What is Sodium Butyrate CAS 156-54-7?

Sodium Butyrate CAS 156-54-7 is the sodium salt of butyric acid, with the molecular formula C4H7NaO2, molecular weight about 110.09 g/mol, and EINECS 205-857-6. It is supplied as a white to off-white powder or granules and is also known as sodium butanoate or butyric acid sodium salt.

Why is Sodium Butyrate used in animal nutrition?

Sodium Butyrate is a short-chain fatty acid source that supplies energy to intestinal epithelial cells. In pigs, poultry, and aquaculture it supports gut integrity, helps reduce weaning-related diarrhea, strengthens the gut barrier, and can improve feed intake and growth performance.

What is the difference between raw Sodium Butyrate powder and coated Sodium Butyrate?

Raw Sodium Butyrate has a characteristic butyric acid odor and releases rapidly, while coated or encapsulated grades reduce odor and slow release so more butyrate reaches the lower gut. Coated products are often chosen for feed processing stability, handling, and targeted intestinal delivery.

What are the key specifications of Sodium Butyrate food/pharma grade?

Typical specifications include a white to off-white powder or crystalline appearance, assay of at least 98% on a dry basis, easy solubility in water and ethanol, alkaline solution pH around 7-9, and melting point around 250-253 C.

How does Sodium Butyrate differ from Butyric Acid?

Sodium Butyrate is a solid salt, while butyric acid is a corrosive liquid with stronger volatility and odor. The salt form is easier to handle, dose, and incorporate into feed, food, supplement, and research formulations while providing butyrate activity.

What health or research applications does Sodium Butyrate support?

Beyond animal nutrition, Sodium Butyrate is used as a butyrate source in gut-health and metabolic-support supplements and in research as a histone deacetylase inhibitor. These applications rely on its ability to modulate gene expression and support intestinal barrier function.

Sodium Butyrate CAS 156-54-7

Sodium Butyrate, also called sodium butanoate or butyric acid sodium salt, CAS 156-54-7, is a white to off-white powder or granule supplied in food or pharma grade. Confirm the required grade and specification, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 156-54-7
Synonyms: Sodium butanoate, Butanoic acid sodium salt, Sodium n-butyrate, Butyric acid sodium salt, Na-butyrate
Einecs: 205-857-6
Molecular Formula: C₄H₇NaO₂
Grade: Food/Pharma Grade
Package: 25kg/bag (Plastic woven bag with PE liner) or 500kg/1000kg Jumbo Bag.

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Product Description

Sodium Butyrate CAS 156-54-7 is the sodium salt of butyric acid, also known as sodium butanoate, with molecular formula C4H7NaO2, molecular weight about 110.09 and EINECS 205-857-6.

Synonyms: Sodium butanoate; Butanoic acid sodium salt; Sodium n-butyrate; Butyric acid sodium salt; Na-butyrate.

CAS: 156-54-7.

It has the molecular formula C4H7NaO2 and a molecular weight of about 110.09 g/mol.

It appears as a white to off-white powder or crystalline granules with a characteristic rancid butter odor in raw form.

A typical specification includes assay of at least 98.0% on a dry basis and a melting point of 250–253 °C.

It is easily soluble in water and ethanol, and its solution is alkaline with a pH of about 7.0–9.0.

In animal nutrition, it supplies energy to intestinal epithelial cells and supports gut integrity in pigs, poultry and aquaculture.

Coated or encapsulated grades reduce odor and provide slower release so more butyrate reaches the lower gut.

It is used in human gut-health and metabolic-support supplements, including postbiotic and microbiome-balance formulations.

In research, it is used as a histone deacetylase inhibitor and butyrate source for intestinal barrier studies.

The raw powder has a strong rancid odor, so handling requires dedicated protective clothing and odor control.

It is hygroscopic and can clump and intensify odor if it absorbs moisture.

Store in a cool, dry, well-ventilated area in airtight packaging to prevent odor spread and moisture pickup.

Confirm appearance, assay, loss on drying, pH, heavy metals, microbial limits and residual solvent limits as required.

Use N95 masks or respirators and eye protection during handling, and wash skin contact with soap and water.

Confirm packaging with the requested quantity and destination requirements.

The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.

For an RFQ, state the intended use, required grade and specification, quantity, packaging, destination and document needs.

FAQ - Technical & Supply Chain

Q:
What is Sodium Butyrate CAS 156-54-7?

A: Sodium Butyrate CAS 156-54-7 is the sodium salt of butyric acid, with the molecular formula C4H7NaO2, molecular weight about 110.09 g/mol, and EINECS 205-857-6. It is supplied as a white to off-white powder or granules and is also known as sodium butanoate or butyric acid sodium salt.
Q:
Why is Sodium Butyrate used in animal nutrition?

A: Sodium Butyrate is a short-chain fatty acid source that supplies energy to intestinal epithelial cells. In pigs, poultry, and aquaculture it supports gut integrity, helps reduce weaning-related diarrhea, strengthens the gut barrier, and can improve feed intake and growth performance.
Q:
What is the difference between raw Sodium Butyrate powder and coated Sodium Butyrate?

A: Raw Sodium Butyrate has a characteristic butyric acid odor and releases rapidly, while coated or encapsulated grades reduce odor and slow release so more butyrate reaches the lower gut. Coated products are often chosen for feed processing stability, handling, and targeted intestinal delivery.
Q:
What are the key specifications of Sodium Butyrate food/pharma grade?

A: Typical specifications include a white to off-white powder or crystalline appearance, assay of at least 98% on a dry basis, easy solubility in water and ethanol, alkaline solution pH around 7-9, and melting point around 250-253 C.
Q:
How does Sodium Butyrate differ from Butyric Acid?

A: Sodium Butyrate is a solid salt, while butyric acid is a corrosive liquid with stronger volatility and odor. The salt form is easier to handle, dose, and incorporate into feed, food, supplement, and research formulations while providing butyrate activity.
Q:
What health or research applications does Sodium Butyrate support?

A: Beyond animal nutrition, Sodium Butyrate is used as a butyrate source in gut-health and metabolic-support supplements and in research as a histone deacetylase inhibitor. These applications rely on its ability to modulate gene expression and support intestinal barrier function.

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