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    HomeProductsLife ScienceAPI & IntermediatesAzilsartan CAS 147403-03-0
    • Azilsartan CAS 147403-03-0
    • Azilsartan CAS 147403-03-0

    Azilsartan CAS 147403-03-0

    Azilsartan (CAS 147403-03-0), chemically designated as TAK-536 or Azilsartan free acid, is a benzimidazole-derived angiotensin II receptor antagonist (ARB). Functioning as a high-affinity blocker of the AT1 receptor subtype, this crystalline solid serves as the active pharmaceutical ingredient (API) and key precursor in the synthesis of the prodrug Azilsartan Medoxomil. It is extensively utilized in the industrial production of antihypertensive formulations and cardiovascular research reagents. We provide this industrial material with competitive factory pricing to support continuous manufacturing operations, alongside options for customized specifications. Essential technical documentation, including MSDS, TDS, COA, is readily available for all bulk supply orders.

    • CAS: 147403-03-0
    • Synonyms: TAK-536, Azilsartan free acid, Azilsartan acid, 2-ethoxy-1-[[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid
    • Molecular Formula: C25H24N4O3
    • Grade: Pharmaceutical Grade
    • Package: 25 kg/drum
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    Product Description

    1 Product Introduction
    2 Physicochemical Properties
    3 Applications
    4 Storage Conditions
    5 Safety Precautions

    Product Introduction

    Azilsartan is a potent antihypertensive drug used in the treatment of high blood pressure (hypertension). It belongs to the angiotensin II receptor antagonist class, which works by blocking the effects of a chemical that causes blood vessels to constrict, thereby reducing blood pressure.

    Physicochemical Properties

    PropertyValue
    AppearanceWhite to off-white powder
    Melting Point191-193°C
    SolubilitySoluble in organic solvents (e.g., DMSO, methanol), insoluble in water
    Purity≥ 98%
    Molecular Weight436.5 g/mol

    Applications

    Azilsartan is primarily used for:

    • Treatment of hypertension: Used to lower high blood pressure and improve cardiovascular health.
    • Management of heart failure: Often prescribed in combination with other drugs for heart failure management.

    Storage Conditions

    • Storage Temperature: Store in a cool, dry place at a temperature between 15–30°C.
    • Shelf Life: Typically 2 years when stored under recommended conditions.
    • Packaging: Ensure the packaging is sealed to avoid exposure to moisture and direct sunlight.

    Safety Precautions

    • Handling: Handle with care and avoid inhalation or skin contact.
    • Personal Protection: Wear appropriate PPE, including gloves, goggles, and lab coat.
    • Disposal: Dispose of any waste material in accordance with local environmental regulations.

    FAQ - Technical & Supply Chain

    • Q:

      Is TAK-536 the technical synonym for Azilsartan CAS 147403-03-0?

      A: Yes, TAK-536 is the development code and common technical synonym for Azilsartan (CAS 147403-03-0), referring to the free acid form of the molecule.
    • Q:

      Is this grade intended for the synthesis of Azilsartan Medoxomil?

      A: Yes, this material is typically applied as the core active intermediate in the esterification process to produce the prodrug Azilsartan Medoxomil for final dosage forms.
    Documents

    Documents and Product Support

    For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.

    • COA for batch-based quality reference
    • TDS for key physical and chemical information
    • SDS / MSDS for handling, storage, and safety reference
    • Packing information for sample, trial, and bulk orders
    • Technical communication based on application and specification requirements
    Quotation

    Information to Confirm Before Quotation

    Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.

    • Product name and CAS number
    • Application or intended end use
    • Required purity, grade, or specification
    • Sample quantity, trial order, or bulk demand
    • Preferred packing form or net weight
    • Destination country or port
    • Required documents or compliance expectations
    Storage & Handling

    Packaging, Storage, and Handling Notes

    Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.

    Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.

    Supply Support

    Sample, Bulk Order and Repeat Supply Support

    Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.

    For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.

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    Product Categories

    Tags:

    Antihypertensive Intermediate Aromatic Acid Derivative Pharmaceutical Ingredient Tetrazole Compound

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