• Nicotinamide Riboside CAS 1341-23-7
  • Nicotinamide Riboside CAS 1341-23-7
  • Nicotinamide Riboside CAS 1341-23-7

Nicotinamide Riboside CAS 1341-23-7

Nicotinamide Riboside (CAS 1341-23-7) is a pyridine-nucleoside form of Vitamin B3, utilized primarily as a high-value precursor in the industrial synthesis of NAD+ (Nicotinamide Adenine Dinucleotide) boosters and nutritional supplements. This bioactive NR molecule functions as a potent NAD+ metabolic precursor, exhibiting unique pharmacokinetic properties that distinguish it from niacin and niacinamide in nutraceutical formulations. As a critical Nicotinamide ribonucleoside ingredient, it is processed into stable salts for use in anti-aging dietary products and metabolic health formulations. We provide this nutritional raw material with competitive factory pricing to support supplement brand manufacturing and ensure bulk supply availability for commercial encapsulation lines. Our technical team accommodates customized specifications for assay purity and particle consistency, while every shipment is fully documented with MSDS, TDS, COA files to ensure strict food safety and regulatory compliance.

  • CAS: 1341-23-7
  • Synonyms: Nicotinamide ribonucleoside, N-Ribosylnicotinamide
  • Einecs: 811-511-0
  • Molecular Formula: C₁₁H₁₅N₂O₅
  • Grade: Nutraceutical / Pharmaceutical grade, ≥99%
  • Package: 1 kg aluminum foil bag, 25 kg fiber drum, or customized
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Product Description

Nicotinamide Riboside (NR) is a vitamin B3 derivative and efficient NAD⁺ precursor used in anti-aging, energy metabolism and cell-health formulations. It is supplied as a high-purity bulk ingredient for dietary supplements, functional foods, cosmetics and R&D formulations.

📧 Email: info@industrochem.com for latest COA, regulatory support, technical data and bulk pricing.

Physicochemical Properties

ItemTypical Data / Description
Chemical NameNicotinamide Riboside
SynonymsNicotinamide β-riboside; N-Ribosylnicotinamide; Nicotinamide ribose
CAS No.1341-23-7
Molecular FormulaC₁₁H₁₅N₂O₅
Molecular Weight255.25 g/mol
Structural TypePyridine nucleoside, vitamin B3 derivative
AppearanceWhite to off-white, low-melting solid / semi-solid
OdorPractically odorless
Assay (HPLC)≥ 99.0% (typical commercial spec)*
SolubilityFreely soluble in water; practically insoluble in most non-polar organic solvents
pKa (strongest acidic)~11.4 (weakly basic/essentially neutral overall)
logP (predicted)Approx. −2.3 (highly polar, hydrophilic)
HygroscopicityHygroscopic – tends to absorb moisture from air
Stability (solid)Stable when kept dry, cool and protected from light; sensitive to moisture and heat
Stability (solution)Aqueous solutions degrade faster at neutral/alkaline pH; more stable under mildly acidic conditions
Storage RecommendationStore tightly sealed at −20 °C or 2–8 °C, in a dry, dark place; protect from air and moisture

Applications

This product is offered as a bulk ingredient for industrial and R&D use, not as a finished consumer product. Typical B2B application fields include:

  1. Dietary Supplement & Nutraceutical Manufacturing
    • Capsule, tablet, powder and sachet formulations focused on:
      • Cellular energy and metabolism support
      • Healthy aging and vitality concepts
    • Often combined with NMN, CoQ10, resveratrol, vitamins and minerals.
  2. Functional Food & Beverage Ingredients
    • Fortification of shots, ready-to-drink beverages, nutrition bars and meal-replacement powders where an NAD⁺ precursor is required.
  3. Cosmetic & Personal Care Formulations
    • Active ingredient for anti-oxidation and “skin energy” concepts in:
      • Anti-aging serums and creams
      • Repair and recovery masks
        (End-product manufacturers must verify local cosmetic regulations before use.)
  4. Pharmaceutical & Biomedical Research
    • Tool compound in studies on:
      • NAD⁺ metabolism and sirtuin activation
      • Mitochondrial function, neuroprotection and metabolic health

Storage Conditions

For best stability and shelf life:

  • Temperature:
    • Recommended: −20 °C (long-term) or 2–8 °C (short-/mid-term) in a dedicated cool room or refrigerator.
  • Environment:
    • Keep in a tightly closed container, with nitrogen or other inert gas blanketing where possible.
    • Store in a dry, well-ventilated area away from strong oxidants and alkaline materials.
    • Protect from direct light and high humidity to minimize degradation.
  • Shelf Life (typical):
    • 24 months from production date in original unopened packaging under recommended conditions (exact validity according to COA).

Safety Precautions

  • Classification:
    • Not expected to be acutely toxic at normal handling levels; treat as a laboratory/industrial organic chemical.
  • Personal Protection:
    • Avoid dust generation and inhalation.
    • Wear appropriate PPE: lab coat/overall, safety glasses, dust mask or respirator (if dust is generated), and chemical-resistant gloves.
  • Handling:
    • Use in well-ventilated areas or with local exhaust.
    • Avoid contact with eyes, skin and clothing.
    • Do not eat, drink or smoke while handling the product; wash hands thoroughly after operation.
  • First Aid (general principles):
    • Inhalation: Move to fresh air; seek medical attention if irritation or discomfort persists.
    • Skin contact: Wash with soap and plenty of water; remove contaminated clothing.
    • Eye contact: Rinse cautiously with water for several minutes; seek medical advice if irritation continues.
    • Ingestion: Rinse mouth with water; seek medical advice if large quantities are swallowed.
  • Spill & Disposal:
    • Avoid creating dust; sweep up or vacuum into suitable labeled containers for recovery or disposal.
    • Dispose of in accordance with local regulations for organic chemical waste.

FAQ - Technical & Supply Chain

  • Q:

    What characterizes the chemical identity of CAS 1341-23-7 within the Vitamin B3 family?

    A: CAS 1341-23-7 specifically defines the nucleoside form where nicotinamide is linked to a ribose ring, chemically distinct from the simple amide structure of Nicotinamide (Vitamin B3) or the acid form of Niacin.
  • Q:

    Is this material intended for direct tableting or capsule filling?

    A: This product is supplied as a raw chemical ingredient (API/Food Grade Raw Material) intended for industrial formulation into finished dosage forms like capsules or tablets, rather than for direct retail use.
Documents

Documents and Product Support

For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.

  • COA for batch-based quality reference
  • TDS for key physical and chemical information
  • SDS / MSDS for handling, storage, and safety reference
  • Packing information for sample, trial, and bulk orders
  • Technical communication based on application and specification requirements
Quotation

Information to Confirm Before Quotation

Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.

  • Product name and CAS number
  • Application or intended end use
  • Required purity, grade, or specification
  • Sample quantity, trial order, or bulk demand
  • Preferred packing form or net weight
  • Destination country or port
  • Required documents or compliance expectations
Storage & Handling

Packaging, Storage, and Handling Notes

Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.

Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.

Supply Support

Sample, Bulk Order and Repeat Supply Support

Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.

For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.

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