What is 10-Hydroxydecanoic Acid CAS 1679-53-4?

10-Hydroxydecanoic Acid CAS 1679-53-4 is a saturated C10 omega-hydroxy fatty acid with the formula C10H20O3 and molecular weight about 188.26 g/mol. It contains both a terminal hydroxyl group and a carboxylic acid group.

Why is 10-Hydroxydecanoic Acid used in pharmaceutical synthesis?

It is an important bifunctional intermediate used to construct active pharmaceutical ingredients, including idebenone-related compounds. The terminal alcohol and acid groups allow controlled esterification, oxidation, and coupling reactions.

What other synthesis applications use this omega-hydroxy acid?

It is used in the preparation of macrocyclic musk ingredients and derivatives such as 10-hydroxy-2-decylenic acid, also called queen acid. These applications rely on the long-chain difunctional structure for cyclization or chain extension.

What are the key commercial specifications for 10-Hydroxydecanoic Acid?

Typical commercial material is a white to off-white crystalline powder or flakes with assay at least 98.5% by GC, melting point about 75-78 C, low moisture, and acid value in the high 200s to low 300s mg KOH/g.

What storage and solubility considerations are relevant?

It is soluble in ethanol, methanol, ether, and hot water but only slightly soluble in cold water. Store it sealed in a cool, dry place to limit moisture uptake and preserve crystalline quality.

10-Hydroxydecanoic Acid CAS 1679-53-4

10-Hydroxydecanoic Acid (CAS 1679-53-4) is a specialized omega-hydroxy fatty acid functioning as a critical intermediate in the synthesis of pharmaceutical compounds and synthetic musk fragrances. Chemically identified as 10-Hydroxycapric acid, this white crystalline solid acts as a key monomer building block for biocompatible polyesters and a precursor for bio-active pheromone analogs. As a linear Omega-hydroxy acid found naturally in royal jelly, it is widely utilized in organic synthesis to introduce a terminal hydroxyl group into long-chain molecular structures for fine chemical manufacturing. We ensure bulk supply capabilities for this material, providing access to competitive factory pricing and customized specifications to meet specific purity and melting point requirements. Full technical documentation, including MSDS, TDS, COA, is available to support compliance and safety protocols.

CAS: 1679-53-4
Synonyms: 10-Hydroxycapric acid, Omega-hydroxydecanoic acid, 10-Hydroxy decanoic acid, Decanoic acid 10-hydroxy-
Einecs: 216-848-1
Molecular Formula: C10H20O3
Grade: Pharmaceutical Intermediates / Industrial Grade
Package: 25kg Fiber Drum with double PE inner liners

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Product Description

Produced through advanced oxidation and hydrolysis processes, our 10-Hydroxydecanoic Acid appears as a white to off-white crystalline solid. It serves as a vital building block in organic chemistry.

Key Features:

High Purity: Typically ≥ 98.5% by GC, ensuring low impurities for downstream synthesis.
Reactive Functional Groups: Contains both a hydroxyl group and a carboxyl group, allowing for diverse esterification and polymerization reactions.
Stability: Stable under normal storage conditions, with low moisture content.

1 Physicochemical Properties

2 Applications

3 Storage Conditions

4 Safety Precautions

Physicochemical Properties

The following parameters are based on the standard export specification for this chemical intermediate.

Test Item	Specification (Standard)
Appearance	White to off-white crystalline powder or flakes
Assay (GC)	≥ 98.5%
Melting Point	75.0°C – 78.0°C
Moisture (Loss on Drying)	≤ 0.5%
Ash (Residue on Ignition)	≤ 0.1%
Heavy Metals	≤ 10 ppm
Solubility	Soluble in Ethanol, Methanol, Ether, and hot water; Insoluble in cold water
Acid Value	290 – 305 mgKOH/g

Applications

Pharmaceutical Synthesis: The primary application is as a key intermediate for the synthesis of Idebenone (CAS 58186-27-9), a drug used for cognitive disorders and anti-aging treatments.
Fragrance Industry: Used as a raw material to synthesize macrocyclic musk fragrances (similar to musk ketone alternatives) due to its long carbon chain structure.
Polymer Industry: Used in the production of specialized polyesters and plastics where hydroxy-acid monomers are required to modify polymer properties.
Cosmetics: Occasionally used as a surfactant intermediate or skin-conditioning agent precursor in advanced formulations.

Storage Conditions

Temperature: Store in a cool, dry place. Recommended storage temperature is below 30°C.
Environment: Keep container tightly closed in a dry and well-ventilated place.
Protection: Protect from humidity and direct sunlight.
Shelf Life: 24 months when stored in the original sealed container.

Safety Precautions

Health Hazard: Causes skin irritation and serious eye irritation. May cause respiratory irritation if dust is inhaled.
Handling: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed.
PPE: Wear safety glasses with side-shields and protective gloves (Nitrile rubber). Wear a dust mask (N95) when handling powder.
First Aid:
- Eye Contact: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
- Skin Contact: Wash off with soap and plenty of water.

FAQ - Technical & Supply Chain

Q:
What is 10-Hydroxydecanoic Acid CAS 1679-53-4?

A: 10-Hydroxydecanoic Acid CAS 1679-53-4 is a saturated C10 omega-hydroxy fatty acid with the formula C10H20O3 and molecular weight about 188.26 g/mol. It contains both a terminal hydroxyl group and a carboxylic acid group.
Q:
Why is 10-Hydroxydecanoic Acid used in pharmaceutical synthesis?

A: It is an important bifunctional intermediate used to construct active pharmaceutical ingredients, including idebenone-related compounds. The terminal alcohol and acid groups allow controlled esterification, oxidation, and coupling reactions.
Q:
What other synthesis applications use this omega-hydroxy acid?

A: It is used in the preparation of macrocyclic musk ingredients and derivatives such as 10-hydroxy-2-decylenic acid, also called queen acid. These applications rely on the long-chain difunctional structure for cyclization or chain extension.
Q:
What are the key commercial specifications for 10-Hydroxydecanoic Acid?

A: Typical commercial material is a white to off-white crystalline powder or flakes with assay at least 98.5% by GC, melting point about 75-78 C, low moisture, and acid value in the high 200s to low 300s mg KOH/g.
Q:
What storage and solubility considerations are relevant?

A: It is soluble in ethanol, methanol, ether, and hot water but only slightly soluble in cold water. Store it sealed in a cool, dry place to limit moisture uptake and preserve crystalline quality.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

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COA, TDS, SDS/MSDS and packing details are available on request.

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