How is the molecular identity and acylation state of this N-acylsphingosine confirmed?

Each batch is subjected to Carbon-13 and Proton NMR spectroscopy to verify the specific C18 sphingosine backbone and fatty acid chain length, ensuring the substance corresponds strictly to CAS 179186-46-0 and the specified N-acylation profile.

Is this material intended for use in high-temperature industrial emulsification processes?

This product is commonly used in formulations requiring heating phases, as it exhibits a distinct melting range between 88°C and 95°C; however, it is typically applied within a controlled cooling phase or premixed with oil phases to maintain structural integrity within the industrial matrix.

N-acylsphingosine CAS 179186-46-0

N-acylsphingosine, identified by CAS 179186-46-0, is a foundational sphingolipid consisting of a long-chain amino alcohol backbone acylated with a fatty acid, functioning as a primary structural component of the intercellular lipid lamellae in various Cosmetic Raw Materials applications. In industrial synthesis and chemical processing, this Ceramide 2 serves as a critical lipid-replenishing agent, utilizing its molecular polarity and hydrophobicity to facilitate the organization of liquid crystalline structures within complex emulsion systems. As a refined N-stearoylsphingosine, it acts through an interfacial mechanism to modulate viscosity and phase stability in non-aqueous and surfactant-based industrial matrices. This N-acyl-D-erythro-sphingosine is available with competitive factory pricing and customized specifications to meet diverse manufacturing requirements. We provide comprehensive technical documentation including MSDS, TDS, COA for every batch to ensure regulatory compliance and facilitate bulk supply for large-scale production.

CAS: 179186-46-0
Synonyms: Ceramide 2, Ceramide NG, N-stearoylsphingosine, N-acyl-D-erythro-sphingosine, Skin-identical lipid
Einecs: 605-857-4
Molecular Formula: C36H73NO3
Grade: Cosmetic / Industrial Grade
Package: 1kg / aluminum foil bag, 25kg / drum

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Product Description

Technical Data

Property	Specification
Appearance	White to off-white crystalline powder
Purity (HPLC)	>= 98.0%
Melting Point	88.0°C – 95.0°C
Loss on Drying	<= 1.0%
Heavy Metals	<= 10 ppm
Solubility	Soluble in hot ethanol and oils; insoluble in water

Applications

Cosmetic Raw Materials: Primarily used as a key ingredient in skin-barrier repair formulations and hair care conditioning agents.
Pharmaceutical Intermediates: Utilized in the synthesis of specialized lipid delivery systems and liposomal research.
Industrial Chemicals: Employed in the production of bio-mimetic coatings and surface treatment agents requiring lipid-phase stability.

Storage & Safety

Storage: Store in a cool, dry, and well-ventilated warehouse. Keep container tightly sealed, preferably under 5°C for long-term stability. Protect from direct light and moisture.
Safety Operations: Handle with standard industrial hygiene practices. Use Personal Protective Equipment (PPE) including chemical-resistant gloves and safety goggles. Avoid dust inhalation and direct contact with skin or eyes.

Quality Assurance

Our production facility adheres to rigorous quality control protocols. Each batch of N-acylsphingosine undergoes high-resolution HPLC for purity verification and NMR spectroscopy to confirm molecular structure. Our manufacturing environment follows standardized industrial management systems to ensure consistency, traceability, and high-purity output for sensitive industrial applications.

FAQ - Technical & Supply Chain

Q:
How is the molecular identity and acylation state of this N-acylsphingosine confirmed?

A: Each batch is subjected to Carbon-13 and Proton NMR spectroscopy to verify the specific C18 sphingosine backbone and fatty acid chain length, ensuring the substance corresponds strictly to CAS 179186-46-0 and the specified N-acylation profile.
Q:
Is this material intended for use in high-temperature industrial emulsification processes?

A: This product is commonly used in formulations requiring heating phases, as it exhibits a distinct melting range between 88°C and 95°C; however, it is typically applied within a controlled cooling phase or premixed with oil phases to maintain structural integrity within the industrial matrix.

Documents

Documents and Product Support

For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.

COA for batch-based quality reference
TDS for key physical and chemical information
SDS / MSDS for handling, storage, and safety reference
Packing information for sample, trial, and bulk orders
Technical communication based on application and specification requirements

Quotation

Information to Confirm Before Quotation

Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.

Product name and CAS number
Application or intended end use
Required purity, grade, or specification
Sample quantity, trial order, or bulk demand
Preferred packing form or net weight
Destination country or port
Required documents or compliance expectations

Storage & Handling

Packaging, Storage, and Handling Notes

Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.

Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.

Supply Support

Sample, Bulk Order and Repeat Supply Support

Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.

For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.

Contact Form

Use our contact form to send us your questions, suggestions or comments. We will respond as soon as possible.

Product Categories

Tags:

Bioactive Lipid Cosmetic Active Ingredient Life Science Chemical Skin Barrier Ingredient

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