Are Tosyl Chloride and p-Toluenesulfonyl Chloride the same substance?

Yes. Tosyl Chloride, TsCl, p-Toluenesulfonyl Chloride and 4-methylbenzenesulfonyl chloride refer to CAS 98-59-9. Confirm the para isomer because ortho-toluenesulfonyl chloride and other positional isomers are different substances and may affect downstream impurity control.

Which quality parameters should be specified for bulk Tosyl Chloride?

Typical controls include assay by an agreed method, ortho-isomer and other isomers, p-toluenesulfonic acid or free acidity, water, color, melting range and particle form. Compare the batch COA against the same methods because moisture hydrolysis can reduce usable sulfonyl chloride content.

What packaging and storage controls are needed for Tosyl Chloride?

Use tightly closed, moisture-resistant packaging with the agreed liner, net weight and package size. Confirm production or retest date, storage temperature and transport classification; protect the material from water, humid air and excessive heat according to the current SDS.

Tosyl Chloride (TsCl) CAS 98-59-9

Tosyl Chloride (TsCl) , CAS 98-59-9 and EC 202-684-8 , is 4-methylbenzenesulfonyl chloride with formula C7H7ClO2S and molecular weight 190.65 g/mol. It is a moisture-sensitive sulfonylating reagent. Buyers should define assay, para-isomer content, ortho-toluenesulfonyl chloride and other isomers, p-toluenesulfonic acid or hydrolysis products, water, free acidity, color and particle-size requirements.

CAS: 98-59-9
Synonyms: Tosyl chloride, TsCl, p-Toluenesulfonyl chloride, 4-Methylbenzenesulfonyl chloride
Einecs: 202-684-8
Molecular Formula: C₇H₇ClO₂S
Grade: Confirm identity, assay method, water or residual solvents, product-specific impurities and physical form against the current COA; no end-use grade is assumed.
Package: State required quantity and destination; confirm the current container, light or moisture protection, net weight, storage conditions and transport requirements against the current COA and SDS.

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Product Description

1 Identity and specification

2 Quality controls for purchasing

3 Applications and grade selection

4 Storage and handling

5 Documentation and quotation details

Identity and specification

Item	Verified purchasing information
Product	Tosyl Chloride; p-toluenesulfonyl chloride; TsCl
CAS / EC	98-59-9 / 202-684-8
Formula / molecular weight	C7H7ClO2S / 190.65 g/mol
Critical selection point	Para-isomer purity and hydrolysis control

Tosyl Chloride is the para-methylbenzenesulfonyl chloride isomer. It should be distinguished from ortho- and meta-toluenesulfonyl chlorides. Water exposure converts reactive sulfonyl chloride into acid-related hydrolysis products.

Quality controls for purchasing

Specify assay and para-isomer content with limits for ortho, meta and other positional isomers.
Control p-toluenesulfonic acid, water, free acidity and other hydrolysis or process impurities.
Define color, melting behavior and particle size when charging, filtration or reaction rate is important.

Applications and grade selection

TsCl is used to convert alcohols, phenols and amines into tosylates or sulfonamides under controlled conditions. Reaction performance depends on assay, hydrolysis state, base, solvent, temperature and substrate. A sample trial should precede supplier substitution.

Storage and handling

Keep tightly closed in a dry moisture-barrier package, away from water, bases and incompatible oxidizers. Use dry sampling and transfer procedures and follow the SDS for corrosive dust, decomposition products and spill response.

Documentation and quotation details

State assay, isomer and acid limits, water, particle requirements, quantity, package, destination and schedule. Request a lot COA, SDS, TDS and any transport or origin documentation needed by the receiving site.

FAQ - Technical & Supply Chain

Q:
Are Tosyl Chloride and p-Toluenesulfonyl Chloride the same substance?

A: Yes. Tosyl Chloride, TsCl, p-Toluenesulfonyl Chloride and 4-methylbenzenesulfonyl chloride refer to CAS 98-59-9. Confirm the para isomer because ortho-toluenesulfonyl chloride and other positional isomers are different substances and may affect downstream impurity control.
Q:
Which quality parameters should be specified for bulk Tosyl Chloride?

A: Typical controls include assay by an agreed method, ortho-isomer and other isomers, p-toluenesulfonic acid or free acidity, water, color, melting range and particle form. Compare the batch COA against the same methods because moisture hydrolysis can reduce usable sulfonyl chloride content.
Q:
What packaging and storage controls are needed for Tosyl Chloride?

A: Use tightly closed, moisture-resistant packaging with the agreed liner, net weight and package size. Confirm production or retest date, storage temperature and transport classification; protect the material from water, humid air and excessive heat according to the current SDS.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

Documents

COA, TDS, SDS/MSDS and packing details are available on request.

Quotation

Send the CAS number, grade, quantity, packing preference and destination.

Sample & Supply

Support is available for samples, trial orders, bulk and repeat supply.

Storage & Shipping

Product-specific conditions are confirmed before order.

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