Hydroxypinacolone Retinoate (HPR) CAS 893412-73-2

Product Overview

Hydroxypinacolone Retinoate (HPR, CAS 893412-73-2) is a retinoic-acid ester used as a cosmetic formulation ingredient in oil-phase or compatible delivery systems. Its identity and active content must be distinguished from any carrier-based HPR blend.

Unblended HPR and carrier-based HPR grades differ in active content and formulation handling. Compare the HPR content and reporting basis, carrier identity where applicable, assay method and related-substance limits before selecting a grade.

Product Information / Specifications

HPR Assay and Quality Control

For purchasing comparisons, distinguish HPR assay from chromatographic purity and from the percentage of a commercial blend. HPLC can be used to assess HPR and related substances, but an area-percentage result is not automatically the HPR mass fraction in a carrier-containing material. Agree the reporting basis, reference standard, sample preparation and impurity limits for the supplied form. We can provide HPLC chromatograms and method information to support HPR quality evaluation.

Physical & Chemical Properties

• Melting Point: For unblended HPR, the melting range is a grade specification reported in our TDS/COA; it does not describe the behaviour of a carrier-based blend.
• Solubility: HPR requires a compatible solvent or delivery system. For carrier-based grades, the carrier and HPR concentration determine how the material is incorporated into the intended formulation phase.
• Stability: Protect from light, oxygen and heat according to the grade-specific product documentation.

Applications

HPR is used in cosmetic skin-care development targeting the appearance of fine lines and uneven texture. Select the supplied form for the intended phase and evaluate active content, solubility, stability and packaging compatibility in the finished formula.

• Oil-based facial serums with a suitable solvent or delivery system
• Creams and lotions with a compatible oil phase or encapsulated delivery system
• Anhydrous skin-care formulations evaluated for HPR dissolution and stability

In oil-based HPR formulation work, Squalane and Caprylic/Capric Triglyceride (GTCC) are relevant emollient and vehicle candidates. Their use in an HPR-containing formula does not establish that either material alone will dissolve every HPR grade. Check the solvent system, HPR concentration and low-temperature stability in the complete formulation.

Ascorbyl Tetraisopalmitate is an oil-soluble vitamin C derivative used alongside HPR in some cosmetic formulations. It is a complementary formulation ingredient, not an HPR synonym or a dosage-equivalent replacement. Assess the selected grades together for solubility, colour, oxidation and overall formula stability.

Packaging

We specify light-protective packaging for HPR in our quotation, according to the supplied form, quantity and destination.

Storage Conditions

Use the grade-specific storage temperature and retest period; protect the material from light, oxygen and heat in packaging suitable for the supplied form.

Direct sunlight and high-temperature conditions should be avoided to help maintain formulation stability.

Safety Precautions

Use the supplied SDS and workplace controls appropriate to the actual material form and concentration; avoid exposure and protect the material from light, oxygen and heat during handling.

Use appropriate protective equipment when processing HPR. We can provide COA, TDS and SDS for the supplied grade.