• Sodium tert-Butoxide CAS 865-48-5

Sodium tert-Butoxide CAS 865-48-5

Sodium tert-Butoxide is positioned in industrial supply as a highly reactive alkoxide base, commonly used in organic synthesis, condensation reactions, and deprotonation processes. It is valued for its strong basicity and relatively low nucleophilicity, making it suitable for elimination reactions and selective transformations in fine chemical and pharmaceutical intermediate production.

In commercial supply, it is typically provided either as a moisture-sensitive solid powder or as a solution in compatible solvents such as tert-butanol. Due to its high reactivity toward moisture and air, it is handled under controlled conditions and used as a processing reagent rather than a direct formulation ingredient. Standard packaging is available with appropriate moisture protection, along with COA, TDS, and SDS documentation for industrial use.

  • CAS: 865-48-5
  • Synonyms: Sodium tert-butylate; Sodium t-butoxide; NaOtBu
  • Einecs: 212-740-9
  • Molecular Formula: C₄H₉NaO
  • Grade: Typically supplied for industrial synthesis and reagent use
  • Package: Available in sealed, moisture-protected packaging; packaging format depends on solid or solution supply form and order requirements
Request a quote
Share:

Product Description

Physicochemical Properties

ItemDescription
AppearanceWhite to off-white powder or solid
OdorCharacteristic odor
SolubilitySoluble in alcohols such as tert-butanol; reacts with water
Melting PointApprox. 180–190°C (decomposition)
ReactivityStrong base; reacts vigorously with water and acids
Moisture SensitivityHighly hygroscopic and moisture sensitive
Handling CharacteristicsAir-sensitive; requires dry handling conditions

Typical Applications

  • Organic synthesis: Used as a strong base in elimination, condensation, and deprotonation reactions.
  • Pharmaceutical and fine chemical intermediates: Applied in reaction steps requiring controlled base strength and selectivity.
  • Polymer and specialty chemical processing: Used as a catalyst or initiator in certain polymerization systems.
  • Transesterification and alkoxide reactions: Acts as a reagent in ester exchange and related transformations.

Use conditions should be carefully evaluated due to its strong reactivity and moisture sensitivity.

Packaging

Sodium tert-Butoxide is supplied in tightly sealed, moisture-resistant containers to protect against air and humidity exposure. Common packaging formats include lined drums, sealed metal containers, or specialized containers for air-sensitive chemicals.

For solution grades, it may be supplied in drums or IBC containers compatible with the solvent system. Packaging is designed to maintain product stability during storage and transportation, with bulk supply arrangements available based on order requirements.

Storage

Store in a cool, dry, and well-ventilated area under inert or low-moisture conditions where possible. Keep containers tightly closed and protected from air and humidity.

Avoid contact with water, acids, and oxidizing agents. Maintain strict moisture control during storage and handling.

FAQ

Can bulk supply be arranged?
Yes, packaging and supply formats can be arranged based on order volume and logistics requirements.

What is the primary function of Sodium tert-Butoxide?
It is used as a strong base reagent in organic synthesis and industrial chemical reactions.

Is Sodium tert-Butoxide moisture sensitive?
Yes, it reacts readily with moisture and should be handled under dry conditions.

In what forms is it supplied?
It can be supplied as a solid powder or as a solution in compatible solvents such as tert-butanol.

What safety considerations are important?
Due to its strong reactivity, it should be handled with appropriate protective measures and kept away from water and acids.

Is documentation available for procurement?
COA, TDS, and SDS can be provided for safe handling and quality evaluation.

FAQ - Technical & Supply Chain

Documents

Documents and Product Support

For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.

  • COA for batch-based quality reference
  • TDS for key physical and chemical information
  • SDS / MSDS for handling, storage, and safety reference
  • Packing information for sample, trial, and bulk orders
  • Technical communication based on application and specification requirements
Quotation

Information to Confirm Before Quotation

Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.

  • Product name and CAS number
  • Application or intended end use
  • Required purity, grade, or specification
  • Sample quantity, trial order, or bulk demand
  • Preferred packing form or net weight
  • Destination country or port
  • Required documents or compliance expectations
Storage & Handling

Packaging, Storage, and Handling Notes

Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.

Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.

Supply Support

Sample, Bulk Order and Repeat Supply Support

Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.

For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.

Contact Form

Use our contact form to send us your questions, suggestions or comments. We will respond as soon as possible.