L-Theanine CAS 3081-61-6 is a white crystalline powder that serves as a unique non-protein amino acid for specialized nutritional applications. Within the functional beverage industry, this N-ethyl-L-glutamine acts as a primary additive for flavor modulation and physiological standardization in tea-based formulations. This L-glutamic acid gamma-ethylamide is synthesized or extracted to maintain high chiral purity, ensuring that the theanine maintains its specific molecular interaction within biological systems, while 5-N-ethyl-L-glutamine is widely utilized as a core industrial ingredient in the manufacturing of stress-management supplements. We provide bulk supply with competitive factory pricing for global distribution, ensuring all batches are accompanied by comprehensive MSDS, TDS, COA and offer customized specifications regarding mesh size and purity levels to meet strict regional regulatory requirements.
L-Theanine CAS 3081-61-6
- CAS: 3081-61-6
- Synonyms: N-Ethyl-L-glutamine, Suntheanine, 5-N-Ethyl-L-glutamine, L-Glutamic acid gamma-ethylamide, Theanine
- Einecs: 221-379-0
- Molecular Formula: C7H14N2O3
- Grade: Food Grade / Pharmaceutical Grade
- Package: 25kg/drum or customized bulk packaging
Product Description
Technical Data (Physicochemical Properties)
| Property Category | Parameter | Specification (Standard Export Grade) |
| Physical State | Appearance | White crystalline powder |
| Assay (HPLC) | 98.0% – 102.0% | |
| Specific Rotation | +7.5° to +8.5° | |
| Purity Analysis | Loss on Drying | <= 0.5% |
| Residue on Ignition | <= 0.2% | |
| Chloride (Cl) | <= 0.02% | |
| Contaminants | Heavy Metals (as Pb) | <= 10 ppm |
| Arsenic (As) | <= 1 ppm | |
| Lead (Pb) | <= 1 ppm | |
| Cadmium (Cd) | <= 1 ppm | |
| Solubility | Water Solubility | Soluble (approx. 50 g/L at 25°C) |
| Solvent Solubility | Insoluble in ethanol and ether |
Applications
- Dietary Supplements: Used as a standalone active ingredient or in combination with caffeine for focus-related and cognitive support capsules.
- Functional Beverages: Incorporated into “relaxation drinks” and specialty teas to enhance the “umami” flavor profile and provide nutritional value.
- Pharmaceutical Intermediates: Utilized in research and development for its potential neuroprotective properties and as a building block in specialty chemical synthesis.
- Pet Food Additives: Increasingly used in high-end pet nutrition formulations for calming and behavioral health applications.
Storage & Safety
- Storage: Store in a cool, dark, and dry environment. Keep the container tightly sealed to protect the material from light and moisture. Recommended storage temperature is below 25°C.
- Safety Operations (PPE): Wear a standard dust mask, safety glasses, and protective gloves during bulk handling to avoid inhalation and prolonged skin contact.
- Handling: Maintain good industrial hygiene. Use local exhaust ventilation if the material is handled in a way that generates airborne dust.
Quality Assurance
Our manufacturing facility employs advanced fermentation and synthesis technologies to ensure an enantiomerically pure L-form. Each production lot is subject to High-Performance Liquid Chromatography (HPLC) for assay verification and polarimetry for optical rotation testing. We maintain strict compliance with GMP-aligned quality control standards, providing a full traceability chain for every batch to meet the rigorous safety standards of the international food and health supplement markets.
FAQ - Technical & Supply Chain
-
Q:
How does the CAS 3081-61-6 identity ensure chirality compared to synthetic racemic mixtures?
A: CAS 3081-61-6 specifically designates the L-isomer of theanine. For industrial applications, this distinction is vital as the biological activity and flavor-modulating properties are inherent only to the L-form. Racemic mixtures (D,L-Theanine) carry different identifiers and do not provide the same physiological profile required for functional food and supplement formulations. -
Q:
Is this material stable for use in high-temperature industrial processing like UHT?
A: Yes, L-Theanine demonstrates high thermal stability and remains chemically intact during standard beverage processing techniques such as Pasteurization and Ultra-High Temperature (UHT) treatment. It does not readily decompose at the typical acidic to neutral pH levels (pH 3.0–7.0) common in the functional beverage industry. -
Q:
Is this product intended for industrial raw material use or direct retail?
A: This product is supplied exclusively as a bulk industrial ingredient intended for use in factory-scale manufacturing. It is designed to be formulated by professional chemists and production managers into finished retail products and is not intended for direct consumer use in its concentrated powder form.
Documents and Product Support
For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.
- COA for batch-based quality reference
- TDS for key physical and chemical information
- SDS / MSDS for handling, storage, and safety reference
- Packing information for sample, trial, and bulk orders
- Technical communication based on application and specification requirements
Information to Confirm Before Quotation
Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.
- Product name and CAS number
- Application or intended end use
- Required purity, grade, or specification
- Sample quantity, trial order, or bulk demand
- Preferred packing form or net weight
- Destination country or port
- Required documents or compliance expectations
Packaging, Storage, and Handling Notes
Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.
Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.
Sample, Bulk Order and Repeat Supply Support
Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.
For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.










