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    HomeProductsDaily ChemicalsCosmetic Raw MaterialsPure Allantoin CAS 97-59-6
    • Pure Allantoin CAS 97-59-6

    Pure Allantoin CAS 97-59-6

    Pure Allantoin (CAS 97-59-6) is a highly effective skin-protecting active ingredient utilizing its keratolytic and moisturizing properties to promote cell regeneration and soothe irritated tissue. Chemically identified as 5-Ureidohydantoin or Glyoxyldiureide, this odorless white crystalline powder functions to stimulate healthy tissue growth (granulation) and accelerate the shedding of dead skin cells, making the skin softer and more radiant. As a nature-identical Imidazolidine derivative (historically found in the Comfrey plant), it is extensively integrated into sensitive skin lotions, acne treatments, oral care products (toothpaste for gum health), and pharmaceutical dermatological creams to treat burns and ulcers. We ensure bulk supply capabilities for this material, providing access to competitive factory pricing and customized specifications to meet specific particle size needs (e.g., Micronized for better dispersion) and purity standards (USP/EP/BP Grade). Full technical documentation, including MSDS, TDS, COA, is available to support compliance and safety protocols.

    • CAS: 97-59-6
    • Synonyms: 5-Ureidohydantoin, Glyoxyldiureide, (2,5-Dioxo-4-imidazolidinyl)urea, Cordianine, Allantol
    • Einecs: 202-592-8
    • Molecular Formula: C4H6N4O3
    • Grade: USP (United States Pharmacopeia) / EP (European Pharmacopoeia) / Cosmetic Grade
    • Package: 25kg/Fiber Drum or 25kg/Cardboard Box with PE inner bag
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    Product Description

    Allantoin is a white, odorless, non-toxic crystalline powder widely used as an active ingredient in the cosmetic and pharmaceutical industries. It is produced through a high-purity synthetic process to ensure stability and safety.

    Our Allantoin functions as an excellent skin-soothing agent and keratolytic. It promotes cell proliferation and wound healing, helping to shed the outer layer of the epidermis and promoting healthy tissue formation. It is non-irritating and compatible with a vast range of cosmetic ingredients, making it ideal for sensitive skin formulations, baby products, and high-end repair creams. It is amphoteric and has weak acidity, offering good stability in pH ranges of 4-9.

    1 Physicochemical Properties
    2 Applications
    3 Storage Conditions
    4 Safety Precautions

    Physicochemical Properties

    The following specifications are based on our standard export quality (USP/EP Standards):

    Test ItemSpecification
    AppearanceWhite Crystalline Powder
    Assay (Purity)98.5% – 101.0%
    Melting Point225°C – 236°C (Decomposition)
    Loss on Drying≤ 0.20%
    Residue on Ignition (Ash)≤ 0.10%
    Acidity / AlkalinityPasses Test (Neutral)
    Heavy Metals (Pb)≤ 10 ppm
    Readily Carbonizable SubstancesPasses Test
    SolubilitySlightly soluble in cold water; Soluble in hot water
    pH Value (0.5% Solution)4.5 – 6.0
    Glycoluril≤ 0.1%

    Applications

    Allantoin CAS 97-59-6 is a versatile additive used in various sectors:

    1. Skin Care & Cosmetics:
      • Repair Creams: Used in anti-acne products, scar reduction creams, and sun-repair lotions (typical dosage 0.1% – 0.5%).
      • Moisturizers: Improves the moisture retention capacity of the skin matrix.
      • Sensitive Skin: Reduces irritation in products for baby care and sensitive skin.
    2. Hair Care:
      • Used in shampoos and conditioners to soften keratin, improve scalp health, and reduce dandruff.
    3. Oral Care:
      • Added to toothpaste and mouthwash to protect mucous membranes and assist in healing oral tissues.
    4. Pharmaceuticals:
      • Used in dermatological ointments to treat psoriasis, eczema, and skin ulcers.

    Storage Conditions

    • Environment: Store in a cool, dry, and well-ventilated area.
    • Temperature: Store at room temperature.
    • Packaging: Keep containers tightly sealed. The powder is stable, but exposure to excessive moisture should be avoided to prevent caking.
    • Shelf Life: 24 months from the date of manufacture when stored properly.

    Safety Precautions

    • Toxicity: Allantoin is non-toxic, non-irritating, and non-allergenic. It is considered safe for cosmetic use.
    • Handling: Wear standard dust masks and safety glasses when handling bulk powder to avoid inhaling dust.
    • Skin/Eye Contact:
      • Skin: Wash off with water (though it is beneficial to skin, high concentrations should be rinsed).
      • Eyes: Rinse thoroughly with water.
    • Fire: Not flammable under normal conditions.

    FAQ - Technical & Supply Chain

    • Q:

      How does Pure Allantoin CAS 97-59-6 chemically improve skin texture?

      A: Allantoin (CAS 97-59-6) acts as a mild keratolytic agent; it chemically loosens the intracellular cement holding dead skin cells (corneocytes) together, facilitating desquamation (exfoliation) while simultaneously increasing the water content of the extracellular matrix, resulting in smoother, hydrated skin.
    • Q:

      Is this ingredient suitable for sensitive or compromised skin formulations?

      A: Yes, Allantoin is universally recognized as a non-irritating, soothing protectant (FDA Category I Skin Protectant) and is typically applied in products for diaper rash, sun damage, and sensitive skin to reduce redness and inflammation.
    Documents

    Documents and Product Support

    For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.

    • COA for batch-based quality reference
    • TDS for key physical and chemical information
    • SDS / MSDS for handling, storage, and safety reference
    • Packing information for sample, trial, and bulk orders
    • Technical communication based on application and specification requirements
    Quotation

    Information to Confirm Before Quotation

    Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.

    • Product name and CAS number
    • Application or intended end use
    • Required purity, grade, or specification
    • Sample quantity, trial order, or bulk demand
    • Preferred packing form or net weight
    • Destination country or port
    • Required documents or compliance expectations
    Storage & Handling

    Packaging, Storage, and Handling Notes

    Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.

    Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.

    Supply Support

    Sample, Bulk Order and Repeat Supply Support

    Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.

    For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.

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    Cosmetic Active Ingredient Pharmaceutical Excipient Skin Repair Ingredient Soothing Active Ingredient

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