D-Glucurone (CAS 32449-92-6), commercially recognized as Glucuronolactone, is a naturally occurring metabolite functioning as a key performance ingredient in energy drinks and a hepatoprotective agent in pharmaceuticals. Chemically identified as D-Glucurono-3,6-lactone, this white crystalline powder acts to scavenge toxins by forming conjugates with harmful substances in the liver, facilitating their excretion. As a stable Lactone derivative of glucuronic acid, it is extensively integrated into functional beverages to reduce mental fatigue and improve alertness, as well as into nutritional supplements for joint health and liver detoxification. We ensure bulk supply capabilities for this material, providing access to competitive factory pricing and customized specifications to meet specific mesh sizes and purity standards (e.g., USP/Food Grade). Full technical documentation, including MSDS, TDS, COA, is available to support compliance and safety protocols.
D-Glucurone CAS 32449-92-6
- CAS: 32449-92-6
- Synonyms: D-Glucuronolactone, Glucuronolactone, D-Glucurono-6,3-lactone, Glucuronic acid lactone, D-Glucuronic acid gamma-lactone
- Einecs: 251-053-3
- Molecular Formula: C6H8O6
- Grade: Food Grade
- Package: 25kg Carton Box or Fiber Drum with inner dual PE bags.
Product Description
D-Glucurone, chemically known as D-Glucurono-3,6-Lactone, is a white crystalline powder that is readily soluble in water. Upon entering the body, it is metabolized into glucuronic acid, which binds with toxins in the liver and facilitates their excretion.
Due to its potent anti-fatigue properties, it is extensively used in the beverage industry as a core additive for energy drinks, often formulated alongside Taurine, Caffeine, and B-Vitamins. Our production process adheres to GMP standards, ensuring high purity, low heavy metal content, and consistent crystal size suitable for various blending processes.
Physicochemical Properties
The following specifications reflect our standard Food/Pharma Grade export quality (adhering to USP/BP standards):
| Property | Specification / Value |
|---|---|
| Appearance | White crystalline powder or white crystals |
| Identification | Matches Standard |
| Assay (Purity) | 98.5% ~ 102.0% |
| Melting Point | 170°C – 176°C |
| Specific Rotation [α]20/D | +18.0° ~ +20.0° |
| Solubility | Soluble in water (slowly hydrolyzes); Sparingly soluble in alcohol |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition (Ash) | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
| Arsenic (As) | ≤ 1 ppm |
| Lead (Pb) | ≤ 2 ppm |
| Clarity and Color of Solution | Clear and Colorless |
Applications
D-Glucuronolactone is a versatile ingredient used across multiple industries:
- Functional Beverages (Energy Drinks):
- Widely used as a nutritional additive to boost energy, improve mental alertness, and reduce muscle fatigue.
- Pharmaceuticals & Hepatoprotection:
- Used as a raw material for liver detoxification drugs (“Gantai”). It helps protect the liver from toxins and aids in recovery from hepatitis or alcohol toxicity.
- Dietary Supplements:
- Promotes joint health (as a precursor to chondroitin) and supports overall immune system function.
- Food Additives:
- Used as a nutritional enhancer in various processed foods.
Storage Conditions
- Dryness: The product is stable in crystalline form but can hydrolyze to glucuronic acid in aqueous solution. Keep strictly dry.
- Environment: Store in a cool, dry, and well-ventilated area away from direct sunlight.
- Temperature: Room temperature storage is generally acceptable, but cooler conditions extend shelf life.
- Packaging: Keep container tightly closed when not in use.
- Shelf Life: 24 months from the date of manufacture.
Safety Precautions
- General: D-Glucuronolactone is generally recognized as safe (GRAS) for use in food and beverages.
- Handling: Avoid creating dust. Inhalation of high concentrations of dust may cause mild respiratory irritation.
- Contact: Avoid contact with eyes and skin. Wear standard safety glasses and gloves during industrial handling.
- First Aid:
- If in eyes: Rinse cautiously with water for several minutes.
- If on skin: Wash with plenty of soap and water.
FAQ - Technical & Supply Chain
-
Q:
How is D-Glucurone CAS 32449-92-6 chemically related to D-Glucuronic Acid?
A: D-Glucurone (CAS 32449-92-6) is the cyclic ester (lactone) form of D-glucuronic acid, chemically formed by the removal of water, which provides better stability and shelf-life in dry powder formulations compared to the free acid. -
Q:
Is this ingredient the same one used in popular energy drinks?
A: Yes, this material is the exact bioactive ingredient (Glucuronolactone) found in leading energy drink brands, typically combined with caffeine and taurine to support mental performance and detoxification.
Documents and Product Support
For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.
- COA for batch-based quality reference
- TDS for key physical and chemical information
- SDS / MSDS for handling, storage, and safety reference
- Packing information for sample, trial, and bulk orders
- Technical communication based on application and specification requirements
Information to Confirm Before Quotation
Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.
- Product name and CAS number
- Application or intended end use
- Required purity, grade, or specification
- Sample quantity, trial order, or bulk demand
- Preferred packing form or net weight
- Destination country or port
- Required documents or compliance expectations
Packaging, Storage, and Handling Notes
Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.
Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.
Sample, Bulk Order and Repeat Supply Support
Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.
For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.








