What is Chloroxylenol PCMX CAS 88-04-0?

Chloroxylenol PCMX CAS 88-04-0 is 4-chloro-3,5-dimethylphenol, a substituted phenol with the molecular formula C8H9ClO and molecular weight 156.61 g/mol. It is used as an antimicrobial active in personal care and household disinfectant products.

Why is PCMX used in antiseptic soaps and liquid disinfectants?

PCMX provides broad antimicrobial activity and is compatible with many surfactant systems. It is commonly formulated with solubilizers such as alcohol or pine oil because its water solubility is low.

What are the typical physical specifications for Chloroxylenol?

Commercial material is generally a white or cream crystalline powder with a characteristic phenolic odor, assay of about 98.5% or higher, and a melting point around 114-116 C. It is more soluble in organic solvents and alkaline solution than in water.

What is the antimicrobial spectrum of PCMX?

It is active against many Gram-positive bacteria and is used for antibacterial applications, but it is less effective against some Gram-negative organisms and bacterial spores. For finished formulations, use level and contact time should be based on the intended product and applicable testing.

What handling precautions apply to Chloroxylenol PCMX?

PCMX may be harmful if swallowed and can irritate the eyes and skin, with potential for skin sensitization. Handle with appropriate PPE, provide ventilation, and follow local regulations for storage and waste disposal.

Chloroxylenol PCMX CAS 88-04-0

Chloroxylenol (CAS 88-04-0), commonly abbreviated as PCMX, is a secure and efficient antimicrobial agent utilized as the active ingredient in iconic antiseptic liquids and antibacterial soaps. Chemically identified as 4-Chloro-3,5-dimethylphenol, this white to off-white crystalline powder functions by disrupting the cell membrane potentials of bacteria, exhibiting potent activity against Gram-positive strains. As a stable Halogenated phenol derivative, it is extensively integrated into medical disinfectants, household sanitizers, and personal care products like deodorants and hand washes to ensure hygiene and infection control. We ensure bulk supply capabilities for this material, providing access to competitive factory pricing and customized specifications to meet specific solubility and mesh size requirements. Full technical documentation, including MSDS, TDS, COA, is available to support compliance and safety protocols.

CAS: 88-04-0
Synonyms: PCMX, 4-Chloro-3,5-dimethylphenol, p-Chloro-m-xylenol, 4-Chloro-3,5-xylenol, Para-chloro-meta-xylenol
Einecs: 201-793-8
Molecular Formula: C8H9ClO
Grade: Cosmetic Grade / USP / BP Grade
Package: 25kg/Fiber Drum or as per customer request

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Product Description

Chloroxylenol (PCMX) is a secure, high-efficient, broad-spectrum, and low-toxic antiseptic agent. It is a highly effective antimicrobial chemical compound used to control bacteria, algae, and fungi. PCMX is widely recognized for its excellent chemical stability and does not lose activity in standard storage conditions. It is compatible with a wide range of surfactants and is the core active ingredient in many well-known antibacterial soaps, clean-safe liquids, and general disinfectants. Our product is manufactured to meet strict international standards, ensuring low impurity levels and high whiteness suitable for premium cosmetic and medical applications.

1 Physicochemical Properties

2 Applications

3 Storage Conditions

4 Safety Precautions

Physicochemical Properties

The following specifications represent our standard export quality control parameters:

Test Item	Specification / Standard
Appearance	White or off-white crystalline powder
Assay (Purity)	≥ 98.5%
Melting Point	114°C – 116°C
Water Content	≤ 0.5%
Residue on Ignition	≤ 0.1%
Iron (Fe)	≤ 50 ppm
Solubility	Soluble in alcohol, ether, benzene, terpenes; Insoluble in water
Odor	Characteristic phenolic odor
pH Value	Neutral to slightly acidic
Stability	Stable under normal temperatures and pressures

Applications

Chloroxylenol (PCMX) is versatile and used across various industries due to its potent bactericidal properties:

Medical & Hospitals:
- Used as a skin disinfectant and surgical instrument sanitizer.
- Active ingredient in medical-grade antibacterial liquids (e.g., wound cleaners).
Personal Care & Cosmetics:
- Antibacterial Soap: A key ingredient in solid and liquid hand soaps.
- Hair Care: Used in anti-dandruff shampoos.
- Hygiene: Foot care products, deodorants, and hand sanitizers.
- Recommended dosage in cosmetics: 0.2% – 1.0%.
Household Daily Chemicals:
- Laundry disinfectants and fabric sanitizers.
- Floor cleaners and surface disinfectants.
Industrial Applications:
- Preservative in glues, paints, textiles, paper making, and leather processing to prevent mildew and bacterial growth.

For a different antimicrobial active that requires separate application and regulatory review, see Triclosan.

Storage Conditions

Temperature: Store in a cool, dry place generally below 30°C.
Environment: Keep container tightly closed in a well-ventilated area.
Protection: Protect from direct sunlight, moisture, and heat sources.
Compatibility: Keep away from strong oxidizing agents and strong bases.

Safety Precautions

Handling: Wear appropriate personal protective equipment (PPE), including safety glasses, gloves, and a dust mask to avoid inhalation of powder.
Skin Contact: May cause mild skin irritation or allergic reactions in sensitive individuals. Wash thoroughly with soap and water after handling.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do.
Disposal: Dispose of contents/container in accordance with local regulations. Do not release directly into the environment in large quantities.

FAQ - Technical & Supply Chain

Q:
What is Chloroxylenol PCMX CAS 88-04-0?

A: Chloroxylenol PCMX CAS 88-04-0 is 4-chloro-3,5-dimethylphenol, a substituted phenol with the molecular formula C8H9ClO and molecular weight 156.61 g/mol. It is used as an antimicrobial active in personal care and household disinfectant products.
Q:
Why is PCMX used in antiseptic soaps and liquid disinfectants?

A: PCMX provides broad antimicrobial activity and is compatible with many surfactant systems. It is commonly formulated with solubilizers such as alcohol or pine oil because its water solubility is low.
Q:
What are the typical physical specifications for Chloroxylenol?

A: Commercial material is generally a white or cream crystalline powder with a characteristic phenolic odor, assay of about 98.5% or higher, and a melting point around 114-116 C. It is more soluble in organic solvents and alkaline solution than in water.
Q:
What is the antimicrobial spectrum of PCMX?

A: It is active against many Gram-positive bacteria and is used for antibacterial applications, but it is less effective against some Gram-negative organisms and bacterial spores. For finished formulations, use level and contact time should be based on the intended product and applicable testing.
Q:
What handling precautions apply to Chloroxylenol PCMX?

A: PCMX may be harmful if swallowed and can irritate the eyes and skin, with potential for skin sensitization. Handle with appropriate PPE, provide ventilation, and follow local regulations for storage and waste disposal.

Ordering & Documentation

Key information for document requests, quotations, and supply planning.

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COA, TDS, SDS/MSDS and packing details are available on request.

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Sample & Supply

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Storage & Shipping

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