Language

Current Language
    Change Language
    HomeProductsDaily ChemicalsCosmetic Raw MaterialsTranexamic CAS 1197-18-8
    • Tranexamic CAS 1197-18-8

    Tranexamic CAS 1197-18-8

    Tranexamic Acid (CAS 1197-18-8) is a synthetic derivative of the amino acid lysine, functioning as a premier antifibrinolytic agent in pharmaceuticals and a highly effective skin brightening ingredient in cosmetics. Chemically identified as trans-4-(Aminomethyl)cyclohexanecarboxylic acid, this white crystalline powder acts to competitively inhibit the activation of plasminogen to plasmin, thereby preventing blood clot breakdown and reducing inflammatory pigmentation pathways. As a water-soluble Trans-isomer amino acid, it is extensively integrated into hemostatic medications for trauma care and into advanced dermatological formulations to treat melasma, dark spots, and redness. We ensure bulk supply capabilities for this material, providing access to competitive factory pricing and customized specifications to meet specific purity standards (e.g., BP/USP/EP grades). Full technical documentation, including MSDS, TDS, COA, is available to support compliance and safety protocols.

    • CAS: 1197-18-8
    • Synonyms: TXA, Trans-4-(Aminomethyl)cyclohexanecarboxylic acid, Trans-AMCHA, 4-(Aminomethyl)cyclohexane-1-carboxylic acid
    • Einecs: 214-818-2
    • Molecular Formula: C8H15NO2
    • Grade: Cosmetic Grade / Pharma Grade (BP/USP/JP Standards)
    • Package: 25kg/Fiber Drum with double PE inner bag; or 1kg/Aluminium Foil Bag.
    Request a quote
    Share:

    Product Description

    Tranexamic Acid is a synthetic amino acid derivative that serves as a powerful active ingredient in both the pharmaceutical and cosmetic industries. While originally used as a hemostatic agent, it has gained global recognition as a premier skin whitening and anti-pigmentation agent.

    Our Tranexamic Acid is a high-purity, white crystalline powder that is water-soluble and highly stable against light, heat, and oxidation, making it superior to unstable whitening agents like Vitamin C. It works by inhibiting the activity of plasminogen activator, effectively blocking the pathway that triggers melanin production caused by UV damage. It is clinically proven to reduce melasma, dark spots, and hyperpigmentation while also possessing anti-inflammatory properties to soothe skin redness.

    1 Physicochemical Properties
    2 Applications
    3 Storage Conditions
    4 Safety Precautions

    Physicochemical Properties

    The following specifications are based on our standard export quality (Cosmetic/Pharma Grade):

    Test ItemSpecification (Standard: BP/USP/JP)
    AppearanceWhite crystalline powder
    Assay (Purity)99.0% – 101.0% (Calculated on dried basis)
    Identification (IR)Conforms to structure
    pH Value (5% Solution)7.0 – 8.0
    Loss on Drying≤ 0.5%
    Residue on Ignition (Ash)≤ 0.1%
    Heavy Metals≤ 10 ppm
    Chloride (Cl)≤ 0.014%
    Sulphate (SO4)≤ 0.014%
    Related SubstancesChromatographic Purity (HPLC) < 0.2%
    SolubilityFreely soluble in water and glacial acetic acid

    Applications

    Tranexamic Acid CAS 1197-18-8 is widely utilized in the following sectors:

    1. Cosmetics & Skincare (Primary Focus):
      • Whitening & Brightening: Effectively treats melasma, freckles, and age spots by inhibiting melanin synthesis.
      • Anti-Inflammatory: Reduces redness and skin irritation, suitable for sensitive skin products.
      • Synergy: Often combined with Niacinamide or Vitamin C for enhanced effects.
      • Product Types: Used in lotions, creams, serums, face masks, and spot correctors.
      • Recommended Dosage: 0.5% – 3.0% in cosmetic formulations.
    2. Pharmaceuticals:
      • Hemostatic Agent: Used to control bleeding in surgery, trauma, and heavy menstruation (antifibrinolytic).
      • Oral & Injectable: Manufactured to meet BP/USP pharmacopeia standards for medical use.

    Storage Conditions

    • Environment: Store in a cool, dry, and well-ventilated area.
    • Temperature: Stable at room temperature.
    • Container: Keep the container tightly closed.
    • Stability: Unlike many other whitening agents, Tranexamic Acid is stable to light and heat, meaning it does not require brown bottles or refrigeration during transport, and maintains potency in finished formulations.
    • Shelf Life: 36 months (3 Years) from the date of manufacture.

    Safety Precautions

    • Handling: Wear appropriate protective clothing, gloves, and eye/face protection. Avoid breathing dust.
    • Skin Compatibility: It is generally considered non-irritating and safe for topical application on skin at recommended dosages.
    • Eye Contact: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    • Ingestion: Harmful if swallowed in large quantities (pure powder).
    • Disposal: Dispose of contents/container in accordance with local/regional regulations.

    FAQ - Technical & Supply Chain

    • Q:

      How does Tranexamic Acid CAS 1197-18-8 function in cosmetic skin lightening?

      A: Tranexamic Acid (CAS 1197-18-8) functions by inhibiting the interaction between keratinocytes and melanocytes. It blocks the plasmin pathway, which reduces the release of inflammatory mediators (like arachidonic acid and prostaglandins) that trigger melanin production, making it particularly effective for treating UV-induced hyperpigmentation and melasma.
    • Q:

      Is this product supplied in the biologically active trans-isomer form?

      A: Yes, our supply strictly conforms to the CAS 1197-18-8 specification for the trans-isomer, which is the biologically active form required for both pharmaceutical efficacy and cosmetic safety; the cis-isomer is inactive and typically removed.
    Documents

    Documents and Product Support

    For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.

    • COA for batch-based quality reference
    • TDS for key physical and chemical information
    • SDS / MSDS for handling, storage, and safety reference
    • Packing information for sample, trial, and bulk orders
    • Technical communication based on application and specification requirements
    Quotation

    Information to Confirm Before Quotation

    Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.

    • Product name and CAS number
    • Application or intended end use
    • Required purity, grade, or specification
    • Sample quantity, trial order, or bulk demand
    • Preferred packing form or net weight
    • Destination country or port
    • Required documents or compliance expectations
    Storage & Handling

    Packaging, Storage, and Handling Notes

    Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.

    Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.

    Supply Support

    Sample, Bulk Order and Repeat Supply Support

    Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.

    For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.

    Contact Form

    Use our contact form to send us your questions, suggestions or comments. We will respond as soon as possible.

    Product Categories

    Tags:

    Amino Acid Derivative Cosmetic Active Ingredient Pharmaceutical Ingredient Skin Brightening Ingredient

    Related Products