Can DL-Homocysteine Thiolactone Hydrochloride replace an enantiopure grade?

Not automatically. DL material is racemic, while D or L grades have defined stereochemistry. State the required form and verify downstream stereochemical requirements before substitution.

Which DL-Homocysteine Thiolactone Hydrochloride specifications matter?

Specify identity, assay, stereochemical form, water, related substances, residual solvents and physical form. Commercial research grades may use different assay limits and storage instructions.

Is this material a finished pharmaceutical product?

No. It is supplied for controlled synthesis or research. Pharmaceutical, clinical, food or human-use suitability requires a separately qualified grade, quality-system review and destination-market approval.

How should this DL thiolactone be qualified in a ring-opening or derivatization step?

Use the actual lot at the planned stoichiometry and compare dissolution, conversion, reaction time, related substances and final-product impurities. A matching assay alone cannot show whether water or route impurities will behave equivalently in the process.

DL-Homocysteine Thiolactone Hydrochloride CAS 6038-19-3

DL-Homocysteine Thiolactone Hydrochloride is correctly identified by CAS 6038-19-3 and EC 227-923-3 . Its molecular formula is C4H8ClNOS and molecular weight is 153.63 g/mol. CAS 6027-13-0 identifies DL-homocysteine and should not be used for this thiolactone hydrochloride. The product is offered for controlled synthesis, derivatization and research projects, with stereochemical form, assay, impurities, water and handling requirements defined by the exact specification and COA.

CAS: 6038-19-3
Synonyms: DL-Homocysteine Thiolactone Hydrochloride, DL-Homocysteine Thiolactone HCl, 3-Aminothiolan-2-one hydrochloride, Homocysteine thiolactone hydrochloride
Einecs: 227-923-3
Molecular Formula: C₄H₈ClNOS
Grade: Confirm identity by an appropriate analytical method, assay basis, related substances, residual solvents and storage requirements against the current COA; buyer qualification is required.
Package: State required quantity and destination; confirm the current container, light or moisture protection, net weight, storage conditions and transport requirements against the current COA and SDS.

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Product Description

1 Identity and physicochemical profile

2 Applications and grade selection

3 Storage and handling

4 Safety, documentation and procurement

Identity and physicochemical profile

Item	Technical guidance
Correct identity	DL-Homocysteine thiolactone hydrochloride; 3-aminothiolan-2-one hydrochloride
CAS / EC	6038-19-3 / 227-923-3
Formula / molecular weight	C₄H₈ClNOS / 153.63 g/mol
Stereochemical form	DL or racemic material; do not substitute an enantiopure D or L grade without route assessment
Identity boundary	CAS 6027-13-0 refers to DL-homocysteine, not the thiolactone hydrochloride
Key purchase controls	Identity, assay, stereochemical form, water, related substances, physical form and lot traceability

Applications and grade selection

DL-Homocysteine Thiolactone Hydrochloride is evaluated as a cyclic thioester amino-compound intermediate in ring-opening, derivatization and sulfur-containing synthesis routes, as well as controlled biochemical research. It should not be presented as a finished pharmaceutical or as automatically suitable for human, food or clinical use.

Confirm that the project requires the DL material and not an enantiopure homocysteine thiolactone salt.
Compare identity, assay, water, related substances and reaction performance using the buyer’s approved methods.
Define any research, GMP, compendial, traceability or change-control requirements before quotation.

Storage and handling

Store tightly closed and protected from moisture and incompatible materials under the conditions stated in the current SDS and product documentation. Use supplier-specific temperature instructions rather than a generic room-temperature, refrigerated or frozen claim.

Safety, documentation and procurement

Use gloves, eye protection, dust control and appropriate ventilation according to the current SDS and site risk assessment. Procurement should state the stereochemical form, specification, use, quantity, packaging, destination and required quality documents.

FAQ - Technical & Supply Chain

Q:
Can DL-Homocysteine Thiolactone Hydrochloride replace an enantiopure grade?

A: Not automatically. DL material is racemic, while D or L grades have defined stereochemistry. State the required form and verify downstream stereochemical requirements before substitution.
Q:
Which DL-Homocysteine Thiolactone Hydrochloride specifications matter?

A: Specify identity, assay, stereochemical form, water, related substances, residual solvents and physical form. Commercial research grades may use different assay limits and storage instructions.
Q:
Is this material a finished pharmaceutical product?

A: No. It is supplied for controlled synthesis or research. Pharmaceutical, clinical, food or human-use suitability requires a separately qualified grade, quality-system review and destination-market approval.
Q:
How should this DL thiolactone be qualified in a ring-opening or derivatization step?

A: Use the actual lot at the planned stoichiometry and compare dissolution, conversion, reaction time, related substances and final-product impurities. A matching assay alone cannot show whether water or route impurities will behave equivalently in the process.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

COA, TDS, SDS/MSDS and packing details are available on request.

Quotation

Send the CAS number, grade, quantity, packing preference and destination.

Sample & Supply

Support is available for samples, trial orders, bulk and repeat supply.

Storage & Shipping

Product-specific conditions are confirmed before order.

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