Benzethonium Chloride (CAS 121-54-0, EC 204-479-9) is a cationic quaternary ammonium ingredient supplied for personal-care, hygiene and specialty formulation projects. COA, TDS and SDS are available for the supplied grade. Contact us with your application or target specification, quantity and destination for a quotation.
Benzethonium Chloride CAS 121-54-0
- CAS: 121-54-0
- Synonyms: Benzethonium chloride; Hyamine; Hyamine 1622; Phemerol chloride
- Einecs: 204-479-9
- Molecular Formula: C₂₇H₄₂ClNO₂
- Grade: Benzethonium Chloride grades defined by assay, water or loss on drying, related-substance limits and physical form
- Package: We specify Benzethonium Chloride packaging in our quotation according to the selected grade, quantity and destination.
Product Description
Product Overview
Benzethonium Chloride is a cationic quaternary ammonium ingredient used in selected personal-care, hygiene and specialty formulations. Because antimicrobial and antiseptic uses can be regulated, confirm the supplied grade and destination-market requirements before formulation.
Assess compatibility with anionic ingredients and confirm the permitted use level and documentation for the destination market.
For Benzethonium Chloride, distinguish HPLC area purity from assay determined by titration, and specify the reporting basis; these measurements are not interchangeable. Water or loss on drying and related-substance limits also matter when matching a purchasing specification. We can provide HPLC chromatographic data with the method and reporting basis for the selected grade.
Hyamine 1622 and Phemerol chloride are names associated with benzethonium chloride. A prepared Hyamine 1622 titrant is a solution with a stated concentration, so its concentration cannot be compared directly with the assay of solid raw material. Specify the required physical form, concentration and test method when requesting a quotation.
Product Information / Specifications
| Product Name | Benzethonium Chloride |
| CAS Number | 121-54-0 |
| Product Identity | Cationic antimicrobial formulation ingredient |
| Chemical Class | Quaternary ammonium compound |
| Synonym | Hyamine |
| Molecular Formula | C27H42ClNO2 |
| Molecular Weight | 448.09 g/mol |
| Supply Form | Typically supplied as solid material, depending on supplied grade |
| Grade Selection Checks | Benzethonium Chloride grades defined by assay, water or loss on drying, related-substance limits and physical form |
| Technical Documents | We can provide COA, TDS and SDS for the supplied Benzethonium Chloride grade. |
Physical & Chemical Properties
| Appearance | Typically supplied as white to off-white powder or crystalline solid |
| Solubility | Water soluble; solubility behavior may vary with grade and solvent system |
| Functional Character | Cationic, antimicrobial, and surface-active |
| Melting Range | Typically reported around 159–165°C depending on specification |
| Assay Requirements | Benzethonium Chloride assay values are reported with the test method and the basis of calculation, such as the dried-substance basis. |
Applications
- Selected personal-care or hygiene formulations where the grade and permitted use are confirmed.
- Regulated antimicrobial or antiseptic formulations only after destination-market and product-category review.
- Oral-care formulations subject to ingredient compatibility and market-specific authorization.
- Wet-wipe and surface-hygiene formulations where cationic compatibility and permitted use are confirmed.
- Specialty formulations requiring a defined quaternary ammonium ingredient and documented impurity limits.
Comparing Related Formulation Ingredients
Benzalkonium chloride is another quaternary ammonium ingredient, but it is typically an alkyl-chain mixture rather than the single defined benzethonium compound. Compare active content, composition and compatibility in the intended formulation instead of treating the two materials as identical.
For other antimicrobial formulation projects, chlorhexidine digluconate is a bisbiguanide salt, polyhexamethylene biguanide (PHMB) is a polymeric biguanide, and chloroxylenol (PCMX) is a phenolic ingredient. They are comparison materials, not direct substitutes or automatic blend partners; selection depends on formulation compatibility, required performance and the intended market.
Packaging
We specify Benzethonium Chloride packaging in our quotation according to the selected grade, quantity and destination.
Storage Conditions
Store in a cool, dry, and well-ventilated place in tightly closed containers. Protect from excessive heat, direct light, and moisture exposure.
Storage conditions may be adjusted according to the supplied grade and specification control requirements.
Safety Precautions
- Avoid contact with skin, eyes, and clothing during handling.
- Use appropriate personal protective equipment and suitable workplace ventilation.
- Avoid incompatible materials during formulation development and processing.
- Follow the Benzethonium Chloride SDS and workplace handling procedures for storage, transfer and disposal.
- Dispose of residues and empty packaging in accordance with local regulatory requirements.
FAQ - Technical & Supply Chain
-
Q:
Is Benzethonium Chloride the same as Benzalkonium Chloride?
A: No. Benzethonium Chloride (CAS 121-54-0) is a defined quaternary ammonium compound, whereas Benzalkonium Chloride is commonly a mixture of alkylbenzyldimethylammonium chlorides. They should not be exchanged without confirming the intended formulation and applicable requirements. -
Q:
Is Benzethonium Chloride compatible with anionic surfactants?
A: As a cationic quaternary ammonium ingredient, Benzethonium Chloride can interact with soaps and anionic surfactants. This can alter solution clarity or reduce the intended functional contribution; assess compatibility in the complete formula before selecting it. -
Q:
Which grade details should accompany Benzethonium Chloride selection?
A: Confirm the material identity, assay basis, water or loss-on-drying limit, appearance, physical form and any application-specific impurity limits. The final formula and destination-market requirements determine whether a particular grade and its documentation are suitable.
Ordering & Documentation
Key information for document requests, quotations, and supply planning.
Documents
Tell us which documents your procurement team needs. Before an order, we will check whether the quoted source can provide them for the offered lot.
Quotation
Send the CAS number, grade, quantity, packing preference and destination.
Sample & Supply
Ask whether samples, trial quantities or repeat orders are possible. We will check each request against the sourced product and current offer.
Storage & Shipping
Product-specific conditions are confirmed before order.








