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    Related: Cosmetic Preservative P-HAP CHA
    • Chlorphenesin CAS 104-29-0
    • Chlorphenesin CAS 104-29-0

    Chlorphenesin CAS 104-29-0

    Chlorphenesin, also called p-chlorophenyl glyceryl ether, CAS 104-29-0, is a white crystalline cosmetic preservative supplied in cosmetic or personal-care preservative grade. Confirm the required grade and specification, then request a quotation with COA/TDS/SDS for bulk supply.

    • CAS: 104-29-0
    • Synonyms: 3-(4-Chlorophenoxy)-1,2-propanediol, p-Chlorophenyl glyceryl ether, Chlorphenesin alcohol, Glycerol alpha-p-chlorophenyl ether, CPC
    • Einecs: 203-192-6
    • Molecular Formula: C₉H₁₁ClO₃
    • Grade: Cosmetic / Personal Care Preservative Grade
    • Package: 25kg/bag (Plastic woven bag with PE liner) or 500kg/1000kg Jumbo Bag.
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    Product Description

    Chlorphenesin CAS 104-29-0 is 3-(4-chlorophenoxy)-1,2-propanediol, also known as p-chlorophenyl glyceryl ether, with molecular formula C9H11ClO3, molecular weight about 202.63 and EINECS 203-192-6.

    Synonyms: 3-(4-Chlorophenoxy)-1,2-propanediol; p-Chlorophenyl glyceryl ether; Chlorphenesin alcohol; Glycerol alpha-p-chlorophenyl ether; CPC.

    CAS: 104-29-0.

    It has the molecular formula C9H11ClO3 and a molecular weight of about 202.63 g/mol.

    It appears as a white to off-white crystalline powder with a faint characteristic odor, odorless at high purity.

    It melts at about 77.0–81.0 °C and has low water solubility of less than 1% at room temperature.

    It is soluble in alcohol, propylene glycol and glycerol, and is stable across a wide pH range with heat stability up to 80 °C.

    It provides useful antibacterial and antifungal activity, especially against molds and yeasts, in water-rich cosmetics.

    It is commonly combined with phenoxyethanol or ethylhexylglycerin for broader preservative coverage.

    It is used in facial creams, lotions, serums, mascara, liquid foundations and wet sheet masks.

    It is also used in deodorants to help control odor-causing bacteria.

    In manufacturing, it is usually pre-dissolved in propylene glycol or butylene glycol, or added to a warmed aqueous phase at 50–60 °C.

    It is approved in the USA, EU, China and Japan with a typical maximum authorized concentration of 0.3%.

    As a raw powder it requires dust control, eye protection and gloves during weighing and mixing.

    Confirm appearance, assay, melting range, related substances, heavy metals, loss on drying and microbial limits as required.

    Store in a cool, dry place away from direct sunlight and strong oxidizing agents, keeping containers tightly sealed.

    Confirm packaging with the requested quantity and destination requirements.

    The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.

    For an RFQ, state the intended use, required grade and specification, quantity, packaging, destination and document needs.

    FAQ - Technical & Supply Chain

    • Q:

      What is Chlorphenesin CAS 104-29-0?

      A: Chlorphenesin CAS 104-29-0 is 3-(4-chlorophenoxy)-1,2-propanediol, with molecular formula C9H11ClO3, molecular weight about 202.63, and EINECS 203-192-6. It is also known as p-chlorophenyl glyceryl ether and is commonly used as a cosmetic preservative.
    • Q:

      How does Chlorphenesin differ from Chlorphenesin Carbamate?

      A: Chlorphenesin is the alcohol form and is used mainly as a cosmetic preservative/biocide. Chlorphenesin carbamate is a different compound with a carbamate group and is associated with pharmaceutical muscle-relaxant use, so the two should not be confused.
    • Q:

      Why is Chlorphenesin often combined with Phenoxyethanol?

      A: Chlorphenesin provides useful antibacterial and antifungal activity, especially against molds and yeasts, while phenoxyethanol contributes broader preservative coverage. The combination is widely used in water-rich cosmetics such as sheet masks, creams, and lotions.
    • Q:

      How should Chlorphenesin be incorporated into a formulation?

      A: It has low cold-water solubility and is more soluble in alcohol, propylene glycol, and glycerol. In manufacturing, it is usually pre-dissolved in a compatible solvent or added to a warmed aqueous phase, then incorporated before final pH and viscosity adjustment.
    • Q:

      What cosmetic products commonly use Chlorphenesin?

      A: It is used in facial creams, lotions, serums, mascara, liquid foundations, and wet sheet masks where water activity is high and protection against fungi or yeast is important. It is typically used as part of a preservative system rather than as the only preservative.

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