Propylene Glycol Block Polyether F68, commonly known as Poloxamer 188, is a nonionic EO/PO block copolymer used as an industrial and pharmaceutical surfactant ingredient. Identified by CAS No. 9003‑11‑6, this triblock polyether consists of a central polypropylene oxide block flanked by polyethylene oxide chains, providing excellent water solubility, low toxicity profile, and surface‑active properties. It is widely applied in nonionic surfactant systems and pharmaceutical formulations where emulsification stability, dispersion control, and processing compatibility are required. The material is supplied with standard documentation including MSDS, TDS, and COA for bulk handling and formulation use.
Propylene Glycol Block Polyether F68 CAS 9003‑11‑6
- CAS: 9003-11-6
- Synonyms: Polyether F68, Poloxamer 188, Pluronic F68, EO PO Block Copolymer
- Einecs: 500‑039‑7
- Molecular Formula: HO(C₂H₄O)ₙ(C₃H₆O)ₘ(C₂H₄O)ₙH。
- Grade: 99%
- Package: 200kg iron drum, 50kg plastic drum packaging.
Product Description
Poloxamer 188 is supplied as a nonionic triblock polyether composed of polyethylene oxide and polypropylene oxide segments. It is commonly used as a formulation ingredient and processing aid where surface activity, water solubility, dispersion support, and system stability are required.
This material is suitable for pharmaceutical excipient applications as well as selected industrial surfactant systems. Technical documents such as COA, TDS, and SDS may be provided according to the supplied grade.
| Product Name | Poloxamer 188 |
| Synonyms | Polyether F68; Pluronic F68; EO-PO Block Copolymer |
| CAS Number | 9003-11-6 |
| Product Identity | Nonionic EO-PO block copolymer |
| Primary Functions | Solubilization, emulsification, dispersion, wetting, and formulation stabilization |
| Application Type | Pharmaceutical excipient and industrial formulation ingredient |
| Documentation | COA, TDS, and SDS may be provided according to the supplied grade |
| Appearance | White to off-white solid, depending on grade and physical form |
| Solubility | Readily soluble in water |
| pH (1% Aqueous Solution) | Typically within a near-neutral range |
| Average Molecular Weight | Approximately 8350–8400 |
| Performance Characteristics | Suitable for low-foam, solubilizing, dispersing, and stabilizing functions in compatible systems |
- Used in pharmaceutical formulations as a nonionic excipient for solubilization, dispersion, and formulation stabilization.
- Suitable for water-based systems requiring emulsification support and processing compatibility.
- Applied in cosmetic and personal care formulation systems where nonionic surfactant functionality is required.
- Used in selected industrial formulations as a low-foam surfactant, dispersing aid, or process additive.
- Suitable for formulation development where EO-PO block copolymer structure is required for system balance and compatibility.
Standard packaging may be supplied in 200 kg drums, 50 kg plastic drums, or other industrial packaging formats according to grade and shipment arrangement.
Packaging type and net weight may vary depending on physical form, export requirements, and order specification.
- Store in a cool, dry, and well-ventilated indoor area.
- Keep containers tightly closed when not in use.
- Protect from direct heat, moisture, and strong light exposure.
- Handle and transport according to general chemical storage requirements.
- Use appropriate personal protective equipment during handling.
- Avoid direct contact with eyes and prolonged skin exposure.
- Operate in accordance with plant safety procedures and applicable ventilation requirements.
- Refer to the current SDS before storage, transport, handling, or formulation use.
FAQ - Technical & Supply Chain
Documents and Product Support
For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.
- COA for batch-based quality reference
- TDS for key physical and chemical information
- SDS / MSDS for handling, storage, and safety reference
- Packing information for sample, trial, and bulk orders
- Technical communication based on application and specification requirements
Information to Confirm Before Quotation
Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.
- Product name and CAS number
- Application or intended end use
- Required purity, grade, or specification
- Sample quantity, trial order, or bulk demand
- Preferred packing form or net weight
- Destination country or port
- Required documents or compliance expectations
Packaging, Storage, and Handling Notes
Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.
Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.
Sample, Bulk Order and Repeat Supply Support
Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.
For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.





