Is pure Hydroxypinacolone Retinoate the same as a diluted HPR blend or retinoid complex?

No. Pure HPR is the identified ingredient with CAS 893412-73-2, while a commercial blend may contain HPR at a stated concentration in a carrier system. They cannot be compared or dosed by trade name alone; the active basis and full carrier composition must be confirmed.

Which HPR grade controls should be agreed for a cosmetic formulation?

Confirm identity, assay basis, appearance, colour, related substances and whether the supplied material is pure HPR or a carrier-based blend. The acceptance specification should include the relevant test methods, because an equal stated percentage does not ensure equal active content or formulation behaviour.

Can HPR replace retinol or another retinoid at the same dosage?

No. HPR, retinol and other retinoids are different ingredients with different formulation characteristics. Any replacement should be evaluated in the intended cosmetic formula for compatibility, appearance and stability. It should not be treated as a potency-equivalent substitution based on a similar product position.

Hydroxypinacolone Retinoate (HPR) CAS 893412-73-2

Hydroxypinacolone Retinoate (HPR, CAS 893412-73-2, ECHA List no. 826-245-0) is a retinoic-acid ester used as a cosmetic formulation ingredient in oil-phase or compatible delivery systems. Pure HPR must be distinguished from a carrier-based HPR blend. Confirm HPR active content, carrier, assay, related substances, storage conditions, packaging and required documents for the offered grade.

CAS: 893412-73-2
Synonyms: Hydroxypinacolone Retinoate; HPR; retinoic acid ester
Einecs: No EINECS number assigned; ECHA List No. 826-245-0
Molecular Formula: C26H38O3
Grade: Confirm whether the material is pure HPR or a carrier-based blend, then confirm assay and related substances
Package: Confirm light-protective packaging and storage requirements for the supplied grade

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Product Description

1 Product Overview

2 Product Information / Specifications

3 Physical & Chemical Properties

Product Overview

Hydroxypinacolone Retinoate (HPR, CAS 893412-73-2) is a retinoic-acid ester used as a cosmetic formulation ingredient in oil-phase or compatible delivery systems. Its identity and active content must be distinguished from any carrier-based HPR blend.

A carrier-based HPR blend is not equivalent to pure HPR. Confirm whether the offered material is pure HPR or a blend, then confirm the carrier, active content, assay, related substances, storage conditions and packaging.

Product Information / Specifications

Product Name	Hydroxypinacolone Retinoate
Abbreviation	HPR
CAS No.	893412-73-2
ECHA List No.	826-245-0
Molecular Formula	C26H38O3
Molecular Weight	398.58 g/mol
Appearance	Appearance depends on whether the material is pure HPR or a carrier-based blend; confirm the offered grade
Grade	Confirm whether the material is pure HPR or a carrier-based blend, then confirm assay and related substances
Synonyms	HPR; hydroxypinacolone retinoate; retinoic acid ester

Physical & Chemical Properties

Melting Point: Confirm the grade-specific melting range in the TDS/COA; a value for pure HPR does not apply to a carrier-based blend.
Solubility: Confirm the carrier, solvent compatibility and intended formulation phase for the offered grade.
Stability: Protect from light, oxygen and heat according to the grade-specific product documentation.

Applications

HPR is evaluated as a cosmetic formulation ingredient only after active content, carrier, phase compatibility, stability and destination-market use conditions are confirmed.

Oil-phase or compatible delivery systems for cosmetic formulations
Emulsion, serum or anhydrous prototype stability and compatibility trials
Research formulations comparing pure HPR with carrier-based HPR material
Destination-market formulation work after permitted use and use level are confirmed

Packaging

Confirm light-protective packaging and storage requirements for the supplied grade

Storage Conditions

Use the grade-specific storage temperature and retest period; protect the material from light, oxygen and heat in packaging suitable for the supplied form.

Direct sunlight and high-temperature conditions should be avoided to help maintain formulation stability.

Safety Precautions

Use the supplied SDS and workplace controls appropriate to the actual material form and concentration; avoid exposure and protect the material from light, oxygen and heat during handling.

Appropriate protective equipment should be used during processing. Technical documents such as COA, TDS, and SDS may be provided according to the supplied grade.

FAQ - Technical & Supply Chain

Q:
Is pure Hydroxypinacolone Retinoate the same as a diluted HPR blend or retinoid complex?

A: No. Pure HPR is the identified ingredient with CAS 893412-73-2, while a commercial blend may contain HPR at a stated concentration in a carrier system. They cannot be compared or dosed by trade name alone; the active basis and full carrier composition must be confirmed.
Q:
Which HPR grade controls should be agreed for a cosmetic formulation?

A: Confirm identity, assay basis, appearance, colour, related substances and whether the supplied material is pure HPR or a carrier-based blend. The acceptance specification should include the relevant test methods, because an equal stated percentage does not ensure equal active content or formulation behaviour.
Q:
Can HPR replace retinol or another retinoid at the same dosage?

A: No. HPR, retinol and other retinoids are different ingredients with different formulation characteristics. Any replacement should be evaluated in the intended cosmetic formula for compatibility, appearance and stability. It should not be treated as a potency-equivalent substitution based on a similar product position.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

COA, TDS, SDS/MSDS and packing details are available on request.

Quotation

Send the CAS number, grade, quantity, packing preference and destination.

Sample & Supply

Support is available for samples, trial orders, bulk and repeat supply.

Storage & Shipping

Product-specific conditions are confirmed before order.

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