Nicotinamide Riboside Chloride, often called NR-Cl, CAS 23111-00-4, is a crystalline NAD+ precursor ingredient supplied for dietary supplements and pharmaceutical intermediates. Confirm the required grade and specification, then request a quotation with COA/TDS/SDS for bulk supply.
Nicotinamide Riboside Chloride NR-Cl CAS 23111-00-4
- CAS: 23111-00-4
- Synonyms: NR-Cl, Nicotinamide riboside salt, 1-(beta-D-Ribofuranosyl)nicotinamide chloride, Nicotinamide beta-D-riboside chloride
- Einecs: 200-184-4
- Molecular Formula: C₁₁H₁₅ClN₂O₅
- Grade: Food Grade / Pharmaceutical Intermediate
- Package: 1kg/Alu-tin, 5kg/Carton, or 25kg/Drum (Cold Chain recommended).
Product Description
Nicotinamide Riboside Chloride, often called NR chloride or NR-Cl, CAS 23111-00-4, is the chloride salt of nicotinamide riboside, a pyridine-nucleoside form of vitamin B3.
Synonyms: NR-Cl; Nicotinamide riboside salt; 1-(beta-D-Ribofuranosyl)nicotinamide chloride; Nicotinamide beta-D-riboside chloride.
CAS: 23111-00-4.
It has the molecular formula C11H15ClN2O5 and a molecular weight of 290.70 g/mol.
It is a white to light-yellow crystalline powder.
It has an acidic aqueous pH of about 2.0–4.0 and a specific rotation of about +41° to +45°.
The chloride salt form gives nicotinamide riboside improved crystalline stability and easier handling compared with the free base.
It is still moisture-sensitive, so sealed packaging and controlled storage remain important.
It is used as a raw material for NAD+ precursor products, including dietary supplements, functional foods and research formulations.
It can also serve as a pharmaceutical intermediate, but it is a raw ingredient and is not supplied as a finished therapeutic product.
A typical specification includes HPLC purity of at least 98%, water content by Karl Fischer of at most 1.0% and residual solvent limits.
Heavy metals, lead, arsenic, mercury and microbial limits are controlled to meet typical food and pharmaceutical requirements.
It has a naturally sour or bitter taste, which is normal for this chloride salt.
Food and pharmaceutical grades allow buyers to choose a purity and testing profile suitable for the intended process.
Confirm appearance, HPLC purity, water content, pH, specific rotation, residual solvents, heavy metals and microbial limits.
Keep sealed, protected from light and moisture, and store under cool conditions; cold-chain transport is recommended for larger or long-distance orders.
Confirm packaging with the requested quantity and destination requirements.
The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.
For an RFQ, state the intended use, required grade and specification, quantity, packaging, destination and document needs.
FAQ - Technical & Supply Chain
-
Q:
What is Nicotinamide Riboside Chloride CAS 23111-00-4?
A: Nicotinamide Riboside Chloride, often called NR chloride or NR-Cl, is the chloride salt of nicotinamide riboside, a pyridine-nucleoside form of vitamin B3. It has the molecular formula C11H15ClN2O5, molecular weight about 290.70 g/mol, CAS 23111-00-4 and EINECS 200-184-4. -
Q:
Why is the chloride salt form used instead of the free base?
A: The chloride salt form gives nicotinamide riboside improved crystalline stability and easier handling compared with the free base. It is still moisture-sensitive, so sealed packaging and controlled storage remain important even though the salt form is more stable. -
Q:
What is Nicotinamide Riboside Chloride used for?
A: NR chloride is used as a raw material for NAD+ precursor products, including dietary supplements, functional foods and research formulations. It can also serve as a pharmaceutical intermediate, but it is a raw ingredient and is not supplied as a finished therapeutic product. -
Q:
What are the key specifications for food or pharmaceutical-grade NR chloride?
A: Typical checks include a white to light-yellow crystalline appearance, HPLC purity of at least 98%, water content by Karl Fischer, acidic aqueous pH, specific rotation, residual solvents and heavy-metal limits. Buyers should select the grade and specification that match the final product and destination requirements. -
Q:
How should Nicotinamide Riboside Chloride be stored and shipped?
A: NR chloride should be kept sealed, protected from light and moisture, and stored under cool conditions; cold-chain transport is recommended for larger or long-distance orders. The current offer uses 1 kg aluminum tins, 5 kg cartons or 25 kg drums, with the package selected to protect the material during storage and shipment.
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