What is Dexpanthenol CAS 81-13-0?

Dexpanthenol is the biologically active D-enantiomer of panthenol, also known as D-panthenol or provitamin B5. It has the molecular formula C9H19NO4 and a molecular weight of about 205.25 g/mol.

What is the difference between Dexpanthenol and DL-Panthenol?

Dexpanthenol is the active D-form, while DL-panthenol is a 50:50 racemic mixture of D- and L-panthenol. The L-form is not efficiently converted to vitamin B5, so the D-form provides the full biological activity and is the preferred specification for functional cosmetic or topical use.

What are the main applications of Dexpanthenol?

It is used in skin care, hair care, and topical formulations for moisturizing, humectant, emollient, and conditioning benefits. It is also used in pharmaceutical-related preparations where panthenol functionality is specified.

What are the typical physical and solubility properties of Dexpanthenol?

Dexpanthenol is usually a colorless to slightly yellowish clear, viscous liquid. It is freely soluble in water and soluble in alcohol and propylene glycol, with a density commonly reported around 1.20 g/mL at 20 deg C.

How should Dexpanthenol be stored and handled?

Store it in tightly closed original containers in a cool, dry, well-ventilated area away from excessive heat and direct sunlight. Keep containers sealed after opening and protect the material from contamination during handling, storage, and transport.

Dexpanthenol CAS 81-13-0

Dexpanthenol CAS 81-13-0 is positioned in industrial supply as a formulation ingredient rather than a general chemical intermediate. In practical use, it is mainly selected for skin care, hair care, and topical pharmaceutical formulations where panthenol-based conditioning and moisturizing performance is required. It is commonly handled as a liquid raw material for formulation use, and routine supply is generally supported with standard packaging and technical documentation for qualification and purchasing review. Niacinamide is a related water-soluble personal-care active to compare where a vitamin B3 derivative is specified instead of panthenol-based conditioning.

CAS: 81-13-0
Synonyms: Dexpanthenol; D-Panthenol; D-Pantothenyl Alcohol; Provitamin B5
Einecs: 201-327-3
Molecular Formula: C9H19NO4
Grade: Supply specification should be selected according to the intended cosmetic or topical formulation standard.
Package: Available in standard export packaging suitable for liquid raw materials.

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Product Description

1 Physicochemical Properties

2 Typical Applications

3 Packaging

4 Storage

Physicochemical Properties

Property	Typical Reference Information
Appearance	Colorless to pale yellow liquid or viscous material, depending on grade and supply form
Molecular Formula	C9H19NO4
Molecular Weight	205.25
Physical Form	Commonly supplied as liquid or formulation-use material
Density	About 1.20 g/mL at 20°C
Water Solubility	Water-soluble
Stability Character	Reported as stable in aqueous solution under suitable handling conditions
Odor	Mild characteristic odor
Supply Note	Typical commercial properties may vary by grade and application direction

Typical Applications

Personal care formulations for skin-conditioning and moisture-support functions.
Hair care products where panthenol-type conditioning support is required.
Topical care and related external-use formulations.
Pharmaceutical-related preparations and quality-controlled formulation systems where dexpanthenol is specified.

Specific end-use suitability should be evaluated according to formulation design, regulatory requirements, and target market standards.

For related personal-care active ingredient pages, review Nicotinamide, Azelaic Acid, and 10-Hydroxydecanoic Acid.

Packaging

Dexpanthenol is usually packed in clean, sealed containers suitable for formulation-use raw materials and export handling. Depending on the supply form and order quantity, packaging may be prepared in drums, lined containers, or other compatible containers used for liquid or viscous materials. The product should be packed in a way that helps maintain cleanliness, reduces contamination risk, and supports stable handling during storage and transport. Packaging arrangement can be matched to order volume and logistics requirements.

Storage

Store in a cool, dry, and well-ventilated place in tightly closed original containers. Protect from excessive heat, direct sunlight, and contamination during storage and transport. Keep the package well sealed after opening and maintain container integrity throughout handling and warehousing.

FAQ - Technical & Supply Chain

Q:
What is Dexpanthenol CAS 81-13-0?

A: Dexpanthenol is the biologically active D-enantiomer of panthenol, also known as D-panthenol or provitamin B5. It has the molecular formula C9H19NO4 and a molecular weight of about 205.25 g/mol.
Q:
What is the difference between Dexpanthenol and DL-Panthenol?

A: Dexpanthenol is the active D-form, while DL-panthenol is a 50:50 racemic mixture of D- and L-panthenol. The L-form is not efficiently converted to vitamin B5, so the D-form provides the full biological activity and is the preferred specification for functional cosmetic or topical use.
Q:
What are the main applications of Dexpanthenol?

A: It is used in skin care, hair care, and topical formulations for moisturizing, humectant, emollient, and conditioning benefits. It is also used in pharmaceutical-related preparations where panthenol functionality is specified.
Q:
What are the typical physical and solubility properties of Dexpanthenol?

A: Dexpanthenol is usually a colorless to slightly yellowish clear, viscous liquid. It is freely soluble in water and soluble in alcohol and propylene glycol, with a density commonly reported around 1.20 g/mL at 20 deg C.
Q:
How should Dexpanthenol be stored and handled?

A: Store it in tightly closed original containers in a cool, dry, well-ventilated area away from excessive heat and direct sunlight. Keep containers sealed after opening and protect the material from contamination during handling, storage, and transport.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

COA, TDS, SDS/MSDS and packing details are available on request.

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Send the CAS number, grade, quantity, packing preference and destination.

Sample & Supply

Support is available for samples, trial orders, bulk and repeat supply.

Storage & Shipping

Product-specific conditions are confirmed before order.

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