Do DL-Homocysteine Thiolactone Hydrochloride and Homocysteine thiolactone HCl refer to the same substance?

Yes. These names describe the same hydrochloride salt form and correspond to a single CAS number, indicating identical substance identity.

Is DL-Homocysteine Thiolactone Hydrochloride used as an industrial intermediate rather than a finished pharmaceutical product?

It is typically intended for use as an intermediate in pharmaceutical and biochemical synthesis processes, rather than as a finished dosage form.

DL-Homocysteine Thiolactone Hydrochloride CAS 6027-13-0

DL-Homocysteine Thiolactone Hydrochloride is a cyclic thioester amino acid derivative used as a pharmaceutical intermediate, primarily involved in controlled ring-opening and derivatization reactions during synthetic and biochemical process development. As the hydrochloride salt form of homocysteine thiolactone (CAS 6027-13-0), it provides defined reactivity and handling characteristics for downstream transformation in amino acid modification and sulfur-containing compound synthesis. Industrial supply is available with competitive factory pricing, support for customized specifications, and complete documentation including MSDS, TDS, COA, enabling bulk supply for regulated manufacturing environments.

CAS: 6027-13-0
Synonyms: DL-Homocysteine thiolactone HCl, Homocysteine thiolactone hydrochloride, DL-Homocysteine thiolactone salt
Einecs: 227-923-3
Molecular Formula: C₄H₈ClNOS
Grade: Industrial grade 99%
Package: 200kg iron drum or 50kg plastic drum packaging

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Product Description

1 Physicochemical properties

2 Application Areas

3 Storage conditions

4 Safety precautions

Physicochemical properties

Property	Value
Chemical Formula	C₄H₈ClNOS
Molecular Weight	153.63 g/mol
CAS Number	6027-13-0
EINECS Number	227-923-3
Appearance	White crystalline powder
Melting Point	202 °C (dec.) (lit.)
Boiling Point	253.8 °C at 760 mmHg
Density	0.862 g/cm³
Flash Point	107.3 °C
Solubility in Water	740.5 g/L (20 °C)
Solubility in DMSO	Slightly soluble
Solubility in Methanol	Slightly soluble
Stability	Stable under normal temperatures and pressures
Storage Conditions	Keep in a dark place, in an inert atmosphere, at room temperature. Store in a tightly closed container, in a cool, dry, well-ventilated area away from incompatible substances.
Safety Precautions	Avoid contact with skin and eyes. Wear appropriate protective equipment. In case of contact, rinse thoroughly with water and seek medical advice if necessary.

Application Areas

Biochemical research: As a derivative of homocysteine, it is used to study the metabolic pathway of thioneification and its association with cardiovascular disease and neurodegenerative diseases such as Alzheimer’s disease.
Drug development: As a potential drug intermediate, it is used to design compounds that regulate homocysteine levels or develop inhibitors for thiolase.
Plant biology research: Low concentrations (such as 50 μ M) can inhibit plant root growth and are used to study the response mechanism of plants to amino acid derivatives.
Metal ion research: can form stable complexes with metal ions to assist in the study of the function of metalloenzymes or metalloproteins.

Storage conditions

Storage conditions: Sealed storage, away from light and moisture, recommended storage temperature of 2-8 ° C (short-term) or -20 ° C (long-term).
Stability: Stable at room temperature and pressure, but avoid environments with strong oxidants, strong acids, or strong bases to prevent decomposition.

Safety precautions

Hazard: It belongs to non hazardous substances (GHS classification), but protective equipment (such as gloves, goggles) should be worn during operation to avoid inhaling dust or skin contact.
Emergency measures:
Inhalation: Transfer to fresh air and maintain unobstructed breathing.
Skin contact: Rinse with plenty of soapy water and seek medical attention if necessary.
Ingestion: Rinse mouth immediately and seek medical help, do not induce vomiting.
Waste disposal: Follow local regulations and it is recommended to handle it through professional institutions

FAQ - Technical & Supply Chain

Q:
Do DL-Homocysteine Thiolactone Hydrochloride and Homocysteine thiolactone HCl refer to the same substance?

A: Yes. These names describe the same hydrochloride salt form and correspond to a single CAS number, indicating identical substance identity.
Q:
Is DL-Homocysteine Thiolactone Hydrochloride used as an industrial intermediate rather than a finished pharmaceutical product?

A: It is typically intended for use as an intermediate in pharmaceutical and biochemical synthesis processes, rather than as a finished dosage form.

Documents

Documents and Product Support

For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.

COA for batch-based quality reference
TDS for key physical and chemical information
SDS / MSDS for handling, storage, and safety reference
Packing information for sample, trial, and bulk orders
Technical communication based on application and specification requirements

Quotation

Information to Confirm Before Quotation

Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.

Product name and CAS number
Application or intended end use
Required purity, grade, or specification
Sample quantity, trial order, or bulk demand
Preferred packing form or net weight
Destination country or port
Required documents or compliance expectations

Storage & Handling

Packaging, Storage, and Handling Notes

Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.

Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.

Supply Support

Sample, Bulk Order and Repeat Supply Support

Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.

For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.

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Amino Acid Derivative Pharmaceutical Intermediate Thiolactone Thiolactone Intermediate

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