Octadecenedioic Acid (CAS 20701-68-2) is a long-chain monounsaturated dicarboxylic acid (LCDA) functioning as a potent skin brightening agent in cosmetics and a high-performance monomer in polymer synthesis. Chemically identified as Octadec-9-ene-1,18-dioic acid, this white to off-white powder acts to inhibit melanogenesis by interacting with PPAR receptors and serves as a cross-linking agent in the production of polyamides and polyesters. As a specialized Dioic acid derivative obtained typically via bio-fermentation of oleic acid, it is extensively integrated into advanced skincare formulations for dark spot reduction and into industrial coatings for corrosion inhibition. We ensure bulk supply capabilities for this material, providing access to competitive factory pricing and customized specifications to meet specific purity and acid value requirements. Full technical documentation, including MSDS, TDS, COA, is available to support compliance and safety protocols.
Octadecenedioic Acid CAS 20701-68-2
- CAS: 20701-68-2
- Synonyms: Octadec-9-ene-1,18-dioic acid, 9-Octadecenedioic acid, cis-9-Octadecenedioic acid, (9Z)-Octadecenedioic acid, C18:1 Dioic Acid
- Einecs: 422-260-8
- Molecular Formula: C18H32O4
- Grade: Cosmetic Grade
- Package: 1kg Aluminum Foil Bag / 25kg Fiber Drum
Product Description
Octadecenedioic Acid is produced through a bio-fermentation process using oleic acid (from vegetable oils). It acts as a dual-action agent:
- Skin Brightening: It binds to the Peroxisome Proliferator-Activated Receptor (PPAR) in melanocytes, regulating the transcription of tyrosinase, thereby reducing melanin synthesis more effectively than tyrosinase inhibitors alone.
- Anti-Inflammatory & Anti-Acne: It demonstrates bacteriostatic properties similar to Azelaic Acid but is effective at much lower concentrations.
Why choose Octadecenedioic Acid?
- High Permeability: Its lipophilic nature ensures deep penetration into the epidermis.
- Stability: Excellent thermal and pH stability compared to other whitening agents like Vitamin C or Kojic Acid.
- Safety: Non-cytotoxic and safe for daytime use (non-photosensitizing).
Physicochemical Properties
The following parameters represent standard high-purity Cosmetic Grade specifications.
| Test Item | Specification (Standard) |
|---|---|
| Appearance | White to off-white crystalline powder |
| Odor | Characteristic, slight |
| Assay (GC / HPLC) | ≥ 98.0% |
| Acid Value | 350 – 370 mg KOH/g |
| Melting Point | 85.0°C – 95.0°C |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.5% |
| Heavy Metals (Pb) | ≤ 10 ppm |
| Arsenic (As) | ≤ 2 ppm |
| Solubility | Soluble in Ethanol, Glycols (Butylene Glycol), and Oils; Insoluble in Water |
| Bacterial Count | < 100 CFU/g |
Applications
- Skin Whitening & Brightening: Primary active ingredient in serums, spot correctors, and whitening creams to treat melasma, sun spots, and post-inflammatory hyperpigmentation.
- Anti-Acne Preparations: Used to control sebum production and reduce acne-causing bacteria.
- Anti-Aging: Helps improve skin texture and reduce the appearance of fine lines.
- Deodorants: Due to its antimicrobial properties against odor-causing bacteria.
Formulation Tips:
- Recommended Dosage: 1.0% – 4.0%.
- Incorporation: It is oil-soluble. It should be dissolved in the oil phase or a solvent (like pentylene glycol) at elevated temperatures (approx. 50-60°C) before emulsification.
Storage Conditions
- Temperature: Store in a cool, dry place (preferably < 25°C).
- Light: Protect from direct sunlight and strong light sources.
- Packaging: Keep the inner bag tightly sealed to prevent oxidation and moisture absorption.
- Shelf Life: 24 months from the date of manufacture when stored properly.
Safety Precautions
- Handling: Although it is a cosmetic ingredient, the pure raw material is a concentrated acid. Avoid direct contact with eyes.
- Inhalation: Use a dust mask if handling large quantities of powder to prevent respiratory irritation.
- Skin Contact (Raw Material): Wash with soap and water. It is generally non-irritating in diluted finished products but can be irritating in 100% pure form.
- Eye Contact: Rinse immediately with plenty of water for at least 15 minutes and seek medical advice.
FAQ - Technical & Supply Chain
-
Q:
What is Octadecenedioic Acid CAS 20701-68-2?
A: Octadecenedioic Acid CAS 20701-68-2 is a bio-based C18 unsaturated dicarboxylic acid, also known as cis-9-octadecenedioic acid or octadec-9-ene-1,18-dioic acid. Its molecular formula is C18H32O4 and its INCI name is OCTADECENEDIOIC ACID. -
Q:
How does it compare with azelaic acid in skin-brightening applications?
A: It is structurally related to azelaic acid and is studied in cosmetics for skin brightening, conditioning, and sebum-related care through PPAR-related pathways. It should be described as a cosmetic ingredient rather than as a medical treatment. -
Q:
Can cosmetic grade and polymer grade Octadecenedioic Acid be used interchangeably?
A: Not automatically. Cosmetic grade prioritizes purity, assay, heavy-metal limits, and ingredient documentation, while polymer grade may be specified around acid value, color, moisture, and reactivity for resin synthesis. -
Q:
What key specifications should formulators check for cosmetic use?
A: Common checks include appearance, assay of at least 98%, acid value, melting point, loss on drying, residue on ignition, and heavy metals. Batch-specific documentation should match the intended formulation and market requirements. -
Q:
What industrial uses benefit from the C18 unsaturated diacid structure?
A: It is used as a renewable monomer or modifier in polyesters, polyamides, alkyd resins, adhesives, and powder-coating systems. The long C18 chain and cis double bond can improve flexibility, low-temperature behavior, and hydrophobic compatibility.
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