Cysteamine Hydrochloride (Cysteamine HCl) CAS 156-57-0

Product Overview

Cysteamine Hydrochloride is supplied as an aminothiol intermediate used in thiol-mediated reactions, reduction systems, and specialty synthesis processes. It is suitable for pharmaceutical intermediate manufacturing, laboratory synthesis, and selected industrial processing applications where reactive sulfur functionality and good water solubility are required.

This material is commonly handled as a hygroscopic solid and is typically selected where controlled reactivity, salt form stability, and compatibility with aqueous systems are important for process design and formulation handling.

Product Information / Specifications

Physical & Chemical Properties

Quality Control for Cysteamine Hydrochloride

For purchasing specifications, distinguish cysteamine hydrochloride assay from chromatographic area purity and state whether the result is on an as-received or dry basis. Agree limits for water, color and cystamine, the disulfide oxidation product. A titration result alone does not establish the complete impurity profile.

Validated HPLC methods can separate cysteamine from cystamine. Select sample preparation and detection suitable for the supplied grade and matrix; a method validated for a finished formulation is not automatically validated for the raw material. We can provide chromatographic data for the selected grade, with the test method and reporting basis.

Applications

• Pharmaceutical and fine-chemical synthesis: an aminothiol building block for routes requiring both amino and thiol functionality.
• Reduction and nucleophilic reactions: selection depends on reaction pH, salt form and the required thiol content.
• Process development and scale-up: control water and oxidation-related impurities when comparing grades or transferring a synthesis route.

Selecting Related Sulfur Intermediates

For comparing thiol functionality, thioglycolic acid and 3-mercaptopropionic acid contain a carboxyl group instead of the amino group of cysteamine. Their acid-base behavior and reaction roles differ; neither is a direct replacement for cysteamine hydrochloride.

Other sulfur building blocks include benzyl mercaptan, a thiol with a benzyl group, and DL-homocysteine thiolactone hydrochloride, which contains a cyclic thioester rather than a free thiol. Select these materials by the target structure and synthesis route, not as equivalent grades of cysteamine hydrochloride.

Packaging

Packaging may vary by grade and supply arrangement. The material is commonly packed in sealed containers suitable for moisture-sensitive chemical products.

Storage Conditions

Store in a cool, dry, and well-ventilated place in tightly closed containers. Protect from moisture, direct light, and air exposure.

Follow the storage temperature and atmosphere stated in the supplied product documentation; refrigeration requirements depend on the grade.

Safety Precautions

• Avoid contact with skin, eyes, and clothing during handling.
• Use appropriate protective equipment and suitable workplace ventilation.
• Avoid dust formation and keep away from strong oxidizing agents.
• Handle and store Cysteamine Hydrochloride in accordance with its SDS and site safety procedures.
• Dispose of residues and packaging in accordance with local regulatory requirements.