Is Niacinamide the same purchasing item as niacin or nicotinic acid?

No. Niacinamide is nicotinamide, CAS 98-92-0. Niacin, also called nicotinic acid, is a different chemical substance with CAS 59-67-6. The names are related through vitamin B3 terminology but cannot be used interchangeably in specifications, COAs, labels or change-control records.

Does a Niacinamide grade for one application automatically meet another application standard?

No. Cosmetic, food, supplement and pharmacopeial applications can require different specifications, documentation and acceptance limits. The application, target market and required standard must be identified before qualification. A high assay result alone does not demonstrate that the offered material meets every applicable identity, impurity or documentary requirement.

Which points should be controlled when changing an established Niacinamide source?

Compare identity, assay, related substances, water or loss on drying, residue, colour and particle-size requirements where relevant, using the agreed methods. Then verify behaviour in the intended formulation or process. Change approval should be based on the specified acceptance criteria and the required supporting documents, not solely on CAS 98-92-0.

Niacinamide (Nicotinamide) CAS 98-92-0

Niacinamide (nicotinamide) (CAS 98-92-0, EC 202-713-4) is supplied as a raw material for formulation manufacturers and ingredient distributors. Share your intended application and required standard for a quotation matched to the appropriate specification. COA, TDS and SDS are available for the supplied grade.

CAS: 98-92-0
Synonyms: Niacinamide; Nicotinamide; Pyridine-3-carboxamide; Nicotinic Acid Amide; Vitamin B3 Amide
Einecs: 202-713-4
Molecular Formula: C6H6N2O
Grade: Niacinamide grade selected for the intended use and agreed quality standard
Package: Niacinamide packaging specified in our quotation for the required quantity and destination

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Product Description

1 Product Overview

2 Use in cosmetic formulations

3 Product Information / Specifications

4 Niacinamide Assay and Impurity Control

5 Storage, Safety and Documentation

Product Overview

Niacinamide (nicotinamide, CAS 98-92-0) is pyridine-3-carboxamide, the amide form of vitamin B3. It is used in cosmetic, food, supplement and pharmaceutical formulations, with grade selection based on the intended application and applicable standard. Key selection criteria include assay, identification, related substances, water or loss on drying, and particle size where relevant. Niacinamide is distinct from niacin or nicotinic acid (CAS 59-67-6).

Use in cosmetic formulations

Niacinamide is water-soluble and is used in cosmetic formulations designed to support the skin barrier and improve the appearance of uneven skin tone. It can be incorporated into the aqueous phase of creams, lotions, gels and other suitable topical systems. Evaluate the offered grade in the complete formula for dissolution, pH, processing compatibility and stability during storage. Include residual nicotinic acid in the relevant related-substance review. A high assay result alone does not establish finished-product efficacy.

For water-based niacinamide serums and the aqueous phase of emulsions, Glycerol (Glycerin) and Sodium Hyaluronate are relevant moisturising co-ingredients. They complement niacinamide in the formulation rather than replace it. Select each material for the intended texture and verify dissolution, pH, viscosity and stability in the finished formula.

In niacinamide creams and lotions, Caprylic/Capric Triglyceride (GTCC) can be considered as an oil-phase emollient. It does not replace the aqueous phase used to dissolve niacinamide. Assess the complete emulsifier system and processing conditions; use in commercial formulations does not establish that every grade or ratio is interchangeable.

Product Information / Specifications

Product	Niacinamide (Nicotinamide) CAS 98-92-0
CAS No.	98-92-0
EC No.	202-713-4
Molecular Formula / Identity	C6H6N2O
Molecular Weight	122.12 g/mol
Appearance	Typically a white crystalline powder; appearance and solution clarity are assessed against the selected niacinamide specification.
Synonyms	Niacinamide, Nicotinamide, Pyridine-3-carboxamide, Vitamin B3 amide
Grade / Supply Specification	Niacinamide grade selected for the intended use and agreed quality standard
Packaging	Niacinamide packaging specified in our quotation for the required quantity and destination

Niacinamide Assay and Impurity Control

Assess niacinamide identity and assay using the method required by the selected grade or standard. HPLC can quantify niacinamide and evaluate specified related substances, including nicotinic acid, when the method is suitable for those analytes and limits. A chromatographic area percentage is not automatically equivalent to an assay result on the agreed mass or dried-substance basis. Compare impurity limits separately from the main assay, and specify water or loss on drying, residue and particle-size requirements where relevant. We can provide HPLC chromatograms and method information for niacinamide quality evaluation.

Storage, Safety and Documentation

The TDS and SDS we provide describe storage and handling for the niacinamide grade supplied. Follow these product-specific instructions during storage and use. We can provide the COA to support your quality review. Include any destination-market documentation requirements with your enquiry.

FAQ - Technical & Supply Chain

Q:
Is Niacinamide the same purchasing item as niacin or nicotinic acid?

A: No. Niacinamide is nicotinamide, CAS 98-92-0. Niacin, also called nicotinic acid, is a different chemical substance with CAS 59-67-6. The names are related through vitamin B3 terminology but cannot be used interchangeably in specifications, COAs, labels or change-control records.
Q:
Does a Niacinamide grade for one application automatically meet another application standard?

A: No. Cosmetic, food, supplement and pharmacopeial applications can require different specifications, documentation and acceptance limits. The application, target market and required standard must be identified before qualification. A high assay result alone does not demonstrate that the offered material meets every applicable identity, impurity or documentary requirement.
Q:
Which points should be controlled when changing an established Niacinamide source?

A: Compare identity, assay, related substances, water or loss on drying, residue, colour and particle-size requirements where relevant, using the agreed methods. Then verify behaviour in the intended formulation or process. Change approval should be based on the specified acceptance criteria and the required supporting documents, not solely on CAS 98-92-0.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

Tell us which documents your procurement team needs. Before an order, we will check whether the quoted source can provide them for the offered lot.

Quotation

Send the CAS number, grade, quantity, packing preference and destination.

Sample & Supply

Ask whether samples, trial quantities or repeat orders are possible. We will check each request against the sourced product and current offer.

Storage & Shipping

Product-specific conditions are confirmed before order.

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