• L-Hydroxyproline CAS 51-35-4

L-Hydroxyproline CAS 51-35-4

L-Hydroxyproline is supplied as an amino acid derivative used mainly in pharmaceutical, biochemical and synthesis-oriented applications. This material is typically handled as an intermediate or specialty raw material rather than a consumer-facing ingredient. It is commonly provided as a white crystalline powder with grade-dependent documentation for technical evaluation and sourcing.

 

  • CAS: 51-35-4
  • Synonyms: trans-4-Hydroxy-L-proline; (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid; Hyp
  • Einecs: 200-091-9
  • Molecular Formula: C5H9NO3
  • Grade: Industrial / Technical / Biochemical grade, according to supplied specification
  • Package: Standard export packaging, according to supplied grade and order quantity
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Product Description

Product Information / Specifications

Product NameL-Hydroxyproline
CAS Number51-35-4
Synonymstrans-4-Hydroxy-L-proline; (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid; Hyp
EC Number200-091-9
Molecular FormulaC5H9NO3
Molecular Weight131.13
Product IdentityAmino acid derivative / specialty chemical / intermediate-use raw material
Supply FormSolid powder or crystalline material, depending on supplied grade

Physical & Chemical Properties

AppearanceWhite to almost white crystalline powder or crystals
Physical StateSolid
Water SolubilitySoluble in water; actual solubility may be reported according to grade or test condition
Melting PointTypically reported around 273–274°C
Recommended Handling PositionTechnical-grade evaluation should follow the supplied specification and batch documentation

Applications

  • Pharmaceutical intermediate use where hydroxyproline functionality is required in synthesis routes.
  • Biochemical and laboratory use as an amino acid derivative for controlled technical work.
  • Specialty synthesis applications involving chiral or structure-specific raw material selection.
  • Research and process development programs that require defined hydroxyproline identity and batch documentation.

Packaging

Packaging format may vary according to grade, batch size, and supply arrangement. This product is generally supplied in sealed inner packaging with suitable outer protection for routine storage and transport. Packaging details may be confirmed according to the ordered grade and quantity.

Storage Conditions

Store in a cool, dry, and well-closed container away from moisture, direct heat, and prolonged air exposure. Storage recommendations may differ by grade and manufacturer specification, so batch-level technical documents should be followed where applicable.

Safety Precautions

Handle with appropriate industrial hygiene practice and use suitable personal protective equipment during weighing, transfer, and processing. Avoid unnecessary dust generation and direct contact with eyes, skin, or clothing. Refer to the latest SDS for product-specific handling, storage, and disposal guidance before use.

FAQ

1. What is L-Hydroxyproline used for?

L-Hydroxyproline is mainly supplied for pharmaceutical, biochemical, and synthesis-oriented applications where a defined hydroxyproline raw material is required.

2. Is L-Hydroxyproline the same as trans-4-Hydroxy-L-proline?

In standard commercial and catalog usage, L-Hydroxyproline is commonly listed as trans-4-Hydroxy-L-proline for CAS 51-35-4. Identity should always be confirmed against the batch specification.

3. Is this product positioned as a consumer ingredient?

No. This material is generally handled as an intermediate-use or specialty raw material for technical, research, or manufacturing-related applications.

4. What technical documents may be available with supply?

Depending on grade and batch, technical documents such as COA, TDS, and SDS may be provided for evaluation and routine supply support.

5. What should buyers check before selecting a grade?

Buyers typically confirm identity, purity standard, intended use, packaging format, and storage requirements against the supplied specification before use in process or development work.

6. Is water solubility relevant for this product?

Yes. L-Hydroxyproline is generally handled as a water-soluble amino acid derivative, but the reported value and testing condition may vary by specification.

7. How should L-Hydroxyproline be stored?

It should be kept tightly closed in a cool and dry place, protected from moisture and unnecessary exposure to air, and stored according to the current batch documentation.

FAQ - Technical & Supply Chain

Documents

Documents and Product Support

For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.

  • COA for batch-based quality reference
  • TDS for key physical and chemical information
  • SDS / MSDS for handling, storage, and safety reference
  • Packing information for sample, trial, and bulk orders
  • Technical communication based on application and specification requirements
Quotation

Information to Confirm Before Quotation

Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.

  • Product name and CAS number
  • Application or intended end use
  • Required purity, grade, or specification
  • Sample quantity, trial order, or bulk demand
  • Preferred packing form or net weight
  • Destination country or port
  • Required documents or compliance expectations
Storage & Handling

Packaging, Storage, and Handling Notes

Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.

Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.

Supply Support

Sample, Bulk Order and Repeat Supply Support

Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.

For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.

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