Piperazine, also referred to as anhydrous piperazine, 1,4-diazacyclohexane, or hexahydropyrazine, is a cyclic diamine corresponding to CAS 110-85-0 and widely used as an intermediate in epoxy resin curing systems and pharmaceutical synthesis. Its reactivity is based on two secondary amine groups within a heterocyclic structure, enabling controlled crosslinking reactions in resin formulations and serving as a building block in active ingredient manufacturing. The material is supplied with competitive factory pricing, customized specifications, complete documentation including MSDS, TDS, COA, and reliable bulk supply.
Piperazine Anhydrous (CAS 110-85-0)
- CAS: 110-85-0
- Synonyms: Piperazine, Anhydrous piperazine, 1,4-Diazacyclohexane, Hexahydropyrazine
- Einecs: 203-808-3
- Molecular Formula: C₄H₁₀N₂
- Grade: 99.5%
- Package: 25kg/drum or as required
Product Description
Product Overview
Piperazine Anhydrous is provided for industrial use as a cyclic amine intermediate in chemical manufacturing routes that require reactive diamine functionality. It is commonly selected for synthesis systems in pharmaceutical processing, polymer-related chemistry, and auxiliary chemical production.
This product is more appropriately positioned as an industrial chemical intermediate rather than a finished end-use formulation ingredient. Product selection is generally based on identity consistency, purity level, moisture control, and compatibility with the intended synthesis or processing route.
Product Information / Specifications
| Product Name | Piperazine Anhydrous |
| Synonyms | Diethylenediamine; 1,4-Diazacyclohexane |
| CAS Number | 110-85-0 |
| EINECS Number | 203-808-3 |
| Molecular Formula | C4H10N2 |
| Molecular Weight | 86.14 g/mol |
| Typical Grade | 99.5% |
| Standard Packaging | 25 kg/drum or as required |
| Product Identity | Industrial chemical / cyclic diamine intermediate |
Physical & Chemical Properties
| Appearance | Colorless or white crystalline powder or needle-like crystals |
| Density | 0.874 g/cm³ |
| Melting Point | 107–111°C |
| Boiling Point | 146–148°C |
| Flash Point | 49.7–65°C (closed cup) |
| Solubility | 150 g/L in water at 20°C; soluble in ethanol; insoluble in ether |
| pH | 10.8–11.8 (10% aqueous solution) |
| Vapor Pressure | 4.049 mmHg at 25°C |
| Stability Note | Stable under normal conditions, hygroscopic, light sensitive, and incompatible with strong oxidizing agents, strong acids, acid anhydrides, and acid chlorides |
Applications
- Pharmaceutical intermediates for synthesis routes including anthelmintic and antibacterial-related production
- Polymer additives and related material modification systems
- Rubber-related chemical applications
- Preservative, antioxidant, and gas purification related industrial uses
- Specialty chemical synthesis where cyclic diamine functionality is required
Packaging
Standard packaging is commonly supplied in 25 kg drums or according to shipment requirement.
Packaging information may vary by grade, destination, and transport arrangement.
Storage Conditions
- Store in a dry, ventilated, and cool warehouse away from direct sunlight.
- Recommended storage temperature is below 30°C.
- Store separately from oxidants, acids, and incompatible chemicals.
- Avoid contact with humid air and prolonged light exposure during storage.
Safety Precautions
- Handle with protective gloves, goggles, and suitable respiratory protection where required.
- Avoid skin and eye contact and reduce exposure to dust or vapors during handling.
- Use suitable ventilation and sealed handling procedures where possible.
- Keep away from strong acids, oxidizing agents, and other incompatible reactive substances.
- Refer to the latest SDS before storage, transport, and industrial use.
FAQ
FAQ - Technical & Supply Chain
Documents and Product Support
For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.
- COA for batch-based quality reference
- TDS for key physical and chemical information
- SDS / MSDS for handling, storage, and safety reference
- Packing information for sample, trial, and bulk orders
- Technical communication based on application and specification requirements
Information to Confirm Before Quotation
Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.
- Product name and CAS number
- Application or intended end use
- Required purity, grade, or specification
- Sample quantity, trial order, or bulk demand
- Preferred packing form or net weight
- Destination country or port
- Required documents or compliance expectations
Packaging, Storage, and Handling Notes
Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.
Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.
Sample, Bulk Order and Repeat Supply Support
Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.
For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.







