What is Kojic Acid Dipalmitate CAS 79725-98-7?

Kojic Acid Dipalmitate CAS 79725-98-7 is a diester derivative of kojic acid, with the molecular formula C38H66O6. It is an oil-soluble cosmetic active used mainly in skin-brightening formulations.

How does it differ from standard Kojic Acid?

The two active hydroxyl groups are esterified with palmitic acid, making the molecule more lipophilic and less prone to oxidation, color change and metal-ion complexation than kojic acid. This gives better compatibility with oils, esters, sunscreens and preservatives.

How does Kojic Acid Dipalmitate work in skin-lightening products?

It inhibits tyrosinase and helps reduce melanin formation. In cosmetic use it is intended for creams, lotions, serums and other leave-on formulas targeting uneven tone, dark spots or hyperpigmentation.

What are the key quality parameters?

Common specifications are white to off-white crystalline powder, HPLC assay at least 99%, melting point 92-96 C, loss on drying, residue on ignition, controlled heavy metals and arsenic, and low color in solution.

How should Kojic Acid Dipalmitate be stored?

Store it sealed in a cool, dry place away from light and moisture. Because it is oil-soluble and heat/light stable compared with kojic acid, it should still be protected from prolonged high temperature during storage and handling.

Kojic Acid Dipalmitate CAS 79725-98-7

Kojic Acid Dipalmitate (CAS 79725-98-7) is a highly stable, oil-soluble derivative of Kojic Acid utilizing its modified ester structure to provide superior skin whitening efficacy without the oxidation issues of the parent compound. Chemically identified as the diester of Kojic Acid and Palmitic Acid, this white crystalline powder functions as a potent tyrosinase inhibitor, effectively blocking melanin formation to treat hyperpigmentation, age spots, and melasma. Unlike pure Kojic Acid, KAD is resistant to light, heat, and metallic ions, preventing color changes in formulations. As a lipophilic Cosmetic active, it is extensively integrated into high-end brightening creams, lotions, and sun-repair products due to its excellent skin permeability and moisturizing properties. We ensure bulk supply capabilities for this material, providing access to competitive factory pricing and customized specifications to meet specific melting point and color standards. Full technical documentation, including MSDS, TDS, COA, is available to support compliance and safety protocols.

CAS: 79725-98-7
Synonyms: KAD, Kojic Dipalmitate, 2-Palmitoyloxymethyl-5-palmitoyloxy-gamma-pyrone, [6-(Palmitoyloxymethyl)-4-oxo-4H-pyran-3-yl] palmitate, Diepalmitate of Kojic Acid
Molecular Formula: C38H66O6
Grade: Cosmetic Grade
Package: 1kg/Aluminium foil bag; 25kg/Fiber drum (or customized)

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Product Description

Kojic Acid Dipalmitate (KAD) is a modified ester derivative of Kojic Acid. It overcomes the instability of Kojic Acid to light, heat, and metal ions, and keeps the inhibitory activity of tyrosinase and prevents the forming of melanin.

As a fat-soluble skin whitening agent, it is easier to be absorbed by the skin compared to water-soluble acids. It is compatible with almost all kinds of preservatives and sunscreens, making it a versatile ingredient for various cosmetic formulations.

Key Benefits:

Skin Lightening: Effectively inhibits tyrosinase activity.
Stability: Chemically stable, does not change color over time compared to pure Kojic Acid.
Solubility: Oil-soluble, making it easy to formulate into creams and lotions.

1 Physicochemical Properties

2 Applications

3 Storage Conditions

4 Safety Precautions

Physicochemical Properties

Parameter	Specification (Standard)
Appearance	White to off-white crystalline powder
Assay (HPLC)	≥ 99.0%
Melting Point	92.0°C – 96.0°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (Pb)	≤ 10 ppm
Arsenic (As)	≤ 2 ppm
Color (10% solution)	≤ 30 Hazen
Solubility	Soluble in oil, alcohol; Insoluble in water

Applications

Kojic Acid Dipalmitate is widely used in the cosmetic and personal care industry. Recommended dosage is typically 1.0% ~ 5.0%.

Skin Whitening Products: Used in face creams, serums, and lotions to reduce hyperpigmentation, melasma, and age spots.
Sun Care: Added to sunscreen products to prevent tanning and sun-induced pigmentation.
Anti-Aging: Used in formulations to brighten skin tone and improve overall complexion.
Color Cosmetics: Incorporated into foundations and concealers for dual makeup and skincare benefits.

Storage Conditions

Storage: Store in a cool, dry, and well-ventilated place.
Container: Keep the container tightly closed.
Protection: Protect from direct sunlight, heat, and moisture.
Shelf Life: 24 months when stored properly in original sealed packaging.

Safety Precautions

Handling: Avoid direct contact with skin and eyes. Wear appropriate protective gloves, goggles, and a dust mask during handling.
In Case of Contact:
- Eyes: Rinse cautiously with water for several minutes.
- Skin: Wash with plenty of soap and water.
Disposal: Dispose of contents/container in accordance with local regulations.
Note: For external use only. Not for internal consumption.

FAQ - Technical & Supply Chain

Q:
What is Kojic Acid Dipalmitate CAS 79725-98-7?

A: Kojic Acid Dipalmitate CAS 79725-98-7 is a diester derivative of kojic acid, with the molecular formula C38H66O6. It is an oil-soluble cosmetic active used mainly in skin-brightening formulations.
Q:
How does it differ from standard Kojic Acid?

A: The two active hydroxyl groups are esterified with palmitic acid, making the molecule more lipophilic and less prone to oxidation, color change and metal-ion complexation than kojic acid. This gives better compatibility with oils, esters, sunscreens and preservatives.
Q:
How does Kojic Acid Dipalmitate work in skin-lightening products?

A: It inhibits tyrosinase and helps reduce melanin formation. In cosmetic use it is intended for creams, lotions, serums and other leave-on formulas targeting uneven tone, dark spots or hyperpigmentation.
Q:
What are the key quality parameters?

A: Common specifications are white to off-white crystalline powder, HPLC assay at least 99%, melting point 92-96 C, loss on drying, residue on ignition, controlled heavy metals and arsenic, and low color in solution.
Q:
How should Kojic Acid Dipalmitate be stored?

A: Store it sealed in a cool, dry place away from light and moisture. Because it is oil-soluble and heat/light stable compared with kojic acid, it should still be protected from prolonged high temperature during storage and handling.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

COA, TDS, SDS/MSDS and packing details are available on request.

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Send the CAS number, grade, quantity, packing preference and destination.

Sample & Supply

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Storage & Shipping

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