Alpha Lipoic Acid CAS 1077-28-7

Alpha Lipoic Acid (ALA) is a sulfur-containing antioxidant widely used in nutritional supplements, pharmaceuticals, and cosmetic formulations. It can function in both water- and fat-soluble environments, helping to scavenge free radicals and support energy metabolism.

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Physicochemical Properties

Applications

1. Dietary Supplements & Nutraceuticals
   • Used in capsules, tablets, and softgels as an antioxidant ingredient.
   • Often combined with vitamins (e.g., B-group, vitamin C, vitamin E) for metabolic and immune support.
   • Applied in formulations marketed for blood sugar management support, neuropathy support, and general wellness.
2. Pharmaceutical & Clinical Nutrition
   • Active ingredient or functional excipient in prescription or hospital nutrition products in some markets.
   • Investigated for its role in managing diabetic complications, liver function support, and neuroprotective applications (depending on local regulations).
3. Cosmetics & Personal Care
   • Incorporated into anti-aging creams, serums, and dermal products as an antioxidant to help protect skin from oxidative stress.
   • Can be used in combination with other actives (e.g., CoQ10, vitamin C, niacinamide) for premium skincare lines.
4. Functional Foods & Beverages (where permitted)
   • Added to fortified foods, drinks, or powder blends as a value-added antioxidant ingredient, subject to local food regulations.

Note: Actual application and dosage should follow local laws and regulations in the destination country.

Storage Conditions

• Store in a cool, dry, and well-ventilated warehouse.
• Recommended storage temperature: 2–8 °C for best stability.
• Keep container tightly closed, protected from moisture and direct sunlight.
• Avoid exposure to strong oxidizing agents and high temperatures.
• Use opened containers as soon as possible and reseal carefully after each use.

Safety Precautions

Based on safety data sheets and regulatory classifications, Alpha Lipoic Acid is generally considered of low acute toxicity, but industrial handling still requires standard chemical safety measures.

• Hazard Statements (typical EU/GHS classification):
  • Harmful if swallowed.
  • May cause irritation to eyes, skin, and respiratory tract at high dust levels.
• Personal Protective Equipment (PPE):
  • Wear appropriate protective gloves, lab coat/overall, and safety glasses when handling bulk powder.
  • Use dust mask or suitable respirator if dust formation is likely.
• Handling Advice:
  • Avoid breathing dust; use local exhaust ventilation in production areas.
  • Avoid contact with eyes, skin, and clothing.
  • Do not eat, drink, or smoke when using this material; wash hands thoroughly after handling.
• First-Aid Measures:
  • Inhalation: Move person to fresh air; seek medical attention if discomfort persists.
  • Skin contact: Wash with soap and plenty of water; remove contaminated clothing.
  • Eye contact: Rinse cautiously with water for several minutes; seek medical attention if irritation continues.
  • Ingestion: Rinse mouth; do not induce vomiting; seek medical advice immediately.
• Spill & Disposal:
  • Avoid creating dust; sweep up and place into suitable labelled containers for recovery or disposal.
  • Dispose of in accordance with local, regional, and national regulations.