Malonic acid, CAS 141-82-2, also called propanedioic acid, is a white crystalline dicarboxylic acid used in fine-chemical synthesis and specialty materials. Its active methylene group supports carbon–carbon bond formation, while its two carboxyl groups enable ester and derivative chemistry.
Malonic Acid CAS 141-82-2
- CAS: 141-82-2
- Synonyms: Malonic acid; Propanedioic acid; Methanedicarboxylic acid
- Einecs: 205-503-0
- Molecular Formula: C₃H₄O₄
- Grade: For industrial synthesis; assay and impurity limits by specification
- Package: Sealed fibre drums; pack size stated in the quotation
Product Description
Malonic acid in synthesis
Malonic acid is the free acid. Malonate salts and esters are different starting materials with different compositions and reaction behaviour. For selected aromatic β-amino-acid routes, 4-chlorobenzaldehyde and ammonium acetate are complementary reactants used with malonic acid; the reagent set depends on the target intermediate.
For ester and resin development, glutaric acid and adipic acid provide longer-chain dicarboxylic-acid comparisons. Their five- and six-carbon structures differ from the three-carbon structure of malonic acid. The acids have different thermal and reaction behaviour and are not direct replacements in an established process.
Assay and impurity control
Neutralization titration is a common assay method for malonic acid. It measures acid equivalents and does not by itself distinguish every acidic impurity. Relevant quality checks include appearance, assay, loss on drying or water content by the stated method, residue on ignition, and process-specific chloride, sulfate or metal limits. Loss on drying is not automatically equivalent to a water-content result.
Where organic-acid impurities matter, a suitable HPLC method can separate malonic acid from specified components. The method, calibration and reporting basis should match the analytical requirement; chromatographic area percentage is not automatically a mass-purity value.
Documents and analytical support
We can provide a Certificate of Analysis (COA), Technical Data Sheet (TDS) and Safety Data Sheet (SDS) for the agreed malonic acid specification. Chromatograms and analytical information can also be provided for the applicable impurity test.
Packaging and quotations
The crystalline solid can be supplied in sealed fibre drums, with pack size and packing arrangement stated in the quotation. Send the required assay, key impurity limits, quantity and delivery destination. The intended synthesis and preferred pack size help define a suitable offer.
FAQ - Technical & Supply Chain
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Q:
Are malonic acid and propanedioic acid the same material?
A: Yes. Malonic acid, propanedioic acid and methanedicarboxylic acid identify CAS 141-82-2, with formula C3H4O4. Malic acid, maleic acid and malonate salts or esters are different chemicals. -
Q:
Does a titration assay describe the complete impurity profile?
A: No. Neutralization titration measures acid equivalents. Other titratable acidic components can affect the result, so the assay should be considered together with the specified impurity tests and their reporting basis. -
Q:
Can HPLC data support malonic acid quality evaluation?
A: Yes. Suitable liquid-chromatography methods can separate malonic acid and relevant organic-acid impurities. We can provide applicable chromatograms and test information. Quantitative results require appropriate calibration; peak-area percentage alone is not a universal mass-purity measure. -
Q:
How is crystalline malonic acid packaged and stored?
A: Sealed fibre drums are a suitable industrial packaging option. Keep the container tightly closed and protect the material from moisture and excessive heat. Follow the storage conditions and handling instructions in the TDS and SDS for the supplied grade. -
Q:
What information is useful for a malonic acid quotation?
A: Send the required assay, critical impurity limits, quantity and delivery destination. If known, include the intended reaction and preferred pack size. For pharmaceutical synthesis, include any additional impurity or quality requirements.
Ordering & Documentation
Key information for document requests, quotations, and supply planning.
Documents
Tell us which documents your procurement team needs. Before an order, we will check whether the quoted source can provide them for the offered lot.
Quotation
Send the CAS number, grade, quantity, packing preference and destination.
Sample & Supply
Ask whether samples, trial quantities or repeat orders are possible. We will check each request against the sourced product and current offer.
Storage & Shipping
Product-specific conditions are confirmed before order.
