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    HomeProductsLife SciencePharmaceutical‌Propylene Glycol Block Polyether F68 CAS 9003‑11‑6
    • ‌Propylene Glycol Block Polyether F68 CAS 9003‑11‑6
    • ‌Propylene Glycol Block Polyether F68 CAS 9003‑11‑6

    ‌Propylene Glycol Block Polyether F68 CAS 9003‑11‑6

    Propylene Glycol Block Polyether F68 CAS 9003-11-6, also known as Poloxamer 188, Pluronic F68, or Polyether F68, is a nonionic EO/PO block copolymer supplied as a surfactant, emulsifier, dispersant, and solubilizer for pharmaceutical, cosmetic, bioprocessing, and industrial formulation systems. It is supplied in 99% grade with 200 kg iron drum and 50 kg plastic drum packaging options. COA, TDS, and SDS can be provided according to grade and order requirements.

    • CAS: 9003-11-6
    • Synonyms: Polyether F68, Poloxamer 188, Pluronic F68, EO PO Block Copolymer
    • Einecs: 500-039-7
    • Molecular Formula: EO/PO block copolymer (variable average)
    • Grade: 99%
    • Package: 200kg iron drum, 50kg plastic drum packaging.
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    Product Description

    Product Overview

    Poloxamer 188 is supplied as a nonionic triblock polyether composed of polyethylene oxide and polypropylene oxide segments. It is commonly used as a formulation ingredient and processing aid where surface activity, water solubility, dispersion support, and system stability are required.

    This material is suitable for pharmaceutical excipient applications as well as selected industrial surfactant systems. Technical documents such as COA, TDS, and SDS may be provided according to the supplied grade.

    Product Information / Specifications
    Product Name Poloxamer 188
    Synonyms Polyether F68; Pluronic F68; EO-PO Block Copolymer
    CAS Number 9003-11-6
    Product Identity Nonionic EO-PO block copolymer
    Primary Functions Solubilization, emulsification, dispersion, wetting, and formulation stabilization
    Application Type Pharmaceutical excipient and industrial formulation ingredient
    Documentation COA, TDS, and SDS may be provided according to the supplied grade
    Physical & Chemical Properties
    Appearance White to off-white solid, depending on grade and physical form
    Solubility Readily soluble in water
    pH (1% Aqueous Solution) Typically within a near-neutral range
    Average Molecular Weight Approximately 8350–8400
    Performance Characteristics Suitable for low-foam, solubilizing, dispersing, and stabilizing functions in compatible systems
    Applications
    • Used in pharmaceutical formulations as a nonionic excipient for solubilization, dispersion, and formulation stabilization.
    • Suitable for water-based systems requiring emulsification support and processing compatibility.
    • Applied in cosmetic and personal care formulation systems where nonionic surfactant functionality is required.
    • Used in selected industrial formulations as a low-foam surfactant, dispersing aid, or process additive.
    • Suitable for formulation development where EO-PO block copolymer structure is required for system balance and compatibility.
    Packaging

    Standard packaging may be supplied in 200 kg drums, 50 kg plastic drums, or other industrial packaging formats according to grade and shipment arrangement.

    Packaging type and net weight may vary depending on physical form, export requirements, and order specification.

    Storage Conditions
    • Store in a cool, dry, and well-ventilated indoor area.
    • Keep containers tightly closed when not in use.
    • Protect from direct heat, moisture, and strong light exposure.
    • Handle and transport according to general chemical storage requirements.
    Safety Precautions
    • Use appropriate personal protective equipment during handling.
    • Avoid direct contact with eyes and prolonged skin exposure.
    • Operate in accordance with plant safety procedures and applicable ventilation requirements.
    • Refer to the current SDS before storage, transport, handling, or formulation use.

    FAQ - Technical & Supply Chain

    • Q:

      What is Propylene Glycol Block Polyether F68 CAS 9003-11-6 used for?

      A: Propylene Glycol Block Polyether F68 is used as a nonionic EO/PO block copolymer surfactant, emulsifier, dispersant, and solubilizer in pharmaceutical, cosmetic, bioprocessing, and industrial formulation systems.
    • Q:

      Is Polyether F68 the same as Poloxamer 188 or Pluronic F68?

      A: Yes. Polyether F68, Poloxamer 188, and Pluronic F68 are commonly used names for the same EO/PO block copolymer material identified by CAS 9003-11-6.
    • Q:

      What should buyers confirm before ordering Polyether F68?

      A: Buyers should confirm average molecular weight range, EO/PO composition, hydroxyl value, moisture, appearance, pH, heavy metals or microbiological requirements where applicable, and packaging requirements.
    • Q:

      What is the average molecular weight range of Polyether F68?

      A: Polyether F68 (Poloxamer 188) has an average molecular weight of approximately 8350–8400 g/mol. Within the Poloxamer series, F68 has a typical polyethylene oxide (PEO) content around 80% by weight, giving it relatively high water solubility and moderate surface activity across a range of temperatures.
    • Q:

      How does Polyether F68 differ from other Poloxamer grades such as Poloxamer 407?

      A: Poloxamer 188 (F68) has a higher PEO content (~80%) and lower molecular weight (~8350–8400) compared to Poloxamer 407 (F127, ~12600 g/mol, ~70% PEO). F68 forms weaker gels and is preferred for formulations requiring lower viscosity and higher water solubility, while F127 is used when thermoreversible gelation is desired.
    • Q:

      What storage conditions are recommended for Polyether F68?

      A: Polyether F68 should be stored in a cool, dry, well-ventilated area away from direct sunlight and moisture. The material is hygroscopic and should be kept in sealed containers. Recommended storage temperature is below 40°C to avoid thermal degradation of the EO/PO block structure. Under proper conditions, the product has a typical shelf life of 24 months.
    Documents

    Documents and Product Support

    For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.

    • COA for batch-based quality reference
    • TDS for key physical and chemical information
    • SDS / MSDS for handling, storage, and safety reference
    • Packing information for sample, trial, and bulk orders
    • Technical communication based on application and specification requirements
    Quotation

    Information to Confirm Before Quotation

    Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.

    • Product name and CAS number
    • Application or intended end use
    • Required purity, grade, or specification
    • Sample quantity, trial order, or bulk demand
    • Preferred packing form or net weight
    • Destination country or port
    • Required documents or compliance expectations
    Storage & Handling

    Packaging, Storage, and Handling Notes

    Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.

    Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.

    Supply Support

    Sample, Bulk Order and Repeat Supply Support

    Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.

    For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.

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    Product Categories

    Tags:

    Block Copolymer Surfactant Dispersing Agent Polyether Emulsifier

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