• Emulsifier BY-160 / Cremophor EL CAS 61791-12-6
  • Emulsifier BY-160 / Cremophor EL CAS 61791-12-6
  • Emulsifier BY-160 / Cremophor EL CAS 61791-12-6

Emulsifier BY-160 / Cremophor EL CAS 61791-12-6

Emulsifier BY-160 (also known as Cremophor EL, CAS 61791-12-6) is a polyoxyl castor oil nonionic surfactant derived from castor oil ethoxylated with ethylene oxide. It offers excellent emulsifying, solubilizing, and wetting properties in both aqueous and oil-based systems. This product is widely used as an emulsifier and solubilizer in pharmaceutical, cosmetic, and industrial formulations requiring stable O/W emulsions. The product is supplied for industrial use with standard documentation including MSDS, TDS, and COA.

  • CAS: 61791-12-6
  • Synonyms: BY-160, Cremophor EL, Castor Oil Ethoxylate, Polyoxyl castor oil, Polyoxyethylene castor oil, PEG castor oil, Emulsifier BY-160
  • Einecs: 500-147-5
  • Molecular Formula: C57H104O9(CH2CH2O)n
  • Grade: 99%
  • Package: 200kg iron drum or 50kg plastic drum packaging
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Product Description

Physicochemical properties

PropertyValue
Molecular WeightNot precisely defined (varies with degree of ethoxylation)
AppearanceViscous liquid or waxy solid (depending on the degree of ethoxylation)
ColorClear yellow to light yellow
Density1.05 g/mL at 20 °C
Boiling Point232.6 °C (at 101325 Pa) or 305.7 ± 32.0 °C at 760 mmHg (values may vary depending on the source)
Flash Point257 °C
Melting Point4 °C (or not precisely defined, varies with the degree of ethoxylation)
pH5.0-7.0 (1g/10 mL in H₂O) or pH range 6.0-8.0 (values may vary depending on the source)
SolubilitySlightly soluble in chloroform, ethyl acetate, methanol; insoluble in water at room temperature (but solubility increases with temperature, though it decreases again at higher temperatures); soluble in many organic solvents
StabilityStable under normal conditions; incompatible with strong oxidizing agents
Viscosity600-750 mPa·s (25 °C) (value may vary depending on the source)
Water Solubility24.11 mg/L at 25 °C
LogP4.297 at 25 °C

Application Areas

In the field of pesticides, it is used as a monomer for pesticide emulsifiers to improve the dispersibility of drug solutions.
Textile industry: As a synthetic oil agent and wool oil, it enhances fiber processing performance.
Oilfield chemistry: used for crude oil dehydration treatment.
Other fields: emulsification of oil wax, oleic acid, and mineral oil, as well as antistatic spinning oil for vinylon.

Storage conditions

Environmental requirements: It should be stored in a cool, dry, well ventilated place, away from direct sunlight and high temperature environment. The recommended storage temperature should be controlled between 5 ℃ and 35 ℃. Extreme temperatures may cause a decrease in emulsification performance or a change in physical state (such as an increase in viscosity or crystallization)
Sealing: The container must be strictly sealed to prevent air, moisture, or impurities from entering, and to avoid product oxidation or moisture absorption and agglomeration
Avoid light and moisture: Keep away from damp environments. Some products are sensitive to light and long-term exposure may cause damage to their molecular structure

Safety precautions

Packaging specifications: commonly packaged in 200kg iron drums or 50kg plastic drums, ensuring that the container is corrosion-resistant and undamaged
Shelf life: usually 2 years, subject to the manufacturer’s labeling. Performance needs to be retested after the expiration date

FAQ - Technical & Supply Chain

  • Q:

    What is Emulsifier BY-160 / Cremophor EL used for?

    A: Emulsifier BY-160 (Cremophor EL) is a polyoxyl castor oil nonionic surfactant used as an emulsifier and solubilizer in pharmaceutical, cosmetic, and industrial formulations. It is particularly effective for stabilizing O/W emulsions and solubilizing hydrophobic active ingredients.
  • Q:

    Are BY-160 and Cremophor EL the same product?

    A: Yes. BY-160 is the product code commonly used in Asian markets, while Cremophor EL is the brand name recognized internationally. Both refer to the same polyoxyl castor oil ethoxylate with CAS 61791-12-6.
  • Q:

    What industries use Emulsifier BY-160?

    A: BY-160 is used in pharmaceutical formulations (as a solubilizer for poorly soluble drugs), cosmetic and personal care products (creams, lotions), and industrial applications including textile auxiliaries, metalworking fluids, and agrochemical formulations.
  • Q:

    What is the HLB value of Cremophor EL?

    A: Cremophor EL / BY-160 typically has an HLB value of 12–14, making it suitable as an O/W emulsifier and solubilizer. Its hydrophilic-lipophilic balance allows it to effectively stabilize oil-in-water emulsions and improve the bioavailability of hydrophobic compounds.
  • Q:

    Can BY-160 be used in pharmaceutical applications?

    A: Yes, polyoxyl castor oil (Cremophor EL) is a well-established excipient in pharmaceutical formulations, particularly for solubilizing poorly water-soluble drugs in oral and parenteral preparations. Buyers should verify the specific grade and documentation requirements for their intended application.
  • Q:

    What quality indicators should buyers verify when sourcing BY-160?

    A: Key quality indicators include acid value, saponification value, hydroxyl value, water content, and appearance. These parameters ensure consistent emulsification performance and suitability for the target formulation system.
Documents

Documents and Product Support

For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.

  • COA for batch-based quality reference
  • TDS for key physical and chemical information
  • SDS / MSDS for handling, storage, and safety reference
  • Packing information for sample, trial, and bulk orders
  • Technical communication based on application and specification requirements
Quotation

Information to Confirm Before Quotation

Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.

  • Product name and CAS number
  • Application or intended end use
  • Required purity, grade, or specification
  • Sample quantity, trial order, or bulk demand
  • Preferred packing form or net weight
  • Destination country or port
  • Required documents or compliance expectations
Storage & Handling

Packaging, Storage, and Handling Notes

Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.

Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.

Supply Support

Sample, Bulk Order and Repeat Supply Support

Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.

For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.

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