D-Glucurone (CAS 32449-92-6), chemically identified as D-glucurono-3,6-lactone, is a naturally occurring cyclic ester functioning as a key active ingredient in functional beverage formulation and hepatoprotective compounds. This white crystalline powder, most widely technically recognized as Glucuronolactone, acts as a precursor for ascorbic acid synthesis and a detoxifying agent that conjugates with toxins in the liver, making it a staple ingredient in energy drinks and recovery supplements. We provide bulk supply of this nutritional grade ingredient with competitive factory pricing to ensure supply stability for beverage and health product manufacturers. Our quality assurance protocols ensure high solubility and purity, making MSDS, TDS, COA available alongside customized specifications to meet food safety or pharmaceutical standards.
D-Glucurone CAS 32449-92-6
- CAS: 32449-92-6
- Synonyms: Glucuronolactone, D-Glucurono-3,6-lactone, Glucuronic acid lactone, D-Glucurono-6,3-lactone, Glucurolactone
- Einecs: 251-053-3
- Molecular Formula: C6H8O6
- Grade: Pharmaceutical grade / Biochemical grade
- Package: 1kg aluminum foil bag; 25kg drum; Custom packaging available
Product Description
D-Glucurone (CAS 32449-92-6) is a high-purity biochemical raw material commonly used in pharmaceuticals, biochemical research, health supplements, and metabolic studies. Manufactured under strict quality control in China, it provides stable purity, consistent batch performance, and reliable supply for global customers.
We offer multiple grades and packaging options to meet laboratory, pilot-scale, and industrial needs. Contact us for detailed specifications and quotations.
Physicochemical Properties
| Property | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥ 98% (customizable 99%) |
| Solubility | Soluble in water; slightly soluble in ethanol |
| Melting Point | 160–165°C (typical range) |
| pH (1% solution) | 3.0–4.0 |
| Odor | Odorless |
| Stability | Stable under normal storage conditions |
| Shelf Life | 24 months under recommended storage |
Applications
1. Pharmaceutical Intermediates
- Used in the synthesis of glucuronic acid derivatives.
- Key raw material for detoxification pathway studies.
2. Biochemical Research
- Applied in metabolic research, enzymatic activity assays, and liver detoxification studies.
3. Nutritional & Functional Ingredients
- Potential component in formulations related to liver health and metabolism.
- Used in R&D for health supplement ingredients.
4. Industrial & Analytical Usage
- Intermediate for fine chemicals.
- Calibration and reference standard for analytical laboratories.
Storage Conditions
- Store in a cool, dry, well-ventilated area.
- Keep container tightly sealed to avoid moisture absorption.
- Recommended storage temperature: 2–8°C.
- Protect from direct sunlight and strong oxidizing agents.
Safety Precautions
- Non-hazardous chemical under normal handling conditions.
- Avoid inhalation of dust; use protective mask and gloves.
- Wash thoroughly after handling.
- Consult MSDS for detailed safety guidelines.
- Keep out of reach of children.

FAQ - Technical & Supply Chain
-
Q:
What is D-Glucurone CAS 32449-92-6?
A: D-Glucurone, also known as glucuronolactone, is the cyclic lactone form of D-glucuronic acid. It is a white crystalline powder used in pharmaceutical, biochemical, dietary-supplement and functional-beverage applications. -
Q:
How does D-glucurone relate to glucuronic acid?
A: D-glucurone is the intramolecular ester of D-glucuronic acid. In aqueous solution the lactone can exist in equilibrium with the open acid form, while the crystalline material is supplied as the stable lactone with CAS 32449-92-6. -
Q:
What are the main applications?
A: It is used in energy drinks and functional beverages, dietary supplements, pharmaceutical hepatoprotective formulations, biochemical research and as an intermediate for glucuronic-acid derivatives. -
Q:
Why is glucuronolactone used in energy drinks?
A: It is included as a carbohydrate-related ingredient associated with normal energy metabolism and detoxification support. Formulators should use a grade, purity and dosage consistent with local food and beverage regulations. -
Q:
Which grade and packaging are available?
A: This listing covers pharmaceutical and biochemical grade. It is supplied in 1 kg aluminum-foil bags or 25 kg drums, with custom packaging available on request. -
Q:
What specifications should be checked before ordering?
A: Confirm assay, appearance, melting point, specific rotation, moisture, residue on ignition, heavy metals, residual solvents and microbial limits. Request the current batch analysis, technical data and safety information for the batch. -
Q:
How should D-glucurone be stored and handled?
A: Store in tightly closed containers in a cool, dry, ventilated area away from moisture, heat and incompatible materials. Use dust-control measures and suitable PPE, and follow the safety information for handling and disposal.
Ordering & Documentation
Key information for document requests, quotations, and supply planning.
Documents
COA, TDS, SDS/MSDS and packing details are available on request.
Quotation
Send the CAS number, grade, quantity, packing preference and destination.
Sample & Supply
Support is available for samples, trial orders, bulk and repeat supply.
Storage & Shipping
Product-specific conditions are confirmed before order.
