What is L-Tyrosine CAS 60-18-4?

L-Tyrosine CAS 60-18-4 is an aromatic amino acid with the molecular formula C9H11NO3, molecular weight about 181.19 g/mol, and EINECS 200-460-4. It is supplied as a white to off-white crystalline powder and is also known as L-4-hydroxyphenylalanine or 3-(4-hydroxyphenyl)-L-alanine.

Why is L-Tyrosine used in nootropic and cognitive-health supplements?

L-Tyrosine is a precursor for catecholamine neurotransmitters such as dopamine, norepinephrine, and epinephrine. In nootropic formulas it is used to support mental alertness, working memory, and cognitive performance under stress, fatigue, or demanding conditions.

How is L-Tyrosine used in sports nutrition and pre-workout products?

In sports nutrition, L-Tyrosine is added to support focus, motivation, and mental drive during intense training. Unlike amino acids aimed mainly at muscle tissue, it is used for brain-facing benefits and to help maintain cognitive performance during prolonged exercise.

What are the typical food/pharma-grade specifications for L-Tyrosine?

Typical specifications include a white to off-white crystalline powder, assay of 98.5-101.5% on a dry basis, loss on drying at or below 0.30%, and isoelectric point around 5.66. It is usually tested against USP, EP, AJI, or FCC standards depending on the intended market.

Why is L-Tyrosine solubility an important formulation consideration?

L-Tyrosine is very slightly soluble in water, roughly 0.45 g/L at 25 C, but dissolves in dilute mineral acids or alkaline solutions. This makes it more practical in capsules, tablets, powders, or pH-adjusted systems than in high-concentration neutral liquid beverages.

Can L-Tyrosine be used in cosmetics and personal care?

Yes, L-Tyrosine is used in cosmetics and personal care formulations where amino-acid-based ingredients support skin or hair product concepts. The grade, purity, and microbial quality should be matched to the cosmetic application and regional requirements.

L-Tyrosine CAS 60-18-4

L-Tyrosine, also called L-4-hydroxyphenylalanine or (S)-tyrosine, CAS 60-18-4, is a white to off-white crystalline amino acid supplied in food or pharma grade. Confirm the required grade and specification, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 60-18-4
Synonyms: (S)-Tyrosine, L-4-Hydroxyphenylalanine, (S)-alpha-Amino-4-hydroxybenzenepropanoic acid, 3-(4-Hydroxyphenyl)-L-alanine, L-beta-(p-Hydroxyphenyl)alanine
Einecs: 200-460-4
Molecular Formula: C₉H₁₁NO₃
Grade: Food/Pharma Grade
Package: 25kg/bag (Plastic woven bag with PE liner) or 500kg/1000kg Jumbo Bag.

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Product Description

L-Tyrosine CAS 60-18-4 is an aromatic amino acid, also known as L-4-hydroxyphenylalanine, with molecular formula C9H11NO3, molecular weight about 181.19 and EINECS 200-460-4.

Synonyms: (S)-Tyrosine; L-4-Hydroxyphenylalanine; (S)-alpha-Amino-4-hydroxybenzenepropanoic acid; 3-(4-Hydroxyphenyl)-L-alanine; L-beta-(p-Hydroxyphenyl)alanine.

CAS: 60-18-4.

It has the molecular formula C9H11NO3 and a molecular weight of about 181.19 g/mol.

It appears as a white to off-white crystalline powder or fine needles with little to no odor.

A typical specification includes assay of 98.5–101.5% on a dry basis, loss on drying of at most 0.30% and an isoelectric point of about 5.66.

It is only slightly soluble in water (about 0.45 g/L at 25 °C) but dissolves in dilute mineral acids or alkaline solutions.

In nootropic and cognitive-health formulas it acts as a precursor of catecholamine neurotransmitters such as dopamine, norepinephrine and epinephrine.

In sports nutrition it is used to support focus, motivation and mental drive during intense or prolonged training.

In cosmetics and personal care it is used in amino-acid-based skin and hair product concepts.

In research and cell culture it is used as a medium component and as a precursor for neurotransmitter studies.

It is sensitive to light; prolonged exposure to sunlight or strong artificial light can discolor the powder slightly yellow.

Store in a cool, dry, dark place, typically below 25 °C, in opaque or airtight packaging to prevent discoloration and moisture pickup.

It is not highly hygroscopic, but moisture can promote microbial growth, so keep inner liners sealed after opening.

Confirm appearance, assay, loss on drying, heavy metals, microbial limits, specific rotation and residual solvent limits as required.

Use dust masks or respirators and eye protection during handling, and wash skin contact with soap and water.

Confirm packaging with the requested quantity and destination requirements.

The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.

For an RFQ, state the intended use, required grade and specification, quantity, packaging, destination and document needs.

FAQ - Technical & Supply Chain

Q:
What is L-Tyrosine CAS 60-18-4?

A: L-Tyrosine CAS 60-18-4 is an aromatic amino acid with the molecular formula C9H11NO3, molecular weight about 181.19 g/mol, and EINECS 200-460-4. It is supplied as a white to off-white crystalline powder and is also known as L-4-hydroxyphenylalanine or 3-(4-hydroxyphenyl)-L-alanine.
Q:
Why is L-Tyrosine used in nootropic and cognitive-health supplements?

A: L-Tyrosine is a precursor for catecholamine neurotransmitters such as dopamine, norepinephrine, and epinephrine. In nootropic formulas it is used to support mental alertness, working memory, and cognitive performance under stress, fatigue, or demanding conditions.
Q:
How is L-Tyrosine used in sports nutrition and pre-workout products?

A: In sports nutrition, L-Tyrosine is added to support focus, motivation, and mental drive during intense training. Unlike amino acids aimed mainly at muscle tissue, it is used for brain-facing benefits and to help maintain cognitive performance during prolonged exercise.
Q:
What are the typical food/pharma-grade specifications for L-Tyrosine?

A: Typical specifications include a white to off-white crystalline powder, assay of 98.5-101.5% on a dry basis, loss on drying at or below 0.30%, and isoelectric point around 5.66. It is usually tested against USP, EP, AJI, or FCC standards depending on the intended market.
Q:
Why is L-Tyrosine solubility an important formulation consideration?

A: L-Tyrosine is very slightly soluble in water, roughly 0.45 g/L at 25 C, but dissolves in dilute mineral acids or alkaline solutions. This makes it more practical in capsules, tablets, powders, or pH-adjusted systems than in high-concentration neutral liquid beverages.
Q:
Can L-Tyrosine be used in cosmetics and personal care?

A: Yes, L-Tyrosine is used in cosmetics and personal care formulations where amino-acid-based ingredients support skin or hair product concepts. The grade, purity, and microbial quality should be matched to the cosmetic application and regional requirements.

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