What is N-acylsphingosine CAS 179186-46-0?

CAS 179186-46-0 identifies Ceramide 1, also called Ceramide EOP or Ceramide I. It is an ultra-long-chain omega-hydroxy ceramide with the molecular formula C63H125NO6 and a molecular weight near 992.67 g/mol, supplied mainly as a white to off-white cosmetic powder.

How does Ceramide EOP differ from Ceramide 2 or Ceramide NG?

Ceramide EOP contains an ester-linked omega-hydroxy fatty acid and a phytosphingosine backbone, while Ceramide 2 or Ceramide NG is a simpler ceramide with the formula C36H73NO3. They are different sphingolipids with different CAS numbers, functions, and lipid-structuring behavior.

How is Ceramide EOP typically handled in cosmetic formulations?

It is lipophilic and is usually incorporated through a heated oil phase, with a suitable solvent-assisted or pre-dispersed system for uniform distribution. Storage should be in closed containers in a cool, dry environment to protect the waxy powder from heat and moisture.

N-acylsphingosine CAS 179186-46-0

N-acylsphingosine, also called Ceramide 1, Ceramide EOP or Ceramide I, CAS 179186-46-0, is an ultra-long-chain omega-hydroxy ceramide supplied as a skin-identical lipid for cosmetics and personal care. Confirm the required grade and specification, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 179186-46-0
Synonyms: Ceramide 1, Ceramide EOP, Ceramide I, N-acyl-D-erythro-sphingosine, Skin-identical lipid
Einecs: 605-857-4
Molecular Formula: C₆₃H₁₂₅NO₆
Grade: Cosmetic / Industrial Grade
Package: 1kg / aluminum foil bag, 25kg / drum

Request a quote

Share:

Product Description

N-acylsphingosine CAS 179186-46-0 is Ceramide 1, also called Ceramide EOP or Ceramide I, an ultra-long-chain omega-hydroxy ceramide with the formula C₆₃H₁₂₅NO₆ and EINECS 605-857-4.

Synonyms: Ceramide 1; Ceramide EOP; Ceramide I; N-acyl-D-erythro-sphingosine; Skin-identical lipid.

CAS: 179186-46-0.

Molecular formula: C₆₃H₁₂₅NO₆.

It is supplied mainly as a white to off-white cosmetic powder.

Ceramide EOP contributes to the long-periodicity lamellar structure of the stratum corneum.

It helps organize intercellular lipids that reduce transepidermal water loss.

This makes it useful in restorative creams, lotions and barrier-supporting personal care formulations.

It is lipophilic and is usually incorporated through a heated oil phase, with a solvent-assisted or pre-dispersed system for uniform distribution.

The typical purity (HPLC) is about 98.0% or higher, with a melting point of about 88.0-95.0 °C.

It is soluble in hot ethanol and oils, but insoluble in water.

It also serves in the synthesis of specialized lipid delivery systems, liposomal research and bio-mimetic coatings.

Store in closed containers in a cool, dry environment, preferably below 5 °C for long-term stability.

Protect from light and moisture, and keep containers tightly sealed when not in use.

Confirm appearance, purity, melting point, loss on drying, heavy metals and grade as required.

Use suitable eye and skin protection during handling, and wash skin contact with soap and water.

Confirm packaging with the requested quantity and destination requirements.

The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.

For an RFQ, state the intended application, required grade, quantity, packaging, destination and document needs.

FAQ - Technical & Supply Chain

Q:
What is N-acylsphingosine CAS 179186-46-0?

A: CAS 179186-46-0 identifies Ceramide 1, also called Ceramide EOP or Ceramide I. It is an ultra-long-chain omega-hydroxy ceramide with the molecular formula C63H125NO6 and a molecular weight near 992.67 g/mol, supplied mainly as a white to off-white cosmetic powder.
Q:
Why is Ceramide EOP used in skin barrier repair?

A: Ceramide EOP contributes to the long-periodicity lamellar structure of the stratum corneum, helping organize intercellular lipids that reduce transepidermal water loss. This makes it useful in restorative creams, lotions, and barrier-supporting personal care formulations.
Q:
How does Ceramide EOP differ from Ceramide 2 or Ceramide NG?

A: Ceramide EOP contains an ester-linked omega-hydroxy fatty acid and a phytosphingosine backbone, while Ceramide 2 or Ceramide NG is a simpler ceramide with the formula C36H73NO3. They are different sphingolipids with different CAS numbers, functions, and lipid-structuring behavior.
Q:
How is Ceramide EOP typically handled in cosmetic formulations?

A: It is lipophilic and is usually incorporated through a heated oil phase, with a suitable solvent-assisted or pre-dispersed system for uniform distribution. Storage should be in closed containers in a cool, dry environment to protect the waxy powder from heat and moisture.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

Tell us which documents your procurement team needs. Before an order, we will check whether the quoted source can provide them for the offered lot.

Quotation

Send the CAS number, grade, quantity, packing preference and destination.

Sample & Supply

Ask whether samples, trial quantities or repeat orders are possible. We will check each request against the sourced product and current offer.

Storage & Shipping

Product-specific conditions are confirmed before order.

Current Language

Change Language