Benzethonium Chloride (CAS 121-54-0, EC 204-479-9) is a quaternary ammonium ingredient used in personal-care, hygiene and specialty formulations where cationic surface activity and antimicrobial performance are required. It should not be confused with benzalkonium chloride or methylbenzethonium chloride. Purity or active content, physical form and packaging should be confirmed for the selected grade. COA, TDS and SDS may be provided on request.
Benzethonium Chloride CAS 121-54-0
- CAS: 121-54-0
- Synonyms: Benzethonium chloride; Hyamine; Hyamine 1622; Phemerol chloride
- Einecs: 204-479-9
- Molecular Formula: C₂₇H₄₂ClNO₂
- Grade: Confirm assay or active content, water, related substances, solubility and physical form
- Package: Confirm current packaging for the selected grade and destination
Product Description
Product Overview
Benzethonium Chloride is a cationic quaternary ammonium ingredient used in selected personal-care, hygiene and specialty formulations. Because antimicrobial and antiseptic uses can be regulated, confirm the supplied grade and destination-market requirements before formulation.
Assess compatibility with anionic ingredients and confirm the permitted use level and documentation for the destination market.
Product Information / Specifications
| Product Name | Benzethonium Chloride |
| CAS Number | 121-54-0 |
| Product Identity | Cationic antimicrobial formulation ingredient |
| Chemical Class | Quaternary ammonium compound |
| Synonym | Hyamine |
| Molecular Formula | C27H42ClNO2 |
| Molecular Weight | 448.09 |
| Supply Form | Typically supplied as solid material, depending on supplied grade |
| Grade Availability | Confirm assay or active content, water, related substances, solubility and physical form |
| Technical Documents | COA, TDS, and SDS may be provided according to the supplied grade |
Physical & Chemical Properties
| Appearance | Typically supplied as white to off-white powder or crystalline solid |
| Solubility | Water soluble; solubility behavior may vary with grade and solvent system |
| Functional Character | Cationic, antimicrobial, and surface-active |
| Melting Range | Typically reported around 159–165°C depending on specification |
| Typical Purity | Available according to supplied grade and specification |
Applications
- Selected personal-care or hygiene formulations where the grade and permitted use are confirmed.
- Regulated antimicrobial or antiseptic formulations only after destination-market and product-category review.
- Oral-care formulations subject to ingredient compatibility and market-specific authorization.
- Wet-wipe and surface-hygiene formulations where cationic compatibility and permitted use are confirmed.
- Specialty formulations requiring a defined quaternary ammonium ingredient and documented impurity limits.
Packaging
Confirm current packaging for the selected grade and destination
Storage Conditions
Store in a cool, dry, and well-ventilated place in tightly closed containers. Protect from excessive heat, direct light, and moisture exposure.
Storage conditions may be adjusted according to the supplied grade and specification control requirements.
Safety Precautions
- Avoid contact with skin, eyes, and clothing during handling.
- Use appropriate personal protective equipment and suitable workplace ventilation.
- Avoid incompatible materials during formulation development and processing.
- Follow the applicable SDS and site handling procedures for storage, transfer, and disposal.
- Dispose of residues and empty packaging in accordance with local regulatory requirements.
FAQ - Technical & Supply Chain
-
Q:
Is Benzethonium Chloride the same as Benzalkonium Chloride?
A: No. Benzethonium Chloride (CAS 121-54-0) is a defined quaternary ammonium compound, whereas Benzalkonium Chloride is commonly a mixture of alkylbenzyldimethylammonium chlorides. They should not be exchanged without confirming the intended formulation and applicable requirements. -
Q:
Is Benzethonium Chloride compatible with anionic surfactants?
A: As a cationic quaternary ammonium ingredient, Benzethonium Chloride can interact with soaps and anionic surfactants. This can alter solution clarity or reduce the intended functional contribution; assess compatibility in the complete formula before selecting it. -
Q:
Which grade details should accompany Benzethonium Chloride selection?
A: Confirm the material identity, assay basis, water or loss-on-drying limit, appearance, physical form and any application-specific impurity limits. The final formula and destination-market requirements determine whether a particular grade and its documentation are suitable.
Ordering & Documentation
Key information for document requests, quotations, and supply planning.
Documents
COA, TDS, SDS/MSDS and packing details are available on request.
Quotation
Send the CAS number, grade, quantity, packing preference and destination.
Sample & Supply
Support is available for samples, trial orders, bulk and repeat supply.
Storage & Shipping
Product-specific conditions are confirmed before order.








