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    Related: Life Science Chemical ARA D-Mannose
    • D-Glucurone CAS 32449-92-6

    D-Glucurone CAS 32449-92-6

    D-Glucurone (CAS 32449-92-6), commercially recognized as Glucuronolactone, is a naturally occurring metabolite functioning as a key performance ingredient in energy drinks and a hepatoprotective agent in pharmaceuticals. Chemically identified as D-Glucurono-3,6-lactone, this white crystalline powder acts to scavenge toxins by forming conjugates with harmful substances in the liver, facilitating their excretion. As a stable Lactone derivative of glucuronic acid, it is extensively integrated into functional beverages to reduce mental fatigue and improve alertness, as well as into nutritional supplements for joint health and liver detoxification. We ensure bulk supply capabilities for this material, providing access to competitive factory pricing and customized specifications to meet specific mesh sizes and purity standards (e.g., USP/Food Grade). Full technical documentation, including MSDS, TDS, COA, is available to support compliance and safety protocols.

    • CAS: 32449-92-6
    • Synonyms: D-Glucuronolactone, Glucuronolactone, D-Glucurono-6,3-lactone, Glucuronic acid lactone, D-Glucuronic acid gamma-lactone
    • Einecs: 251-053-3
    • Molecular Formula: C6H8O6
    • Grade: Food Grade
    • Package: 25kg Carton Box or Fiber Drum with inner dual PE bags.
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    Product Description

    D-Glucurone, chemically known as D-Glucurono-3,6-Lactone, is a white crystalline powder that is readily soluble in water. Upon entering the body, it is metabolized into glucuronic acid, which binds with toxins in the liver and facilitates their excretion.

    Due to its potent anti-fatigue properties, it is extensively used in the beverage industry as a core additive for energy drinks, often formulated alongside Taurine, Caffeine, and B-Vitamins. Our production process adheres to GMP standards, ensuring high purity, low heavy metal content, and consistent crystal size suitable for various blending processes.

    1 Physicochemical Properties
    2 Applications
    3 Storage Conditions
    4 Safety Precautions

    Physicochemical Properties

    The following specifications reflect our standard Food/Pharma Grade export quality (adhering to USP/BP standards):

    PropertySpecification / Value
    AppearanceWhite crystalline powder or white crystals
    IdentificationMatches Standard
    Assay (Purity)98.5% ~ 102.0%
    Melting Point170°C – 176°C
    Specific Rotation [α]20/D+18.0° ~ +20.0°
    SolubilitySoluble in water (slowly hydrolyzes); Sparingly soluble in alcohol
    Loss on Drying≤ 0.5%
    Residue on Ignition (Ash)≤ 0.1%
    Heavy Metals≤ 10 ppm
    Arsenic (As)≤ 1 ppm
    Lead (Pb)≤ 2 ppm
    Clarity and Color of SolutionClear and Colorless

    Applications

    D-Glucuronolactone is a versatile ingredient used across multiple industries:

    1. Functional Beverages (Energy Drinks):
      • Widely used as a nutritional additive to boost energy, improve mental alertness, and reduce muscle fatigue.
    2. Pharmaceuticals & Hepatoprotection:
      • Used as a raw material for liver detoxification drugs (“Gantai”). It helps protect the liver from toxins and aids in recovery from hepatitis or alcohol toxicity.
    3. Dietary Supplements:
      • Promotes joint health (as a precursor to chondroitin) and supports overall immune system function.
    4. Food Additives:
      • Used as a nutritional enhancer in various processed foods.

    Storage Conditions

    • Dryness: The product is stable in crystalline form but can hydrolyze to glucuronic acid in aqueous solution. Keep strictly dry.
    • Environment: Store in a cool, dry, and well-ventilated area away from direct sunlight.
    • Temperature: Room temperature storage is generally acceptable, but cooler conditions extend shelf life.
    • Packaging: Keep container tightly closed when not in use.
    • Shelf Life: 24 months from the date of manufacture.

    Safety Precautions

    • General: D-Glucuronolactone is generally recognized as safe (GRAS) for use in food and beverages.
    • Handling: Avoid creating dust. Inhalation of high concentrations of dust may cause mild respiratory irritation.
    • Contact: Avoid contact with eyes and skin. Wear standard safety glasses and gloves during industrial handling.
    • First Aid:
      • If in eyes: Rinse cautiously with water for several minutes.
      • If on skin: Wash with plenty of soap and water.

    FAQ - Technical & Supply Chain

    • Q:

      What is D-Glucurone CAS 32449-92-6?

      A: D-Glucurone CAS 32449-92-6 is the lactone form of D-glucuronic acid, commonly called D-glucuronolactone or glucuronolactone. It has the molecular formula C6H8O6 and is supplied as a white crystalline powder.
    • Q:

      How is D-Glucurone related to D-glucuronic acid?

      A: It is the cyclic ester formed from D-glucuronic acid by internal dehydration, which makes it more stable as a dry solid. In water it slowly hydrolyzes back toward the open acid form.
    • Q:

      Why is D-Glucuronolactone used in energy drinks and beverages?

      A: It is a water-soluble ingredient often formulated with taurine, caffeine, and B vitamins in energy and functional beverages. In product development it is used for its identity as glucuronolactone and its compatibility with clear, acidic beverage systems.
    • Q:

      What food or pharmaceutical quality specifications apply?

      A: Typical specifications include assay, melting point around 170-176 C, specific rotation about +18 to +20 degrees, low loss on drying, low ash, and controlled heavy metals. Food and pharma grades may differ in documentation and impurity limits.
    • Q:

      What solubility and handling points should formulators know?

      A: D-Glucurone is readily soluble in water but only sparingly soluble in alcohol, and aqueous solutions slowly hydrolyze. Store it sealed in a cool, dry place to protect powder flow and crystalline appearance.

    Ordering & Documentation

    Key information for document requests, quotations, and supply planning.

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    COA, TDS, SDS/MSDS and packing details are available on request.

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