What is Citicoline Sodium CAS 33818-15-4?

Citicoline Sodium CAS 33818-15-4 is the sodium salt of cytidine 5'-diphosphocholine, also known as CDP-Choline Sodium. It has molecular formula C14H25N4NaO11P2, molecular weight about 510.31, and EINECS number 251-689-1.

How does Citicoline Sodium differ from citicoline free base?

Citicoline Sodium is the sodium salt form registered as CAS 33818-15-4, while citicoline free base is commonly listed as CAS 987-78-0. The sodium salt form is used in many pharmaceutical and supplement applications because it is highly water-soluble and convenient for aqueous formulations.

What is the difference between the injection and oral/food grades?

The injection grade carries tighter microbiological control, with bacterial endotoxins below 0.5 EU/mg. The oral/food grade is controlled for oral-use contaminants such as total plate count at or below 1000 cfu/g, while both grades use the same citicoline sodium CAS 33818-15-4 base identity.

How soluble is Citicoline Sodium, and how should it be stored?

Citicoline Sodium is freely soluble in water, with reported laboratory solubility around 200 mg/mL. It is highly hygroscopic, so it should be kept tightly sealed and stored in a cool, dry area protected from moisture; the offered packaging uses low-permeability liners to reduce moisture pickup.

Citicoline Sodium CAS 33818-15-4

Citicoline Sodium, also called CDP-Choline Sodium, CAS 33818-15-4, is a water-soluble CDP-choline source supplied for pharmaceutical and nutraceutical formulations. Confirm the required grade and specification, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 33818-15-4
Synonyms: CDP-Choline Sodium, Cytidine 5'-diphosphocholine sodium salt, Citicoline sodium salt, Cytidine 5'-(trihydrogen diphosphate) P'-(2-(trimethylammonio)ethyl) ester sodium salt
Einecs: 251-689-1
Molecular Formula: C₁₄H₂₅N₄NaO₁₁P₂
Grade: Pharmaceutical Grade (Injection/Oral) / Food Grade
Package: 1kg/Alu-tin, 5kg/Drum, or 25kg/Fiber Drum (with double low-permeability PE liners).

Request a quote

Share:

Product Description

Citicoline Sodium CAS 33818-15-4 is the sodium salt of cytidine 5′-diphosphocholine, also known as CDP-Choline Sodium.

Synonyms: CDP-Choline Sodium; Cytidine 5′-diphosphocholine sodium salt; Citicoline sodium salt.

CAS: 33818-15-4.

It has the molecular formula C14H25N4NaO11P2 and a molecular weight of 510.31 g/mol.

It appears as a white or off-white crystalline powder.

It is freely soluble in water, with reported solubility around 200 mg/mL.

A 1% aqueous solution has a pH of about 6.0–7.5.

It has a specific rotation of about +10.0° to +12.0°.

It is highly hygroscopic, so it must be kept tightly sealed and protected from moisture.

The sodium salt form is used in many pharmaceutical and supplement applications because it is highly water-soluble.

It is used as a CDP-choline source in pharmaceutical, nutraceutical and related research formulations.

It supports phospholipid synthesis and supplies choline for acetylcholine metabolism.

A typical specification includes assay of 98.0–102.0% on a dry basis and loss on drying of at most 5.0%.

Related substances, heavy metals, arsenic, bacterial endotoxins and total plate count are controlled by grade.

Confirm appearance, assay, pH, specific rotation, loss on drying, related substances, heavy metals and microbiological limits.

Store tightly sealed in a cool, dry area protected from moisture; low-permeability liners reduce moisture pickup.

Confirm packaging with the requested quantity and destination requirements.

The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.

For an RFQ, state the intended use, required grade and specification, quantity, packaging, destination and document needs.

FAQ - Technical & Supply Chain

Q:
What is Citicoline Sodium CAS 33818-15-4?

A: Citicoline Sodium CAS 33818-15-4 is the sodium salt of cytidine 5'-diphosphocholine, also known as CDP-Choline Sodium. It has molecular formula C14H25N4NaO11P2, molecular weight about 510.31, and EINECS number 251-689-1.
Q:
How does Citicoline Sodium differ from citicoline free base?

A: Citicoline Sodium is the sodium salt form registered as CAS 33818-15-4, while citicoline free base is commonly listed as CAS 987-78-0. The sodium salt form is used in many pharmaceutical and supplement applications because it is highly water-soluble and convenient for aqueous formulations.
Q:
What are the main applications of Citicoline Sodium?

A: Citicoline Sodium is used as a CDP-choline source in pharmaceutical, nutraceutical, and related research formulations. It supports phospholipid synthesis and supplies choline for acetylcholine metabolism, with common application directions in cognitive, neuroprotective, and ocular-health products.
Q:
What is the difference between the injection and oral/food grades?

A: The injection grade carries tighter microbiological control, with bacterial endotoxins below 0.5 EU/mg. The oral/food grade is controlled for oral-use contaminants such as total plate count at or below 1000 cfu/g, while both grades use the same citicoline sodium CAS 33818-15-4 base identity.
Q:
How soluble is Citicoline Sodium, and how should it be stored?

A: Citicoline Sodium is freely soluble in water, with reported laboratory solubility around 200 mg/mL. It is highly hygroscopic, so it should be kept tightly sealed and stored in a cool, dry area protected from moisture; the offered packaging uses low-permeability liners to reduce moisture pickup.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

Tell us which documents your procurement team needs. Before an order, we will check whether the quoted source can provide them for the offered lot.

Quotation

Send the CAS number, grade, quantity, packing preference and destination.

Sample & Supply

Ask whether samples, trial quantities or repeat orders are possible. We will check each request against the sourced product and current offer.

Storage & Shipping

Product-specific conditions are confirmed before order.

Current Language

Change Language