Superoxide Dismutase (SOD) (CAS 9054-89-1) is a potent enzymatic antioxidant functioning as the body's primary defense against oxidative stress and free radical damage. Chemically identified as a metalloprotein oxidoreductase, this lyophilized powder acts to catalyze the dismutation of the harmful superoxide radical into oxygen and hydrogen peroxide, effectively neutralizing cellular toxicity. As a highly bioactive Protein scavenger derived typically from microbial fermentation or plant sources, it is extensively integrated into anti-aging skincare, nutraceutical capsules, and functional foods to reduce inflammation and protect DNA from oxidative degradation. We ensure bulk supply capabilities for this material, providing access to competitive factory pricing and customized specifications to meet specific enzymatic activity levels (e.g., 3000 U/mg, 5000 U/mg). Full technical documentation, including MSDS, TDS, COA, is available to support compliance and safety protocols.
Superoxide Dismutase (SOD) CAS 9054-89-1
- CAS: 9054-89-1
- Synonyms: SOD, Superoxide oxidoreductase, Orgotein, SOD enzyme
- Einecs: 232-943-0
- Grade: Cosmetic Grade / Food Grade
- Package: 1kg Aluminum Foil Bag, 10kg Carton, or 25kg Drum (Custom packaging available)
Product Description
Superoxide Dismutase (SOD) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O2−) radical into ordinary molecular oxygen (O2) and hydrogen peroxide (H2O2). It acts as the body’s first line of defense against free radical damage.
Our SOD powder is characterized by high purity and high specific activity (ranging from 3,000 U/g to 50,000 U/g+). Unlike traditional unstable enzymes, our product undergoes specialized stabilization processing, making it suitable for formulation in creams, lotions, and oral supplements. It effectively clears superoxide anion free radicals, delays aging, and regulates immune function.
Physicochemical Properties
The following specifications represent our standard Cosmetic/Food Grade export quality (Standard 50,000 U/g specification):
| Property | Specification / Value |
|---|---|
| Appearance | White to Off-white or Pale Yellow Powder |
| Enzyme Activity | ≥ 50,000 U/g (Customizable: 3000 – 100,000 U/g) |
| Source | Plant Extract (Corn/Yeast) or Microbial Fermentation |
| Solubility | Easily soluble in water |
| pH (1% Solution) | 6.5 – 7.5 |
| Loss on Drying | ≤ 5.0% |
| Protein Content | ≥ 85% |
| Heavy Metals (as Pb) | ≤ 10 ppm |
| Arsenic (As) | ≤ 2 ppm |
| Total Plate Count | ≤ 1000 cfu/g |
| Stability | High thermal and pH stability (Modified types available) |
Applications
SOD is a versatile active ingredient used in various sectors:
- Cosmetics & Skincare (Anti-Aging):
- Antioxidant: Scavenges free radicals to delay skin aging and reduce wrinkles.
- Sun Care: Protects skin from UV radiation damage.
- Whitening: Inhibits tyrosinase activity to prevent pigmentation.
- Anti-inflammation: Soothes sensitive skin.
- Nutraceuticals & Functional Foods:
- Used in oral supplements (capsules/tablets) to boost immunity, reduce oxidative stress, and improve recovery from fatigue.
- Oral Care:
- Added to toothpaste and mouthwash to reduce gingivitis and gum inflammation.
- Pharmaceuticals:
- Used as a biochemical raw material for anti-inflammatory drugs.
Storage Conditions
- Temperature: For long-term storage, keep at 2-8°C (Refrigerated) or -20°C (Frozen) to maintain maximum enzyme activity.
- Short-term: Stable at cool room temperature for shipping, but avoid heat exposure.
- Protection: Store in a tightly sealed container, protected from light and moisture.
- Shelf Life: 24 months when stored properly at low temperatures.
Safety Precautions
- Handling: Enzymes are proteins and may cause sensitization (allergy) by inhalation of dust in susceptible individuals. Avoid breathing dust.
- PPE: Wear a dust mask, safety glasses, and gloves during handling.
- Skin/Eye Contact: In case of contact, flush generously with water. It is generally non-irritating to skin but standard hygiene applies.
- Disposal: Dispose of waste in accordance with local environmental regulations.
FAQ - Technical & Supply Chain
-
Q:
Chemically, how is Superoxide Dismutase (SOD) CAS 9054-89-1 defined in the context of bio-actives?
A: Superoxide Dismutase (CAS 9054-89-1) is defined as a class of metalloenzymes that constitute the first line of antioxidant defense, supplied as a stabilized protein powder measured by its catalytic activity units (U/mg) rather than purity percentage. -
Q:
Is this enzyme stable enough for use in cosmetic creams?
A: Yes, modern industrial grades are typically encapsulated or chemically modified (e.g., liposomal SOD) to enhance stability and skin penetration, making them highly effective in anti-wrinkle and sun-repair formulations.
Documents and Product Support
For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.
- COA for batch-based quality reference
- TDS for key physical and chemical information
- SDS / MSDS for handling, storage, and safety reference
- Packing information for sample, trial, and bulk orders
- Technical communication based on application and specification requirements
Information to Confirm Before Quotation
Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.
- Product name and CAS number
- Application or intended end use
- Required purity, grade, or specification
- Sample quantity, trial order, or bulk demand
- Preferred packing form or net weight
- Destination country or port
- Required documents or compliance expectations
Packaging, Storage, and Handling Notes
Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.
Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.
Sample, Bulk Order and Repeat Supply Support
Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.
For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.




