What is Superoxide Dismutase CAS 9054-89-1?

Superoxide Dismutase CAS 9054-89-1 is a metalloenzyme that catalyzes the conversion of superoxide radicals into oxygen and hydrogen peroxide. It is supplied as a stabilized protein or lyophilized powder rather than a simple small-molecule chemical.

How is Superoxide Dismutase activity specified?

SOD is usually specified by enzymatic activity, such as units per milligram or IU/mg, rather than only by purity percentage. Buyers should compare activity, protein content, source, and assay method when evaluating different grades.

Why does SOD need stabilization or encapsulation in cosmetics?

Enzymes can be sensitive to heat, pH, and formulation stress. Encapsulation, liposomal delivery, or chemical modification can help protect SOD activity, improve compatibility, and support better delivery in creams and serums.

What is the difference between cosmetic grade and food grade SOD?

Cosmetic grade is selected for topical antioxidant and skin-care formulations, while food or nutraceutical grade is intended for functional foods and supplements. They may differ in source, activity specification, microbial control, and documentation.

What storage and handling conditions should be followed?

Store SOD powder sealed, cool, dry, and protected from moisture and extreme temperature; refrigerated or frozen storage may be recommended depending on the product. Avoid prolonged exposure to strong oxidizers and maintain cleanliness during weighing and use.

Superoxide Dismutase (SOD) CAS 9054-89-1

Superoxide Dismutase (SOD) (CAS 9054-89-1) is a potent enzymatic antioxidant functioning as the body's primary defense against oxidative stress and free radical damage. Chemically identified as a metalloprotein oxidoreductase, this lyophilized powder acts to catalyze the dismutation of the harmful superoxide radical into oxygen and hydrogen peroxide, effectively neutralizing cellular toxicity. As a highly bioactive Protein scavenger derived typically from microbial fermentation or plant sources, it is extensively integrated into anti-aging skincare, nutraceutical capsules, and functional foods to reduce inflammation and protect DNA from oxidative degradation. We ensure bulk supply capabilities for this material, providing access to competitive factory pricing and customized specifications to meet specific enzymatic activity levels (e.g., 3000 U/mg, 5000 U/mg). Full technical documentation, including MSDS, TDS, COA, is available to support compliance and safety protocols.

CAS: 9054-89-1
Synonyms: SOD, Superoxide oxidoreductase, Orgotein, SOD enzyme
Einecs: 232-943-0
Grade: Cosmetic Grade / Food Grade
Package: 1kg Aluminum Foil Bag, 10kg Carton, or 25kg Drum (Custom packaging available)

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Product Description

Superoxide Dismutase (SOD) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O2−) radical into ordinary molecular oxygen (O2) and hydrogen peroxide (H2O2). It acts as the body’s first line of defense against free radical damage.

Our SOD powder is characterized by high purity and high specific activity (ranging from 3,000 U/g to 50,000 U/g+). Unlike traditional unstable enzymes, our product undergoes specialized stabilization processing, making it suitable for formulation in creams, lotions, and oral supplements. It effectively clears superoxide anion free radicals, delays aging, and regulates immune function.

1 Physicochemical Properties

2 Applications

3 Storage Conditions

4 Safety Precautions

Physicochemical Properties

The following specifications represent our standard Cosmetic/Food Grade export quality (Standard 50,000 U/g specification):

Property	Specification / Value
Appearance	White to Off-white or Pale Yellow Powder
Enzyme Activity	≥ 50,000 U/g (Customizable: 3000 – 100,000 U/g)
Source	Plant Extract (Corn/Yeast) or Microbial Fermentation
Solubility	Easily soluble in water
pH (1% Solution)	6.5 – 7.5
Loss on Drying	≤ 5.0%
Protein Content	≥ 85%
Heavy Metals (as Pb)	≤ 10 ppm
Arsenic (As)	≤ 2 ppm
Total Plate Count	≤ 1000 cfu/g
Stability	High thermal and pH stability (Modified types available)

Applications

SOD is a versatile active ingredient used in various sectors:

Cosmetics & Skincare (Anti-Aging):
- Antioxidant: Scavenges free radicals to delay skin aging and reduce wrinkles.
- Sun Care: Protects skin from UV radiation damage.
- Whitening: Inhibits tyrosinase activity to prevent pigmentation.
- Anti-inflammation: Soothes sensitive skin.
Nutraceuticals & Functional Foods:
- Used in oral supplements (capsules/tablets) to boost immunity, reduce oxidative stress, and improve recovery from fatigue.
Oral Care:
- Added to toothpaste and mouthwash to reduce gingivitis and gum inflammation.
Pharmaceuticals:
- Used as a biochemical raw material for anti-inflammatory drugs.

Storage Conditions

Temperature: For long-term storage, keep at 2-8°C (Refrigerated) or -20°C (Frozen) to maintain maximum enzyme activity.
Short-term: Stable at cool room temperature for shipping, but avoid heat exposure.
Protection: Store in a tightly sealed container, protected from light and moisture.
Shelf Life: 24 months when stored properly at low temperatures.

Safety Precautions

Handling: Enzymes are proteins and may cause sensitization (allergy) by inhalation of dust in susceptible individuals. Avoid breathing dust.
PPE: Wear a dust mask, safety glasses, and gloves during handling.
Skin/Eye Contact: In case of contact, flush generously with water. It is generally non-irritating to skin but standard hygiene applies.
Disposal: Dispose of waste in accordance with local environmental regulations.

FAQ - Technical & Supply Chain

Q:
What is Superoxide Dismutase CAS 9054-89-1?

A: Superoxide Dismutase CAS 9054-89-1 is a metalloenzyme that catalyzes the conversion of superoxide radicals into oxygen and hydrogen peroxide. It is supplied as a stabilized protein or lyophilized powder rather than a simple small-molecule chemical.
Q:
How is Superoxide Dismutase activity specified?

A: SOD is usually specified by enzymatic activity, such as units per milligram or IU/mg, rather than only by purity percentage. Buyers should compare activity, protein content, source, and assay method when evaluating different grades.
Q:
Why does SOD need stabilization or encapsulation in cosmetics?

A: Enzymes can be sensitive to heat, pH, and formulation stress. Encapsulation, liposomal delivery, or chemical modification can help protect SOD activity, improve compatibility, and support better delivery in creams and serums.
Q:
What is the difference between cosmetic grade and food grade SOD?

A: Cosmetic grade is selected for topical antioxidant and skin-care formulations, while food or nutraceutical grade is intended for functional foods and supplements. They may differ in source, activity specification, microbial control, and documentation.
Q:
What storage and handling conditions should be followed?

A: Store SOD powder sealed, cool, dry, and protected from moisture and extreme temperature; refrigerated or frozen storage may be recommended depending on the product. Avoid prolonged exposure to strong oxidizers and maintain cleanliness during weighing and use.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

COA, TDS, SDS/MSDS and packing details are available on request.

Quotation

Send the CAS number, grade, quantity, packing preference and destination.

Sample & Supply

Support is available for samples, trial orders, bulk and repeat supply.

Storage & Shipping

Product-specific conditions are confirmed before order.

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