Benzethonium Chloride (CAS 121-54-0) is supplied as a cationic antimicrobial formulation ingredient used in personal care, topical antiseptic, and oral care systems. It is commonly selected where preservative, antimicrobial, and cationic surface-active performance are required in formulated products. COA, TDS, and SDS may be provided according to the supplied grade.
Benzethonium Chloride CAS 121-54-0Benzethonium Chloride (CAS 121-54-0)
- CAS: 121-54-0
- Synonyms: Hyamine 1622
- Einecs: 204-479-9
- Molecular Formula: C₂₇H₄₂ClNO₂
- Grade: 99%
- Package: 25kg/drum, or as required
Product Description
Product Overview
Benzethonium Chloride is supplied as a cationic antimicrobial formulation ingredient for personal care, topical antiseptic, and oral care systems. It is commonly used where preservative support, antimicrobial performance, and cationic surface activity are required in finished formulations.
This material is suitable for formulations that require a quaternary ammonium ingredient with broad antimicrobial functionality and good compatibility with appropriately designed aqueous systems.
Product Information / Specifications
| Product Name | Benzethonium Chloride |
| CAS Number | 121-54-0 |
| Product Identity | Cationic antimicrobial formulation ingredient |
| Chemical Class | Quaternary ammonium compound |
| Synonym | Hyamine |
| Molecular Formula | C27H42ClNO2 |
| Molecular Weight | 448.09 |
| Supply Form | Typically supplied as solid material, depending on supplied grade |
| Grade Availability | Available according to grade and formulation requirement |
| Technical Documents | COA, TDS, and SDS may be provided according to the supplied grade |
Physical & Chemical Properties
| Appearance | Typically supplied as white to off-white powder or crystalline solid |
| Solubility | Water soluble; solubility behavior may vary with grade and solvent system |
| Functional Character | Cationic, antimicrobial, and surface-active |
| Melting Range | Typically reported around 159–165°C depending on specification |
| Typical Purity | Available according to supplied grade and specification |
Applications
- Personal care preservative systems where antimicrobial protection is required in compatible formulations.
- Topical antiseptic formulations developed for regulated external-use applications according to the target market framework.
- Oral care formulations where cationic antimicrobial functionality is required in rinse or hygiene systems.
- Wet wipe and hygiene formulations requiring a quaternary ammonium antimicrobial ingredient.
- Specialty pharmaceutical formulations where preservative or antimicrobial support is needed according to formulation design.
Packaging
Packaging may vary by supplied grade and formulation use. The material is typically packed in sealed containers suitable for moisture-sensitive and specification-controlled chemical ingredients.
Storage Conditions
Store in a cool, dry, and well-ventilated place in tightly closed containers. Protect from excessive heat, direct light, and moisture exposure.
Storage conditions may be adjusted according to the supplied grade and specification control requirements.
Safety Precautions
- Avoid contact with skin, eyes, and clothing during handling.
- Use appropriate personal protective equipment and suitable workplace ventilation.
- Avoid incompatible materials during formulation development and processing.
- Follow the applicable SDS and site handling procedures for storage, transfer, and disposal.
- Dispose of residues and empty packaging in accordance with local regulatory requirements.
FAQ - Technical & Supply Chain
-
Q:
What purity grades are available for Benzethonium Chloride?
A: Benzethonium Chloride is available in USP/NF and EP grades, with purity ≥98%. Custom specifications can be accommodated upon request. -
Q:
What are the primary applications of Benzethonium Chloride?
A: Benzethonium Chloride (Hyamine 1622) is widely used as a cationic antimicrobial preservative in personal care products such as hand sanitizers, soaps, and topical formulations. It is also employed as a disinfectant in healthcare settings and hard-surface cleaning solutions. -
Q:
How should Benzethonium Chloride be stored?
A: Benzethonium Chloride should be stored in a cool, dry environment in tightly sealed containers, away from direct sunlight and moisture. Proper storage ensures product stability and extends shelf life. -
Q:
What safety precautions are required when handling Benzethonium Chloride?
A: Standard safety measures include wearing protective gloves, safety goggles, and appropriate lab attire. Avoid dust inhalation and contact with eyes. Refer to the Safety Data Sheet (SDS) for comprehensive handling and first-aid instructions. -
Q:
Does Benzethonium Chloride comply with regulatory standards?
A: Benzethonium Chloride is compliant with USP/NF and EP pharmacopoeial standards. It is FDA-approved for use in over-the-counter antiseptic products. Our manufacturing facilities are ISO 9001 certified. -
Q:
Can I request a sample or COA before placing an order?
A: Yes, we offer free samples for quality evaluation, and a Certificate of Analysis (COA) is available for all batches upon request. Contact our sales team for sample and documentation requests.
Documents and Product Support
For product review and sourcing evaluation, supporting documents can be coordinated according to the product type, inquiry stage, and order requirements.
- COA for batch-based quality reference
- TDS for key physical and chemical information
- SDS / MSDS for handling, storage, and safety reference
- Packing information for sample, trial, and bulk orders
- Technical communication based on application and specification requirements
Information to Confirm Before Quotation
Clear sourcing information helps reduce specification mismatch and allows a more accurate quotation before sample or bulk order discussion.
- Product name and CAS number
- Application or intended end use
- Required purity, grade, or specification
- Sample quantity, trial order, or bulk demand
- Preferred packing form or net weight
- Destination country or port
- Required documents or compliance expectations
Packaging, Storage, and Handling Notes
Packaging form, storage conditions, shelf life, and shipment arrangements should be confirmed according to the product characteristics, package size, and destination requirements.
Before order confirmation, buyers are advised to review the corresponding product documents and confirm whether any special storage, labeling, or handling requirements apply.
Sample, Bulk Order and Repeat Supply Support
Support can be arranged for sample discussion, bulk supply planning, packaging confirmation, and routine sourcing communication based on the actual product and order requirements.
For repeat-use formulations or long-term procurement plans, buyers may discuss specification consistency, packaging preferences, delivery expectations, and document coordination in advance.










