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  • Hyaluronic Acid CAS 9067-32-7

Hyaluronic Acid CAS 9067-32-7

Hyaluronic Acid (CAS 9067-32-7), industrially processed and supplied as Sodium Hyaluronate, is a high-molecular-weight glycosaminoglycan utilized primarily as a premier humectant in cosmetic formulations and pharmaceutical viscosupplements. This water-soluble Hyaluronan powder functions by retaining up to 1,000 times its weight in water, providing exceptional hydration and viscoelastic properties in HA based serums and dermal fillers. Unlike animal-derived sources, our fermented Bio-fermentation Hyaluronic Acid ensures high purity and low endotoxin levels, making it a critical Sodium Hyalurate component for medical-grade eye drops and anti-aging skincare. We provide this biopolymer with competitive factory pricing to support global beauty and healthcare manufacturing, guaranteeing bulk supply availability for commercial production. Our facility accommodates customized specifications for molecular weight (from Oligo <3kDa to High MW >2.0MDa), while every shipment is fully documented with MSDS, TDS, COA files to meet strict international standards.

  • CAS: 9067-32-7
  • Synonyms: Sodium Hyaluronate, HA, Hyaluronan, Sodium Hyalurate
  • Einecs: 232-678-0
  • Molecular Formula: (C₁₄H₂₀NNaO₁₁)ₙ
  • Grade: Cosmetic / Pharmaceutical grade
  • Package: 1 kg aluminum foil bag; 10 kg / 25 kg fiber drum, or customized according to customer requirements
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Product Description

Hyaluronic Acid (Sodium Hyaluronate) CAS 9067-32-7 is a high-purity, fermentation-based biopolymer widely used in cosmetics, pharmaceuticals and nutraceuticals. It is valued for its excellent water-binding capacity, biocompatibility and film-forming properties, providing long-lasting moisturization and lubrication in skin, eye and joint applications.

📧 Email: info@industrochem.com – Contact us for COA, molecular weight options and latest bulk prices.

Physicochemical Properties

PropertyTypical Specification
CAS Number9067-32-7
Einecs232-678-0
Molecular Formula(C₁₄H₂₀NNaO₁₁)ₙ
Molecular Weight (polymer)~10 kDa – 3,000 kDa (customizable range)
Assay (dried basis)≥ 95.0%
AppearanceWhite to off-white, free-flowing, odorless powder
SolubilityFreely soluble in water; forms clear to slightly opalescent solution
pH (1% aqueous solution, 25 °C)5.5 – 7.5
Loss on drying≤ 10.0%
Intrinsic / solution viscosityGrade-dependent; from low to very high viscosity
Heavy metals≤ 20 ppm
Protein content≤ 0.03–0.04%
Nucleic acids (A260)≤ 0.5
Microbial limits (TAMC)< 100 CFU/g
OdorOdorless
StabilityStable under recommended storage; sensitive to strong oxidizers

Applications

1. Cosmetics & Personal Care

  • Moisturizing and anti-aging serums
  • Face creams, lotions, masks and eye creams
  • Toners, essences and ampoules
  • Hair care products (conditioners, leave-on treatments)

Key functions:

  • Strong humectant: binds large amounts of water to the stratum corneum
  • Film-forming: creates a breathable, protective layer, improving skin elasticity and smoothness
  • Sensory enhancement: adds slip and richness, especially in water-based systems

2. Pharmaceutical & Medical Uses

  • Ophthalmic solutions, eye drops and intraocular viscoelastic agents
  • Intra-articular injections for joint lubrication and osteoarthritis support
  • Wound dressings, tissue-engineering scaffolds and topical gels

Here, sodium hyaluronate contributes:

  • Lubrication and shock absorption in joints
  • Space-maintaining and protective functions in eye surgery
  • Moist wound-healing environment and cell-friendly matrix support

3. Nutraceuticals & Dietary Supplements

  • Skin beauty and hydration capsules, powders and drinks
  • Joint-health formulations often combined with collagen, chondroitin or MSM

4. Other Uses

  • Biomedical and cell-culture applications as extracellular matrix component
  • Viscosity modifier and stabilizer in specialized formulationsAbcam+1

Storage Conditions

To maintain quality throughout shelf life:

  • Store in a cool, dry, well-ventilated place, away from sources of heat and moisture.
  • Recommended storage temperature: ≤ 25 °C, preferably 2–8 °C for long-term stability.
  • Keep in tightly sealed original packaging; protect from direct sunlight and strong odors.
  • After opening, reseal promptly and consume as soon as possible, or re-pack under dry, inert conditions if necessary.

Safety Precautions

Sodium hyaluronate is generally considered to have low acute toxicity and good biocompatibility, but it should still be handled as an industrial chemical.

Dispose of material in accordance with local regulations and refer to the product’s official SDS for detailed safety and regulatory information.

Avoid creating dust; do not breathe dust or aerosols.

Use appropriate personal protective equipment: gloves, lab coat, safety glasses, dust mask or respirator in dusty environments.

Avoid contact with eyes and prolonged contact with skin.

In case of contact with eyes, rinse immediately with plenty of water and seek medical attention if irritation persists.

In case of accidental ingestion, rinse mouth and seek medical advice if necessary.

Spillage: sweep up carefully to avoid dust, collect in suitable container for disposal, and ventilate area.

FAQ - Technical & Supply Chain

  • Q:

    Does Hyaluronic Acid CAS 9067-32-7 refer to the acid or the sodium salt?

    A: CAS 9067-32-7 identifies Sodium Hyaluronate, the water-soluble sodium salt form of hyaluronic acid. Industrially supplied cosmetic and pharmaceutical powders are normally this stable salt form.
  • Q:

    Which molecular-weight range should I select for Hyaluronic Acid powder?

    A: Choose low-molecular-weight or oligo grades for better penetration and bioactive delivery, and high-molecular-weight grades for stronger film-forming, hydration and lubricating effects. For skin-care formulations, a combination or a mid-range molecular weight is often used.
  • Q:

    How does molecular weight change the behavior of Sodium Hyaluronate in formulations?

    A: High-molecular-weight Sodium Hyaluronate contributes viscosity, barrier protection and long-lasting surface moisture, while lower-molecular-weight material is easier to dissolve and can penetrate more readily. The ideal choice depends on the serum, cream, eye-drop or injection application.
  • Q:

    Is this Hyaluronic Acid powder animal-derived or fermentation-based?

    A: This product is fermentation-based Sodium Hyaluronate, not an animal-derived extract. Bio-fermentation production provides better consistency, lower endotoxin risk and suitability for high-purity cosmetic, pharmaceutical and medical applications.
  • Q:

    What key specifications should be checked for Hyaluronic Acid CAS 9067-32-7?

    A: Confirm molecular-weight range, assay, appearance, pH, loss on drying, protein and heavy-metal limits, intrinsic or solution viscosity, and microbial limits. The grade should match the intended cosmetic, pharmaceutical or dietary use.
  • Q:

    How should Sodium Hyaluronate powder be stored and handled?

    A: Keep it in tightly closed, moisture-protected containers in a cool, dry environment away from strong temperature changes and direct sunlight. Use dust-control measures and appropriate PPE during weighing and transfer.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

COA, TDS, SDS/MSDS and packing details are available on request.

Quotation

Send the CAS number, grade, quantity, packing preference and destination.

Sample & Supply

Support is available for samples, trial orders, bulk and repeat supply.

Storage & Shipping

Product-specific conditions are confirmed before order.

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