2.

It is used as a natural antioxidant in nutraceuticals, functional foods and dietary supplements, often combined with other polyphenols such as chlorogenic acid or ferulic acid.

It is used in pharmaceutical and biomedical research as an intermediate and reference standard, and is investigated for antioxidant, anti-inflammatory, cardiovascular and neuroprotective effects.

It is used in skin-care, sunscreen and anti-aging formulas as a natural antioxidant, and in oils, fats and processed foods to inhibit lipid oxidation and extend shelf life.

Confirm purity (typically ≥98% by HPLC), appearance, melting range, related impurities, loss on drying, residue on ignition, heavy metals and color stability; pharmaceutical, food and cosmetic grades are available.

Store in tightly closed, light-resistant containers in a cool, dry place, preferably at 2–8 °C, away from strong oxidizing agents and bases; the powder is combustible and air/light sensitive, so use dust control and suitable PPE.

Confirm the current product-specific specification.

Confirm packaging with the requested quantity and destination requirements.

Document requirements should be confirmed from the current specification, SDS, COA or other product-specific files.

The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.

For an RFQ, state the intended use, required specification, quantity, packaging, destination and document needs.

FAQ - Technical & Supply Chain

Q:
What is Caffeic Acid Powder CAS 331-39-5?

A: Caffeic Acid Powder CAS 331-39-5 is 3,4-dihydroxycinnamic acid, a naturally occurring hydroxycinnamic acid with molecular formula C₉H₈O₄ and a molecular weight of about 180.16 g/mol. It is supplied as a high-purity phenolic acid powder for pharmaceutical, food, nutraceutical and cosmetic applications.
Q:
Is caffeic acid the same as caffeine?

A: No. Caffeic acid is a phenolic acid found in coffee and many plants, while caffeine is a different alkaloid compound. The similar spelling comes from their shared occurrence in coffee, not from a common chemical structure or function.
Q:
What are the main uses of Caffeic Acid Powder CAS 331-39-5?

A: It is used as a fine-chemical intermediate, notably for synthesizing derivatives such as caffeic acid phenethyl ester, and as an antioxidant or anti-inflammatory active in research and formulation. Common downstream fields include pharmaceutical synthesis, functional foods, dietary supplements and personal-care products.
Q:
What is the solubility of caffeic acid in water and organic solvents?

A: Caffeic acid is sparingly soluble in cold water but becomes more soluble in hot water. It also dissolves readily in polar organic solvents such as ethanol, which is useful for cosmetic, analytical and synthetic work.
Q:
What key specifications should be checked for Caffeic Acid Powder?

A: Confirm appearance, HPLC assay, melting range, loss on drying, residue on ignition, heavy metals and related impurities. Select pharmaceutical, food or cosmetic grade as required and request the batch-specific analysis before formulation or scale-up.
Q:
How should Caffeic Acid Powder CAS 331-39-5 be stored and handled?

A: Store it in tightly closed, light-protected containers in a cool, dry environment away from strong oxidizers and direct sunlight. Use powder-handling controls and suitable PPE during weighing, transfer and processing.

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