What is Povidone CAS 9003-39-8?

Povidone, also called polyvinylpyrrolidone or PVP, is a non-ionic water-soluble synthetic polymer made from N-vinyl-2-pyrrolidone. CAS 9003-39-8 identifies the polymer, with general formula (C6H9NO)n, and it is supplied mainly as a white to yellowish-white hygroscopic powder.

What does the K-value of Povidone K30 indicate?

K-value is related to the polymer's average molecular weight and solution viscosity. A K30 grade, typically with K-value 27.0-32.0, represents a medium molecular weight product suited to standard wet granulation, direct compression, film coating, and solubility enhancement applications.

Which applications commonly use Povidone CAS 9003-39-8?

In pharmaceutical formulations it is used as a tablet and capsule binder, film former, stabilizer, and dissolution enhancer for poorly water-soluble actives. It is also used in personal-care products as a film former and viscosity agent, and in industrial systems as a dispersant or steric stabilizer.

Why does Povidone require tightly closed storage?

Povidone is highly hygroscopic and readily absorbs moisture, which can cause powder caking and affect handling or formulation consistency. It should be kept in tightly sealed containers in a cool, dry, well-ventilated area, with normal dust-control measures used during handling.

Povidone CAS 9003-39-8

Povidone (CAS 9003-39-8) is a non-ionic water-soluble synthetic polymer synthesized through the free-radical polymerization of N-vinyl-2-pyrrolidone, serving as a critical functional excipient within the Pharmaceutical API & Intermediates category. Functioning as a high-performance polyvidone matrix, this versatile PVP resin exhibits excellent complexing capabilities, physiological inertness, and film-forming properties, making the poly(1-vinyl-2-pyrrolidone) integral to wet granulation processes and controlled-release solid dosage formulations. Its highly hygroscopic polyvinylpyrrolidone structure provides exceptional adhesive strength and solubility enhancement for poorly water-soluble active chemical ingredients when deployed in standard manufacturing workflows. To support continuous industrial processing schedules, our facility maintains extensive bulk supply capabilities, ensuring consistent molecular weight distribution with customized specifications to meet precise rheological parameters, all supported by competitive factory pricing and comprehensive technical documentation including MSDS, TDS, COA.

CAS: 9003-39-8
Synonyms: Polyvinylpyrrolidone, PVP resin, Polyvidone, Povidonum, Poly(1-vinyl-2-pyrrolidone)
Einecs: 618-363-4
Molecular Formula: (C6H9NO)n
Grade: Pharmaceutical Grade / Industrial Grade
Package: 25kg/drum (Fiber drum with double PE inner liners)

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Product Description

Technical Data

Physicochemical Properties	Standard Specification (Standard K30 Grade)
Appearance	White to yellowish-white hygroscopic powder
K-Value	27.0 – 32.0
pH Value (5% aqueous solution)	3.0 – 7.0
Moisture / Water Content	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual N-vinylpyrrolidone Monomer	≤ 0.001% (10 ppm)
Solubility	Freely soluble in water, ethanol, and chloroform; practically insoluble in ether

Applications

Pharmaceutical Formulation: Functions primarily as a highly effective synthetic polymer binder for tablet and capsule wet granulation, and acts as a dissolution enhancer for low-solubility active pharmaceutical ingredients.
Cosmetic & Personal Care: Utilized as a superior film-forming agent and emulsion stabilizer in hair styling gels, lotions, and color-dispersing formulations.
Industrial Manufacturing: Applied as a dispersant and steric stabilizer in the production of industrial ceramics, advanced coatings, and specialty pigment inks.

For solid-dose formulations requiring an insoluble binder or filler, Microcrystalline Cellulose is a separate excipient with its own grade requirements.

Storage & Safety

Storage Conditions: Povidone is highly hygroscopic. It must be stored in tightly sealed, airtight containers within a cool, dry, and well-ventilated warehouse environment to prevent moisture absorption and caking.
Safety & Handling: While physiologically inert, the handling of fine polymer powders requires standard industrial dust control. Operators must use NIOSH-approved particulate dust masks, safety goggles, and standard protective workwear to mitigate mechanical irritation to the respiratory tract and eyes.

Quality Assurance

Our production lines operate under strict GMP-compliant quality management systems. Each batch undergoes rigorous analytical testing, utilizing High-Performance Liquid Chromatography (HPLC) to ensure residual N-vinylpyrrolidone monomer levels remain strictly below 10 ppm. We continuously monitor the K-value via automated capillary viscometry to guarantee the precise molecular weight distribution and structural consistency required for advanced formulation integrity.

FAQ - Technical & Supply Chain

Q:
What is Povidone CAS 9003-39-8?

A: Povidone, also called polyvinylpyrrolidone or PVP, is a non-ionic water-soluble synthetic polymer made from N-vinyl-2-pyrrolidone. CAS 9003-39-8 identifies the polymer, with general formula (C6H9NO)n, and it is supplied mainly as a white to yellowish-white hygroscopic powder.
Q:
What does the K-value of Povidone K30 indicate?

A: K-value is related to the polymer's average molecular weight and solution viscosity. A K30 grade, typically with K-value 27.0-32.0, represents a medium molecular weight product suited to standard wet granulation, direct compression, film coating, and solubility enhancement applications.
Q:
Which applications commonly use Povidone CAS 9003-39-8?

A: In pharmaceutical formulations it is used as a tablet and capsule binder, film former, stabilizer, and dissolution enhancer for poorly water-soluble actives. It is also used in personal-care products as a film former and viscosity agent, and in industrial systems as a dispersant or steric stabilizer.
Q:
Why does Povidone require tightly closed storage?

A: Povidone is highly hygroscopic and readily absorbs moisture, which can cause powder caking and affect handling or formulation consistency. It should be kept in tightly sealed containers in a cool, dry, well-ventilated area, with normal dust-control measures used during handling.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

COA, TDS, SDS/MSDS and packing details are available on request.

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Sample & Supply

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Storage & Shipping

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