What is Sodium Hyaluronate CAS 9067-32-7, and how is it different from hyaluronic acid?

Sodium Hyaluronate is the sodium salt of hyaluronic acid and is supplied as a water-soluble white to off-white powder. Compared with the acid form, it is more soluble and more stable in aqueous formulations, which is why it is the common cosmetic and pharmaceutical form.

What molecular weight grades are available, and how do they affect performance?

High molecular weight grades, usually about 1,000 kDa or above, provide surface film formation and strong moisture retention. Medium grades around 200-1,000 kDa balance hydration and protection, while low grades around 5-200 kDa are often selected for deeper penetration and plumping or anti-aging claims.

Is Sodium Hyaluronate suitable for both cosmetic and pharmaceutical use?

Yes, but the appropriate grade must be selected. Cosmetic and pharmaceutical grades are available; pharmaceutical uses include ophthalmic preparations, topical wound care, and injectable or viscoelastic products where permitted. Purity, microbial limits, and local regulatory requirements should be confirmed for the intended application.

How is Sodium Hyaluronate produced?

It is typically produced by microbial fermentation, commonly using selected bacterial strains, followed by purification and drying. This provides a non-animal-origin polymer with controlled molecular weight, purity, and batch-to-batch consistency for cosmetic and pharmaceutical formulation.

What specifications should be checked before ordering?

Confirm appearance, assay, molecular weight range, pH in a dilute aqueous solution, loss on drying, residue on ignition, heavy metals, and microbial limits. For pharmaceutical applications, also check protein and endotoxin limits when they are relevant, and specify the required grade.

How should Sodium Hyaluronate powder be stored and handled?

Keep it in tightly closed, moisture-protected containers in a cool, dry place away from direct sunlight and strong temperature changes. Use dust-control measures and suitable PPE when weighing or transferring the powder, and reseal opened packaging promptly after each use.

Sodium Hyaluronate CAS 9067-32-7

Sodium Hyaluronate (hyaluronic acid sodium salt), CAS 9067-32-7, is a high-molecular-weight glycosaminoglycan produced by microbial fermentation and supplied for cosmetics, pharmaceuticals and nutraceuticals. Confirm the molecular-weight grade, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 9067-32-7
Synonyms: Hyaluronic acid sodium salt, Hyaluronan sodium, Sodium hyaluronate polymer, poly(sodium hyaluronate), sodium hyaluronate biopolymer
Einecs: 618-620-0
Molecular Formula: (C₁₄H₂₀NNaO₁₁)ₙ
Grade: Cosmetic / Pharmaceutical grade
Package: 1 kg aluminum foil bag; 5 kg & 10 kg fiber drum with double PE liner, or customized on request

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Product Description

Sodium Hyaluronate, CAS 9067-32-7, also known as hyaluronic acid sodium salt or hyaluronan sodium, is a high-molecular-weight glycosaminoglycan produced by microbial fermentation; the EC/EINECS number is 618-620-0.

Synonyms: hyaluronic acid sodium salt; hyaluronan sodium; sodium hyaluronate polymer; poly(sodium hyaluronate); sodium hyaluronate biopolymer.

CAS: 9067-32-7.

Representative molecular formula: (C₁₄H₂₀NNaO₁₁)ₙ.

Molecular weight (monomer unit): approximately 401.30 g/mol; commercial grades are available across low, medium and high molecular-weight ranges.

EC number: 618-620-0.

It is a white to off-white, free-flowing or fibrous powder, practically odorless, freely soluble in water and practically insoluble in organic solvents.

The assay (on dry basis) is typically ≥98.0%; a 0.1–1.0% aqueous solution at 25 °C has a pH of 6.0–7.5.

Loss on drying is ≤10.0%, residue on ignition ≤20.0% and heavy metals ≤20 ppm; viscosity is grade-dependent and specified on the COA.

It is used in cosmetics and personal care, including serums, essences, lotions, creams, masks and hair care, as a humectant and skin-conditioning polymer.

It is used in pharmaceutical and medical applications such as ophthalmic preparations, topical wound care and, where permitted, viscoelastic or injectable products.

It is used in nutraceuticals and functional foods for joint health, skin beauty and anti-aging supplements, alone or with collagen and chondroitin.

It is produced by microbial fermentation (non-animal) using selected bacterial strains, then purified and dried to controlled purity and molecular weight.

Confirm molecular-weight grade, assay, pH, loss on drying, residue on ignition, heavy metals and microbial limits; select cosmetic or pharmaceutical grade and specify the application.

Store in tightly closed, moisture-protected original packaging in a cool, dry place away from direct sunlight and strong temperature changes; reseal promptly after use.

Confirm packaging with the requested quantity and destination requirements.

Document requirements should be confirmed from the current specification, SDS, COA or other product-specific files.

The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.

For an RFQ, state the intended use, required specification, molecular-weight grade, quantity, packaging, destination and document needs.

FAQ - Technical & Supply Chain

Q:
What is Sodium Hyaluronate CAS 9067-32-7, and how is it different from hyaluronic acid?

A: Sodium Hyaluronate is the sodium salt of hyaluronic acid and is supplied as a water-soluble white to off-white powder. Compared with the acid form, it is more soluble and more stable in aqueous formulations, which is why it is the common cosmetic and pharmaceutical form.
Q:
What molecular weight grades are available, and how do they affect performance?

A: High molecular weight grades, usually about 1,000 kDa or above, provide surface film formation and strong moisture retention. Medium grades around 200-1,000 kDa balance hydration and protection, while low grades around 5-200 kDa are often selected for deeper penetration and plumping or anti-aging claims.
Q:
Is Sodium Hyaluronate suitable for both cosmetic and pharmaceutical use?

A: Yes, but the appropriate grade must be selected. Cosmetic and pharmaceutical grades are available; pharmaceutical uses include ophthalmic preparations, topical wound care, and injectable or viscoelastic products where permitted. Purity, microbial limits, and local regulatory requirements should be confirmed for the intended application.
Q:
How is Sodium Hyaluronate produced?

A: It is typically produced by microbial fermentation, commonly using selected bacterial strains, followed by purification and drying. This provides a non-animal-origin polymer with controlled molecular weight, purity, and batch-to-batch consistency for cosmetic and pharmaceutical formulation.
Q:
What specifications should be checked before ordering?

A: Confirm appearance, assay, molecular weight range, pH in a dilute aqueous solution, loss on drying, residue on ignition, heavy metals, and microbial limits. For pharmaceutical applications, also check protein and endotoxin limits when they are relevant, and specify the required grade.
Q:
How should Sodium Hyaluronate powder be stored and handled?

A: Keep it in tightly closed, moisture-protected containers in a cool, dry place away from direct sunlight and strong temperature changes. Use dust-control measures and suitable PPE when weighing or transferring the powder, and reseal opened packaging promptly after each use.

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