Pregabalin (CAS 148553-50-8) is a gabapentinoid compound and gamma-aminobutyric acid (GABA) analog primarily utilized as an Active Pharmaceutical Ingredient (API) in the manufacturing of finished dosage forms for the treatment of neuropathic pain and epilepsy. This (S)-3-(Aminomethyl)-5-methylhexanoic acid functions as a potent calcium channel modulator in Pregabalin API based formulations, binding specifically to the alpha-2-delta subunit to inhibit neurotransmitter release in oral capsules and extended-release tablets. To support industrial-scale requirements, we provide bulk supply with competitive factory pricing and ensure rigorous quality control through customized specifications alongside standard technical documentation, including MSDS, TDS, COA.
Pregabalin CAS 148553-50-8
- CAS: 148553-50-8
- Synonyms: 3-(Aminomethyl)-5-methylhexanoic acid, PGB, beta-Isobutyl-gamma-aminobutyric acid
- Einecs: 604-639-1
- Molecular Formula: C8H17NO2
- Grade: Industrial grade 99%
- Package: 200kg iron drum or 50kg plastic drum packing
Product Description
Product name: Pregabalin,lyric powder
CAS: 148553-50-8
MF: C8H17NO2
MW: 159.23
EINECS: 604-639-1
Melting point: 194-196°C
alpha D23 +10.52° (c = 1.06 in water)
Boiling point: 274.0±23.0 °C(Predicted)
Density： 0.997±0.06 g/cm3(Predicted)
Flash point: 9℃
storage temp： 2-8°C
solubility： deionized water: ≥10mg/mL
pka 4.23±0.10(Predicted)
form white powder
FAQ - Technical & Supply Chain
-
Q:
Is this Pregabalin (CAS 148553-50-8) supplied as a finished drug or raw material?
A: This product is the Active Pharmaceutical Ingredient (API) powder (C8H17NO2) intended strictly for industrial pharmaceutical compounding and manufacturing, not for direct patient consumption. -
Q:
What is the primary mechanism of this molecule in formulation efficacy?
A: It acts by binding to the alpha-2-delta site of voltage-gated calcium channels in central nervous system tissues, which modulates calcium influx and reduces the release of excitatory neurotransmitters.
Documents and Product Support
For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.
- COA for batch-based quality reference
- TDS for key physical and chemical information
- SDS / MSDS for handling, storage, and safety reference
- Packing information for sample, trial, and bulk orders
- Technical communication based on application and specification requirements
Information to Confirm Before Quotation
Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.
- Product name and CAS number
- Application or intended end use
- Required purity, grade, or specification
- Sample quantity, trial order, or bulk demand
- Preferred packing form or net weight
- Destination country or port
- Required documents or compliance expectations
Packaging, Storage, and Handling Notes
Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.
Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.
Sample, Bulk Order and Repeat Supply Support
Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.
For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.
