What is Nicotinamide Vitamin B3 CAS 98-92-0?

Nicotinamide, also called niacinamide or pyridine-3-carboxamide, is the amide form of vitamin B3. It is a white crystalline powder used in cosmetics, dietary supplements, food fortification and feed premixes.

How is nicotinamide different from niacin?

Niacin, or nicotinic acid, has a carboxylic acid group, while nicotinamide has an amide group. This difference makes nicotinamide better tolerated in cosmetics because it avoids the skin-flushing effect commonly associated with niacin.

What is it used for in skin care?

It is used in serums, creams, lotions and toners to support the skin barrier, improve the appearance of uneven tone, reduce visible redness and help balance the appearance of sebum.

What specifications should be checked before ordering?

Confirm HPLC assay, appearance, melting range, pH of a dilute aqueous solution, loss on drying, residue on ignition, related substances, heavy metals and microbial limits. Specify cosmetic, food, feed or pharmaceutical grade as appropriate.

How should Nicotinamide be stored and handled?

Store in tightly closed, light-protected containers in a cool, dry place, away from strong oxidizers and excessive heat. Use powder-handling controls and suitable PPE, and follow the supplier's safety instructions.

Nicotinamide (Vitamin B3) CAS 98-92-0

Nicotinamide (CAS 98-92-0), chemically identified as pyridine-3-carboxamide, is the biologically active amide form of Vitamin B3 functioning as a versatile skin conditioning agent and essential nutrient in cosmetic skin care formulation and animal nutrition. This white crystalline powder, widely technically recognized as Niacinamide or Vitamin PP, serves as a potent cell-communicating ingredient to improve skin barrier function and reduce hyperpigmentation without the vasodilation (flushing) side effect associated with Nicotinic Acid. We provide bulk supply of this USP/Cosmetic grade ingredient with competitive factory pricing to empower personal care brands and feed millers. Our production ensures low nicotinic acid residue, making MSDS, TDS, COA available alongside customized specifications to meet high-purity whitening or feed premix standards.

CAS: 98-92-0
Synonyms: Niacinamide, Vitamin PP, Pyridine-3-carboxamide, 3-Pyridinecarboxamide, Nicotinic acid amide
Einecs: 202-713-4
Molecular Formula: C6H6N2O
Grade: Cosmetic Grade
Package: 25 kg fiber drum / carton with inner PE bags or as customer’s request

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Product Description

Vitamin B3 (Niacinamide) is a water-soluble vitamin widely used in food, feed, pharmaceuticals and personal care. It plays an essential role in energy metabolism and skin barrier repair. Our Vitamin B3 is produced under strict quality management systems, offering stable quality, low impurities and excellent flowability to meet the requirements of tablet pressing, capsule filling, premix blending and cosmetic formulations.

1 Physicochemical Properties

2 Applications

3 Storage Conditions

4 Safety Precautions

Physicochemical Properties

Item	Specification / Description
Chemical Name	Niacinamide (Nicotinamide)
CAS	98-92-0
Einecs	202-713-4
Molecular Formula	C₆H₆N₂O
Molecular Weight	122.12 g/mol
Appearance	White or almost white crystalline powder
Assay (HPLC)	≥ 99.0%
Melting Point	128 – 131 °C
Odor	Practically odorless
Solubility in Water	Freely soluble
Solubility in Ethanol	Soluble
pH (5% aqueous solution)	6.0 – 7.5
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Appearance of Solution	Clear, colorless to slightly yellow
Bulk Density	Approx. 0.4 – 0.7 g/mL
Grade	Food / Pharma / Cosmetic Grade
Standard Package	25 kg fiber drum / carton with inner PE liner
Shelf Life	24 months in original unopened package

(Typical factory specifications; can be adjusted according to customer’s specific requirement.)

Applications

Food & Beverage Industry
- Used as a nutritional fortifier in flour, cereals, dairy products, beverages and health foods.
- Helps maintain normal metabolism of carbohydrates, fats and proteins.
Feed Industry
- Applied in premixes and complete feeds for poultry, swine, ruminants and aquaculture.
- Supports growth performance, feed conversion and animal health.
Pharmaceuticals & Nutraceuticals
- Used in tablets, capsules and oral liquid formulations as Vitamin B complex component.
- Suitable for OTC and dietary supplement products targeting energy, nerve and skin health.
Cosmetics & Personal Care
- Widely used in skin-care formulations such as creams, lotions, serums and masks.
- Helps improve skin barrier function, even skin tone and reduce the appearance of fine lines.
- Compatible with most emulsions and water-based systems.
Other Uses
- Intermediate in certain chemical and biochemical syntheses.
- Used in functional formulations requiring stable, water-soluble vitamin additives.

Storage Conditions

Store in a cool, dry and well-ventilated warehouse.
Keep away from heat sources, moisture and direct sunlight.
Keep the package tightly closed after opening to avoid caking and contamination.
Recommended storage temperature: below 25 °C and relative humidity < 65%.
Use on a first-in, first-out (FIFO) basis and avoid long-term open storage.

Safety Precautions

Vitamin B3 (Niacinamide) is generally considered safe in normal industrial use and approved limits, but:
- Avoid creating dust clouds; use local exhaust ventilation where necessary.
- Operators should wear appropriate PPE: dust mask, safety glasses and gloves.
Inhalation: Move to fresh air, rinse mouth with water if necessary. Seek medical advice if discomfort persists.
Skin Contact: Wash with soap and water. Remove contaminated clothing.
Eye Contact: Rinse immediately with plenty of water for several minutes. Seek medical attention if irritation continues.
Ingestion: Rinse mouth with water. Do not induce vomiting. Get medical attention if large quantities are swallowed.
Follow local regulations for waste disposal and spill clean-up (collect spilled material, avoid discharge into drains).

FAQ - Technical & Supply Chain

Q:
What is Nicotinamide Vitamin B3 CAS 98-92-0?

A: Nicotinamide, also called niacinamide or pyridine-3-carboxamide, is the amide form of vitamin B3. It is a white crystalline powder used in cosmetics, dietary supplements, food fortification and feed premixes.
Q:
How is nicotinamide different from niacin?

A: Niacin, or nicotinic acid, has a carboxylic acid group, while nicotinamide has an amide group. This difference makes nicotinamide better tolerated in cosmetics because it avoids the skin-flushing effect commonly associated with niacin.
Q:
What is it used for in skin care?

A: It is used in serums, creams, lotions and toners to support the skin barrier, improve the appearance of uneven tone, reduce visible redness and help balance the appearance of sebum.
Q:
What specifications should be checked before ordering?

A: Confirm HPLC assay, appearance, melting range, pH of a dilute aqueous solution, loss on drying, residue on ignition, related substances, heavy metals and microbial limits. Specify cosmetic, food, feed or pharmaceutical grade as appropriate.
Q:
How should Nicotinamide be stored and handled?

A: Store in tightly closed, light-protected containers in a cool, dry place, away from strong oxidizers and excessive heat. Use powder-handling controls and suitable PPE, and follow the supplier's safety instructions.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

COA, TDS, SDS/MSDS and packing details are available on request.

Quotation

Send the CAS number, grade, quantity, packing preference and destination.

Sample & Supply

Support is available for samples, trial orders, bulk and repeat supply.

Storage & Shipping

Product-specific conditions are confirmed before order.

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