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    HomeProductsLife SciencePharmaceuticalAmifostine CAS 20537-88-6
    • Amifostine CAS 20537-88-6
    • Amifostine CAS 20537-88-6

    Amifostine CAS 20537-88-6

    Amifostine is a small-molecule organophosphorothioate compound used as a pharmaceutical chemical intermediate, also commonly referred to as WR-2721 or its dephosphorylated form WR-1065, all corresponding to the same substance identity under CAS 20537-88-6. It functions through enzymatic dephosphorylation to generate active thiol species, which are involved in cellular protection mechanisms against radiation-induced damage, making it typically applied in radioprotective pharmaceutical synthesis and related medicinal production processes. For industrial users, the material is available with competitive factory pricing, customized specifications, and full documentation including MSDS, TDS, COA, supporting bulk supply requirements.

    • CAS: 20537-88-6
    • Synonyms: Amifostine, WR-2721, Ethyol, S-2-(3-aminopropylamino)ethyl phosphorothioate
    • Molecular Formula: C5H15N2O3PS
    • Grade: Industrial grade 98%
    • Package: 200kg iron drum or 50kg plastic drum packaging
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    Product Description

    amifostine

    alias: 2-(3-aminopropylamino)ethylsulfanylphosphonic acid; Ethiofos; Sapep; Gammaphos; Apaetp;

    CAS Number: 20537-88-6Molecular formula: C5H15N2O3PS

    Molecular weight: 214.22300

    Appearance and properties: white crystalline powder or lyophilized lumps; There is a special smellDensity: 1.367 g/cm3

    Melting point: 160-161ºC

    Boiling point: 441.7ºC at 760 mmHg

    Flash point: 220.9ºC

    Storage conditions: The warehouse is ventilated and dried at low temperature

    Category: Chemical drugs and biological products >> Drugs for the treatment of tumors >> Anti-tumor adjuvant drugs

    Specification: 200g/piece, or 1kg/bag

    Uses: Amphostine is a normal cell protector and is mainly used in the adjuvant treatment of various cancers in clinical practice.

    FAQ - Technical & Supply Chain

    • Q:

      Does CAS 20537-88-6 refer to the phosphorylated thiophosphonate prodrug used as a cytoprotective agent?

      A: Yes. CAS 20537-88-6 identifies Amifostine (ethiofos), an organic thiophosphate compound. It is technically characterized as a prodrug that requires dephosphorylation by alkaline phosphatase into its active thiol metabolite, WR-1065, to provide specialized protective effects against certain therapeutic side effects in industrial and pharmaceutical synthesis contexts.
    • Q:

      Is Amifostine intended for industrial pharmaceutical production rather than laboratory research only?

      A: Amifostine is typically supplied as a chemical intermediate intended for pharmaceutical manufacturing and process use, rather than being limited to small-scale laboratory research applications.
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    Organophosphorus Compound Pharmaceutical Ingredient Thiophosphate Compound

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