• Phenylethyl Resorcinol CAS 3777-69-3
  • Phenylethyl Resorcinol CAS 3777-69-3

Phenylethyl Resorcinol CAS 3777-69-3

Phenylethyl Resorcinol (CAS 3777-69-3), chemically defined as 4-(1-phenylethyl)benzene-1,3-diol, is a synthetic phenolic compound utilized as a high-performance tyrosinase inhibitor in the production of cosmetic brightening formulations. This crystalline raw material, also technically identified as 4-(1-phenylethyl)resorcinol or 4-(alpha-methylbenzyl)resorcinol, serves as a functional ingredient in the industrial compounding of skin care emulsions, specifically incorporated into the oil phase to ensure stability and efficacy in inhibiting melanin synthesis. We provide bulk supply of this cosmetic grade ingredient with competitive factory pricing to meet commercial manufacturing schedules. Our supply chain adheres to strict purity standards, making MSDS, TDS, COA available alongside customized specifications to support diverse formulation requirements.

  • CAS: 3777-69-3
  • Synonyms: 4-(1-phenylethyl)benzene-1,3-diol, 4-(1-phenylethyl)resorcinol, 4-(alpha-methylbenzyl)resorcinol, 1,3-Benzenediol 4-(1-phenylethyl)-
  • Einecs: 480-070-0
  • Molecular Formula: C14H14O2
  • Grade: Cosmetic Grade / Skin-Whitening Grade
  • Package: 1 kg foil bag / 5 kg aluminum tin / 25 kg drum
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Product Description

Phenylethyl Resorcinol (also known as SymWhite® 377 equivalent) is a high-efficiency skin-lightening and anti-oxidant active widely used in premium whitening formulas. It shows strong inhibitory activity on tyrosinase and offers excellent stability compared with traditional whitening agents.

Our factory supplies high-purity Phenylethyl Resorcinol with stable color, low impurities, and verified performance in emulsion, gel, serum, lotion, and transparent essence systems.

Physicochemical Properties

PropertySpecification
AppearanceWhite to off-white crystalline powder
Purity (HPLC)≥ 99%
Melting Point78 – 82°C
SolubilitySoluble in DMSO, ethanol, propylene glycol; slightly soluble in oils
OdorSlight characteristic odor
StabilityExcellent stability under normal cosmetic processing temperature
Heavy Metals≤ 10 ppm
Loss on Drying≤ 0.5%

Applications

Phenylethyl Resorcinol is mainly used in high-end whitening and brightening formulations. Typical applications include:

  • Whitening & brightening face creams
  • Anti-pigmentation serums
  • Spot-removal essences
  • Sunscreen enhancement formulas
  • Skin-tone evening products
  • Premium dermocosmetic whitening lines

Recommended dosage: 0.1–0.5% depending on formulation requirements.


Storage Conditions

  • Store in a cool, dry place, away from light.
  • Keep container tightly sealed after opening.
  • Recommended storage temperature: 2–10°C.
  • Avoid long-term exposure to humidity to prevent powder discoloration.

Safety Precautions

  • Avoid direct skin or eye contact with raw powder.
  • Use protective gloves and masks during handling.
  • Suitable for professional cosmetic manufacturing only—not for retail use.
  • Follow your region’s cosmetic compliance requirements during formulation.

FAQ - Technical & Supply Chain

  • Q:

    How is Phenylethyl Resorcinol (CAS 3777-69-3) chemically distinguished from standard Resorcinol?

    A: Phenylethyl Resorcinol is a derivative of resorcinol characterized by the attachment of a phenylethyl group at the 4-position, which significantly enhances its lipophilicity and inhibitory activity against tyrosinase compared to unsubstituted resorcinol.
  • Q:

    Is Phenylethyl Resorcinol suitable for aqueous or oil-based formulation processes?

    A: Due to its chemical structure, Phenylethyl Resorcinol is intended for incorporation into the oil phase of cosmetic emulsions or solubilization in non-polar solvents during the industrial compounding process.
Documents

Documents and Product Support

For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.

  • COA for batch-based quality reference
  • TDS for key physical and chemical information
  • SDS / MSDS for handling, storage, and safety reference
  • Packing information for sample, trial, and bulk orders
  • Technical communication based on application and specification requirements
Quotation

Information to Confirm Before Quotation

Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.

  • Product name and CAS number
  • Application or intended end use
  • Required purity, grade, or specification
  • Sample quantity, trial order, or bulk demand
  • Preferred packing form or net weight
  • Destination country or port
  • Required documents or compliance expectations
Storage & Handling

Packaging, Storage, and Handling Notes

Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.

Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.

Supply Support

Sample, Bulk Order and Repeat Supply Support

Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.

For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.

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