N-Acetylneuraminic Acid (sialic acid, NANA, Neu5Ac), CAS 131-48-6, is a high-purity sialic acid supplied for nutraceutical, functional-food, cosmetic and research applications. Confirm the required grade, then request a quotation with COA/TDS/SDS for bulk supply.
N-Acetylneuraminic Acid Powder CAS 131-48-6
- CAS: 131-48-6
- Synonyms: sialic acid, NANA, 5-acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid, lactaminic acid
- Einecs: 205-023-1
- Molecular Formula: C₁₁H₁₉NO₉
- Grade: Pharmaceutical / Nutraceutical grade, ≥98% (HPLC)
- Package: 1 kg aluminum foil bag (with inner PE liner); 25 kg fiber drum (lined with double PE bags); customized packaging available on request
Product Description
N-Acetylneuraminic Acid, CAS 131-48-6, also known as sialic acid, NANA or Neu5Ac, is an acidic monosaccharide and the major representative of sialic acids; the EC/EINECS number is 205-023-1.
Synonyms: sialic acid; NANA; 5-acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid; lactaminic acid.
CAS: 131-48-6.
Molecular formula: C₁₁H₁₉NO₉.
Molecular weight: 309.27.
EC number: 205-023-1.
It is a white to off-white crystalline powder with a melting point of about 184–186 °C (decomposition) and an assay typically ≥98.0% by HPLC on a dry basis.
It is freely soluble in water (about 50 g/L or higher at 20 °C) and practically insoluble in ethanol; the predicted carboxyl pKa is about 2.4.
The optical rotation is about −32° (c=1, water); it is stable under recommended storage but sensitive to moisture and strong oxidizing agents.
It is used as a functional ingredient in nutraceuticals, functional foods and infant-formula research as a source of sialic acid.
It is used in cosmetic formulations and in glycobiology and sialic-acid metabolism research.
It is a high-purity raw material for manufacturers, formulators and researchers, not a finished consumer product.
Confirm assay, appearance, water, related substances, optical rotation, residual solvents, heavy metals and microbial limits; pharmaceutical and nutraceutical grades are available.
Store in tightly closed, moisture-protected containers in a cool, dry environment away from strong oxidizers; use powder-handling controls and suitable PPE.
Confirm the current product-specific specification.
Confirm packaging with the requested quantity and destination requirements.
Document requirements should be confirmed from the current specification, SDS, COA or other product-specific files.
The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.
For an RFQ, state the intended use, required specification, quantity, packaging, destination and document needs.
FAQ - Technical & Supply Chain
-
Q:
What is N-Acetylneuraminic Acid Powder CAS 131-48-6?
A: N-Acetylneuraminic Acid is the sialic acid also known as NANA or Neu5Ac. It has the molecular formula C₁₁H₁₉NO₉ and a molecular weight of about 309.27 g/mol. -
Q:
What are the main applications of N-Acetylneuraminic Acid?
A: It is used in nutraceuticals, functional foods, infant-formula research and cosmetic formulations. It also serves as a research ingredient in glycobiology and sialic-acid metabolism studies. -
Q:
Is this N-Acetylneuraminic Acid powder a finished consumer product?
A: No. It is a high-purity raw material for manufacturers, formulators and researchers. Finished-product dosage, labeling and regulatory compliance should be established for the final formulation. -
Q:
What typical purity and solubility should be expected?
A: Commercial high-purity material is often specified at 98% or higher by HPLC and appears as a white to off-white crystalline powder. N-Acetylneuraminic Acid is freely soluble in water, with water solubility around 50 g/L at 20 °C. -
Q:
How should N-Acetylneuraminic Acid Powder be stored and handled?
A: Keep it in tightly closed, moisture-protected containers in a cool, dry environment and avoid strong oxidizing agents. Use suitable powder-handling controls and PPE during weighing and transfer.
Ordering & Documentation
Key information for document requests, quotations, and supply planning.
Documents
Tell us which documents your procurement team needs. Before an order, we will check whether the quoted source can provide them for the offered lot.
Quotation
Send the CAS number, grade, quantity, packing preference and destination.
Sample & Supply
Ask whether samples, trial quantities or repeat orders are possible. We will check each request against the sourced product and current offer.
Storage & Shipping
Product-specific conditions are confirmed before order.


