What is Tranexamic Acid CAS 1197-18-8?

Tranexamic Acid CAS 1197-18-8 is a synthetic amino acid derivative with the molecular formula C8H15NO2 and molecular weight 157.21 g/mol. It is supplied as the trans-isomer and is widely used in pharmaceutical and cosmetic applications.

Is the supplied Tranexamic Acid the active trans-isomer?

Yes. CAS 1197-18-8 identifies trans-4-(aminomethyl)cyclohexanecarboxylic acid, the biologically active isomer used for both pharmaceutical hemostatic action and cosmetic hyperpigmentation management.

How does Tranexamic Acid work in skin-brightening cosmetics?

It interferes with the plasminogen/plasmin pathway and related inflammatory signals that can activate melanocytes after UV or skin stress. This helps reduce melanin overproduction, so it is commonly used in serums, creams and spot-treatment formulas for melasma and uneven pigmentation.

What are the main quality parameters for this product?

Typical export specifications are white crystalline powder, assay 99.0-101.0% on dried basis, IR identification, pH 7.0-8.0, loss on drying, residue on ignition and controlled heavy metals. It is freely soluble in water and practically insoluble in ethanol and acetone.

How should Tranexamic Acid be stored?

Store it in a tightly sealed container in a cool, dry place, protected from light and moisture. For formulation, use a water-based or aqueous-phase system at a pH appropriate for the finished product.

Tranexamic Acid CAS 1197-18-8

Tranexamic Acid, CAS 1197-18-8, also known as TXA, is a synthetic amino acid derivative supplied for skin-brightening cosmetics and pharmaceutical hemostatic applications. Confirm the required grade and specification, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 1197-18-8
Synonyms: TXA, Trans-4-(Aminomethyl)cyclohexanecarboxylic acid, Trans-AMCHA, 4-(Aminomethyl)cyclohexane-1-carboxylic acid
Einecs: 214-818-2
Molecular Formula: C₈H₁₅NO₂
Grade: Cosmetic Grade / Pharma Grade (BP/USP/JP Standards)
Package: 25kg/Fiber Drum with double PE inner bag; or 1kg/Aluminium Foil Bag.

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Product Description

Tranexamic Acid, CAS 1197-18-8, also called TXA, is a synthetic amino acid derivative.

Synonyms: TXA; Trans-4-(Aminomethyl)cyclohexanecarboxylic acid; Trans-AMCHA; 4-(Aminomethyl)cyclohexane-1-carboxylic acid.

CAS: 1197-18-8.

It has the molecular formula C8H15NO2 and molecular weight 157.21 g/mol.

It appears as a white crystalline powder.

It has an assay of 99.0–101.0% on a dried basis and a pH of about 7.0–8.0 in a 5% solution.

It is freely soluble in water and practically insoluble in ethanol and acetone.

It is stable to light, heat and oxidation, unlike many other whitening agents.

It inhibits the plasminogen activator pathway that triggers melanin production from UV damage.

It is used to reduce melasma, dark spots and hyperpigmentation.

It has anti-inflammatory properties and soothes skin redness.

It is used in lotions, creams, serums, face masks and spot correctors, typically at 0.5–3.0%.

It is often combined with niacinamide or vitamin C for enhanced effects.

It is used as a hemostatic antifibrinolytic agent in surgery, trauma and heavy menstruation.

Confirm appearance, assay, identification, pH, loss on drying, residue on ignition, heavy metals, chloride, sulfate, related substances and solubility.

Store in a tightly sealed container in a cool, dry place, protected from light and moisture.

Confirm packaging with the requested quantity and destination requirements.

The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.

For an RFQ, state the intended use, required grade and specification, quantity, packaging, destination and document needs.

FAQ - Technical & Supply Chain

Q:
What is Tranexamic Acid CAS 1197-18-8?

A: Tranexamic Acid CAS 1197-18-8 is a synthetic amino acid derivative with the molecular formula C8H15NO2 and molecular weight 157.21 g/mol. It is supplied as the trans-isomer and is widely used in pharmaceutical and cosmetic applications.
Q:
Is the supplied Tranexamic Acid the active trans-isomer?

A: Yes. CAS 1197-18-8 identifies trans-4-(aminomethyl)cyclohexanecarboxylic acid, the biologically active isomer used for both pharmaceutical hemostatic action and cosmetic hyperpigmentation management.
Q:
How does Tranexamic Acid work in skin-brightening cosmetics?

A: It interferes with the plasminogen/plasmin pathway and related inflammatory signals that can activate melanocytes after UV or skin stress. This helps reduce melanin overproduction, so it is commonly used in serums, creams and spot-treatment formulas for melasma and uneven pigmentation.
Q:
What are the main quality parameters for this product?

A: Typical export specifications are white crystalline powder, assay 99.0-101.0% on dried basis, IR identification, pH 7.0-8.0, loss on drying, residue on ignition and controlled heavy metals. It is freely soluble in water and practically insoluble in ethanol and acetone.
Q:
How should Tranexamic Acid be stored?

A: Store it in a tightly sealed container in a cool, dry place, protected from light and moisture. For formulation, use a water-based or aqueous-phase system at a pH appropriate for the finished product.

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