What is p-Hydroxyacetophenone CAS 99-93-4?

p-Hydroxyacetophenone CAS 99-93-4 is an aromatic ketone with the molecular formula C8H8O2 and molecular weight 136.15 g/mol. It is also called 4'-hydroxyacetophenone or P-HAP and is used in cosmetics and organic synthesis.

How is Hydroxyacetophenone used in cosmetic preservation?

It is used as a multifunctional cosmetic ingredient and preservation booster. It has weak antimicrobial activity on its own, so it is normally combined with a suitable preservative system rather than used as the sole preservative.

Why is p-Hydroxyacetophenone described as an antioxidant?

The material can function as an antioxidant ingredient in cosmetic formulations, helping protect oil-soluble components from oxidative degradation. It is also compatible with many emulsion, serum and mask systems.

What are typical physical specifications for this product?

It is generally a white to off-white crystalline powder with a melting point around 108-111 C, HPLC purity of about 99% or higher, low loss on drying and controlled ash and heavy-metal content. It is soluble in ethanol and some other organic solvents.

What other applications are relevant to CAS 99-93-4?

p-Hydroxyacetophenone is also used as an intermediate in pharmaceutical and fine-chemical synthesis and can be used in fragrance compositions. The appropriate grade depends on whether the final use is cosmetic, pharmaceutical, or industrial.

p-Hydroxyacetophenone CAS 99-93-4

p-Hydroxyacetophenone, CAS 99-93-4, also known as 4’-hydroxyacetophenone or P-HAP, is an aromatic ketone supplied as a cosmetic preservative booster, antioxidant and skin-soothing ingredient, and as a pharmaceutical intermediate. Confirm the required grade and specification, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 99-93-4
Synonyms: 4'-Hydroxyacetophenone, 1-(4-Hydroxyphenyl)ethanone, p-Acetylphenol, P-HAP, 4-Acetylphenol
Einecs: 202-802-8
Molecular Formula: C₈H₈O₂
Grade: Cosmetic Grade / Pharma Intermediates
Package: 25kg/Cardboard Drum with double PE inner lining

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Product Description

p-Hydroxyacetophenone, CAS 99-93-4, also called 4’-hydroxyacetophenone or P-HAP, is an aromatic ketone.

Synonyms: 4’-Hydroxyacetophenone; 1-(4-Hydroxyphenyl)ethanone; p-Acetylphenol; P-HAP; 4-Acetylphenol.

CAS: 99-93-4.

It has the molecular formula C8H8O2 and molecular weight 136.15 g/mol.

It appears as white needle-like crystals or powder.

It has an assay of not less than 99.0% and a melting point of about 107–111 °C.

It is soluble in ethanol, propylene glycol and warm water but only slightly soluble in cold water.

It is used as a multifunctional cosmetic ingredient and preservative booster.

It has weak antimicrobial activity on its own and is normally combined with a preservative system.

It can function as an antioxidant in cosmetic formulations, protecting oil-soluble components.

It provides anti-irritant and skin-soothing benefits for sensitive-skin formulations.

It is used in facial masks, sensitive-skin lotions, anti-aging creams, shampoos and wet wipes.

It is used as a pharmaceutical intermediate, including in the synthesis of atenolol.

It is used as an intermediate for flavors, fragrances and agrochemicals.

Confirm appearance, assay, melting point, loss on drying, residue on ignition, heavy metals, iron, color, solubility and solution clarity.

Store in a cool, dry, well-ventilated warehouse away from high heat and direct sunlight, and keep containers tightly sealed.

Confirm packaging with the requested quantity and destination requirements.

The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.

For an RFQ, state the intended use, required grade and specification, quantity, packaging, destination and document needs.

FAQ - Technical & Supply Chain

Q:
What is p-Hydroxyacetophenone CAS 99-93-4?

A: p-Hydroxyacetophenone CAS 99-93-4 is an aromatic ketone with the molecular formula C8H8O2 and molecular weight 136.15 g/mol. It is also called 4'-hydroxyacetophenone or P-HAP and is used in cosmetics and organic synthesis.
Q:
How is Hydroxyacetophenone used in cosmetic preservation?

A: It is used as a multifunctional cosmetic ingredient and preservation booster. It has weak antimicrobial activity on its own, so it is normally combined with a suitable preservative system rather than used as the sole preservative.
Q:
Why is p-Hydroxyacetophenone described as an antioxidant?

A: The material can function as an antioxidant ingredient in cosmetic formulations, helping protect oil-soluble components from oxidative degradation. It is also compatible with many emulsion, serum and mask systems.
Q:
What are typical physical specifications for this product?

A: It is generally a white to off-white crystalline powder with a melting point around 108-111 C, HPLC purity of about 99% or higher, low loss on drying and controlled ash and heavy-metal content. It is soluble in ethanol and some other organic solvents.
Q:
What other applications are relevant to CAS 99-93-4?

A: p-Hydroxyacetophenone is also used as an intermediate in pharmaceutical and fine-chemical synthesis and can be used in fragrance compositions. The appropriate grade depends on whether the final use is cosmetic, pharmaceutical, or industrial.

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