What is VBE Vanillyl Butyl Ether CAS 82654-98-6?

VBE Vanillyl Butyl Ether CAS 82654-98-6 is a synthetic warming and sensorial cosmetic ingredient. Its INCI name is Vanillyl Butyl Ether, and its chemical name is 4-(butoxymethyl)-2-methoxyphenol, with the molecular formula C12H18O3 and molecular weight 210.27 g/mol. It is normally supplied as a colorless to pale yellow liquid.

How does Vanillyl Butyl Ether create a warming effect compared with capsaicin?

It interacts with the TRPV1 sensory pathway in the skin, producing a perception of warmth rather than directly heating tissue. Compared with capsaicin, it is generally considered much less irritating and offers a more balanced, cosmetic-friendly warming sensation for leave-on products.

What cosmetic applications is VBE suitable for?

VBE is commonly used in body-shaping and slimming creams, anti-cellulite lotions, warming massage products, scalp and hair-care formulations, foot-care products, and fragrance or oral-care applications. It works as an oil-soluble sensorial active that can be incorporated into emulsion, oil, or solvent-based systems.

What are the key formulation properties of Vanillyl Butyl Ether?

It is soluble in ethanol, propylene glycol, oils, and most organic solvents, while it is only slightly soluble or practically insoluble in water. Typical values include a boiling point around 241 C, density around 1.057 g/mL at 25 C, refractive index about 1.511-1.521 at 20 C, and a flash point above 100 C.

What safety and handling points should formulators confirm before use?

Formulators should treat VBE as a possible serious eye irritant and weak skin sensitizer; some users may develop an allergic skin reaction. Avoid claims that it is non-irritating or suitable for everyone, and use appropriate skin patch testing and regulatory review for each finished formulation.

VBE Vanillyl Butyl Ether CAS 82654-98-6

VBE Vanillyl Butyl Ether, CAS 82654-98-6, is a synthetic warming sensorial active supplied for slimming creams, anti-cellulite lotions, topical analgesics, lip plumpers, warming massage products and hair care. Confirm the required purity and grade, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 82654-98-6
Synonyms: 4-(Butoxymethyl)-2-methoxyphenol, Vanillyl butyl ether, Butyl vanillyl ether, VBE warming agent
Einecs: 444-010-7
Molecular Formula: C₁₂H₁₈O₃
Grade: Cosmetic Grade / Food Grade
Package: 1kg Aluminum Bottle, 5kg, or 25kg Plastic Drum

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Product Description

VBE Vanillyl Butyl Ether, CAS 82654-98-6, is a synthetic warming and sensorial cosmetic ingredient.

Synonyms: 4-(Butoxymethyl)-2-methoxyphenol; Vanillyl butyl ether; Butyl vanillyl ether; VBE warming agent.

CAS: 82654-98-6.

Its chemical name is 4-(butoxymethyl)-2-methoxyphenol and its molecular weight is 210.27 g/mol.

It is normally supplied as a colorless to pale-yellow liquid with a weak vanilla-like odor.

It has a GC purity of not less than 98.0% standard or 99.0% premium, and a refractive index of about 1.511–1.521 at 20 °C.

It has a boiling point of about 241 °C and a flash point above 100 °C.

It is soluble in oil, ethanol, propylene glycol and most organic solvents, and only slightly soluble in water.

It interacts with the TRPV1 sensory pathway to produce a perception of warmth without directly heating tissue.

It is used in body-shaping and slimming creams, anti-cellulite lotions and warming massage products.

It is used in topical analgesic patches, ointments and muscle-rub gels for heat therapy.

It is used in lip plumpers, glosses, scalp treatments and foot-bath products.

It is approved as a flavoring agent, FEMA 3796, to provide vanilla notes and heat sensation.

Confirm appearance, odor, GC purity, refractive index, specific gravity, acid value, APHA color, boiling point, flash point and solubility.

Store below 25 °C in tightly sealed containers, preferably under nitrogen blanketing if opened, and do not freeze.

Protect from direct sunlight and strong UV sources, as the product can turn yellow if oxidized.

Confirm packaging with the requested quantity and destination requirements.

The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.

For an RFQ, state the intended use, required purity and grade, quantity, packaging, destination and document needs.

FAQ - Technical & Supply Chain

Q:
What is VBE Vanillyl Butyl Ether CAS 82654-98-6?

A: VBE Vanillyl Butyl Ether CAS 82654-98-6 is a synthetic warming and sensorial cosmetic ingredient. Its INCI name is Vanillyl Butyl Ether, and its chemical name is 4-(butoxymethyl)-2-methoxyphenol, with the molecular formula C12H18O3 and molecular weight 210.27 g/mol. It is normally supplied as a colorless to pale yellow liquid.
Q:
How does Vanillyl Butyl Ether create a warming effect compared with capsaicin?

A: It interacts with the TRPV1 sensory pathway in the skin, producing a perception of warmth rather than directly heating tissue. Compared with capsaicin, it is generally considered much less irritating and offers a more balanced, cosmetic-friendly warming sensation for leave-on products.
Q:
What cosmetic applications is VBE suitable for?

A: VBE is commonly used in body-shaping and slimming creams, anti-cellulite lotions, warming massage products, scalp and hair-care formulations, foot-care products, and fragrance or oral-care applications. It works as an oil-soluble sensorial active that can be incorporated into emulsion, oil, or solvent-based systems.
Q:
What are the key formulation properties of Vanillyl Butyl Ether?

A: It is soluble in ethanol, propylene glycol, oils, and most organic solvents, while it is only slightly soluble or practically insoluble in water. Typical values include a boiling point around 241 C, density around 1.057 g/mL at 25 C, refractive index about 1.511-1.521 at 20 C, and a flash point above 100 C.
Q:
What safety and handling points should formulators confirm before use?

A: Formulators should treat VBE as a possible serious eye irritant and weak skin sensitizer; some users may develop an allergic skin reaction. Avoid claims that it is non-irritating or suitable for everyone, and use appropriate skin patch testing and regulatory review for each finished formulation.

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