D-Glucurone (CAS 32449-92-6), chemically identified as D-glucurono-3,6-lactone, is a naturally occurring cyclic ester functioning as a key active ingredient in functional beverage formulation and hepatoprotective compounds. This white crystalline powder, most widely technically recognized as Glucuronolactone, acts as a precursor for ascorbic acid synthesis and a detoxifying agent that conjugates with toxins in the liver, making it a staple ingredient in energy drinks and recovery supplements. We provide bulk supply of this nutritional grade ingredient with competitive factory pricing to ensure supply stability for beverage and health product manufacturers. Our quality assurance protocols ensure high solubility and purity, making MSDS, TDS, COA available alongside customized specifications to meet food safety or pharmaceutical standards.
D-Glucurone CAS 32449-92-6
- CAS: 32449-92-6
- Synonyms: Glucuronolactone, D-Glucurono-3,6-lactone, Glucuronic acid lactone, D-Glucurono-6,3-lactone, Glucurolactone
- Einecs: 204-506-4
- Molecular Formula: C8H12ClNO3
- Grade: Pharmaceutical grade / Biochemical grade
- Package: 1kg aluminum foil bag; 25kg drum; Custom packaging available
Product Description
D-Glucurone (CAS 32449-92-6) is a high-purity biochemical raw material commonly used in pharmaceuticals, biochemical research, health supplements, and metabolic studies. Manufactured under strict quality control in China, it provides stable purity, consistent batch performance, and reliable supply for global customers.
We offer multiple grades and packaging options to meet laboratory, pilot-scale, and industrial needs. Contact us for detailed specifications and quotations.
Physicochemical Properties
| Property | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥ 98% (customizable 99%) |
| Solubility | Soluble in water; slightly soluble in ethanol |
| Melting Point | 160–165°C (typical range) |
| pH (1% solution) | 3.0–4.0 |
| Odor | Odorless |
| Stability | Stable under normal storage conditions |
| Shelf Life | 24 months under recommended storage |
Applications
1. Pharmaceutical Intermediates
- Used in the synthesis of glucuronic acid derivatives.
- Key raw material for detoxification pathway studies.
2. Biochemical Research
- Applied in metabolic research, enzymatic activity assays, and liver detoxification studies.
3. Nutritional & Functional Ingredients
- Potential component in formulations related to liver health and metabolism.
- Used in R&D for health supplement ingredients.
4. Industrial & Analytical Usage
- Intermediate for fine chemicals.
- Calibration and reference standard for analytical laboratories.
Storage Conditions
- Store in a cool, dry, well-ventilated area.
- Keep container tightly sealed to avoid moisture absorption.
- Recommended storage temperature: 2–8°C.
- Protect from direct sunlight and strong oxidizing agents.
Safety Precautions
- Non-hazardous chemical under normal handling conditions.
- Avoid inhalation of dust; use protective mask and gloves.
- Wash thoroughly after handling.
- Consult MSDS for detailed safety guidelines.
- Keep out of reach of children.

FAQ - Technical & Supply Chain
-
Q:
How does the chemical structure of D-Glucurone (CAS 32449-92-6) relate to Glucuronic Acid?
A: D-Glucurone is the cyclic lactone form of D-glucuronic acid; in aqueous solutions, it exists in equilibrium with the acid form, but the lactone structure (CAS 32449-92-6) is preferred for industrial handling due to its superior stability and rapid absorption kinetics. -
Q:
Is this ingredient primarily intended for pharmaceutical or beverage applications?
A: While originally developed for pharmaceutical hepatoprotection, this specific grade is extensively intended for use in the functional beverage industry (such as energy drinks) to work synergistically with caffeine and taurine.
Documents and Product Support
For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.
- COA for batch-based quality reference
- TDS for key physical and chemical information
- SDS / MSDS for handling, storage, and safety reference
- Packing information for sample, trial, and bulk orders
- Technical communication based on application and specification requirements
Information to Confirm Before Quotation
Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.
- Product name and CAS number
- Application or intended end use
- Required purity, grade, or specification
- Sample quantity, trial order, or bulk demand
- Preferred packing form or net weight
- Destination country or port
- Required documents or compliance expectations
Packaging, Storage, and Handling Notes
Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.
Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.
Sample, Bulk Order and Repeat Supply Support
Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.
For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.



