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    HomeProductsLife ScienceFood AdditivesL-Tyrosine CAS 60-18-4
    • L-Tyrosine CAS 60-18-4

    L-Tyrosine CAS 60-18-4

    L-Tyrosine CAS 60-18-4 is a non-essential amino acid chemically defined as (S)-2-amino-3-(4-hydroxyphenyl)propanoic acid, functioning primarily as a critical precursor for the biosynthesis of catecholamines and thyroid hormones in biological systems. Also known as L-4-Hydroxyphenylalanine, this crystalline solid is utilized to formulate specialized parenteral nutrition solutions and serves as a starting material in the synthesis of pharmaceutical actives and melanin-related polymers. We provide professional access to this material with competitive factory pricing and the ability to meet customized specifications for various manufacturing requirements. Our commitment to technical transparency ensures that every shipment is accompanied by comprehensive MSDS, TDS, COA documentation to support your quality assurance protocols, and we maintain capacity for consistent bulk supply to facilitate large-scale industrial operations.

    • CAS: 60-18-4
    • Synonyms: (S)-Tyrosine, L-4-Hydroxyphenylalanine, (S)-alpha-Amino-4-hydroxybenzenepropanoic acid, 3-(4-Hydroxyphenyl)-L-alanine, L-beta-(p-Hydroxyphenyl)alanine
    • Einecs: 200-460-4
    • Molecular Formula: C9H11NO3
    • Grade: Food/Pharma Grade
    • Package: 25kg/bag (Plastic woven bag with PE liner) or 500kg/1000kg Jumbo Bag.
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    Product Description

    1 Physical & Chemical Properties
    2 Key Application Fields
    2.1 1. Nootropics and Cognitive Health
    2.2 2. Sports Nutrition (Pre-Workout)
    2.3 3. Cosmetics and Personal Care
    2.4 4. Pharmaceutical Intermediates
    3 Safety and Precautionary Measures
    4 Storage and Handling Conditions

    Physical & Chemical Properties

    L-Tyrosine is an aromatic amino acid. It appears as fine, white silk-like crystals or crystalline powder.

    PropertySpecification / Description
    Product NameL-Tyrosine
    CAS Number60-18-4
    Molecular FormulaC9H11NO3
    Molecular Weight181.19 g/mol
    AppearanceWhite to off-white crystalline powder
    Assay98.5% – 101.5% (Dry Basis)
    SolubilityVery slightly soluble in water; Soluble in dilute mineral acids and alkaline solutions
    pH5.66 (Isoelectric point)
    Loss on Drying≤ 0.30%
    Production StandardUSP / EP / AJI / FCC

    Key Application Fields

    1. Nootropics and Cognitive Health

    This is the fastest-growing sector for L-Tyrosine. It is used to support mental alertness and working memory, particularly under stressful conditions (cold, fatigue, sleep deprivation). It replenishes catecholamine neurotransmitters that get depleted during stress.

    2. Sports Nutrition (Pre-Workout)

    Unlike BCAAs which target muscle tissue, L-Tyrosine is added to pre-workout formulas for the brain. It helps athletes maintain “laser focus” and motivation during intense training sessions, preventing the feeling of mental crash.

    3. Cosmetics and Personal Care

    L-Tyrosine is a precursor to melanin (the pigment in skin). It is often used in:

    • Tanning Accelerators: To help speed up the natural tanning process.
    • Hair Care: To protect hair integrity and color.

    4. Pharmaceutical Intermediates

    It serves as a starting material for the synthesis of various pharmaceutical drugs, including those for thyroid disorders and Parkinson’s disease treatments.

    Safety and Precautionary Measures

    While L-Tyrosine is a dietary ingredient, handling the bulk raw material requires care.

    • Dust Hazard: As a fine powder, it can create dust. Ensure adequate ventilation in the weighing and blending areas to prevent dust accumulation.
    • Respiratory Protection: Inhalation of dust may cause irritation to the respiratory tract. Workers should wear N95 dust masks.
    • Contraindications (Medical): While safe for handling, formulators should be aware that L-Tyrosine can interact with MAOI inhibitors (a class of antidepressants) and thyroid medication.
    • Skin/Eye Contact: Standard safety goggles and gloves should be worn. If contact occurs, flush with water.

    Storage and Handling Conditions

    L-Tyrosine is relatively stable compared to some other amino acids, but it is sensitive to light.

    1. Light Protection: Prolonged exposure to sunlight or strong artificial light can cause the powder to discolor (turning slightly yellow). It must be stored in opaque containers or dark warehouses.
    2. Moisture: Keep in a dry environment. Although it is not highly hygroscopic, moisture can promote microbial growth.
    3. Packaging: Standard export packaging is typically 25kg fiber drums with double polyethylene liners. Drums are preferred over bags to protect the crystal structure and prevent light exposure.
    4. Temperature: Store at room temperature (below 25°C/77°F).

    FAQ - Technical & Supply Chain

    • Q:

      Is standard L-Tyrosine (CAS 60-18-4) suitable for high-concentration liquid beverage formulations?

      A: Typically, no. Standard L-Tyrosine has very low solubility in water (approx. 0.45 g/L at 25°C). For industrial applications requiring high-concentration liquid stability (such as ready-to-drink functional beverages), formulators often substitute this material with N-Acetyl-L-Tyrosine (NALT) or utilize specific pH adjustment techniques to prevent precipitation.
    • Q:

      Does this grade contain animal-derived byproducts?

      A: Our industrial supply of L-Tyrosine is typically produced via fermentation processes using plant-based glucose sources (corn or tapioca). This production method ensures the material is free from avian or porcine contaminants, meeting the strict traceability requirements for vegetarian and kosher-certified downstream products.
    Documents

    Documents and Product Support

    For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.

    • COA for batch-based quality reference
    • TDS for key physical and chemical information
    • SDS / MSDS for handling, storage, and safety reference
    • Packing information for sample, trial, and bulk orders
    • Technical communication based on application and specification requirements
    Quotation

    Information to Confirm Before Quotation

    Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.

    • Product name and CAS number
    • Application or intended end use
    • Required purity, grade, or specification
    • Sample quantity, trial order, or bulk demand
    • Preferred packing form or net weight
    • Destination country or port
    • Required documents or compliance expectations
    Storage & Handling

    Packaging, Storage, and Handling Notes

    Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.

    Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.

    Supply Support

    Sample, Bulk Order and Repeat Supply Support

    Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.

    For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.

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    Amino Acid Life Science Chemical Nutritional Ingredient Pharmaceutical Ingredient

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