What is Triclosan CAS 3380-34-5?

Triclosan CAS 3380-34-5 is a polychloro phenoxy phenol with the molecular formula C12H7Cl3O2 and molecular weight 289.55 g/mol. It is used as an antimicrobial active in select personal care, oral care and hard-surface products.

What are the typical physical and solubility properties of Triclosan?

Triclosan is generally a white crystalline powder with a melting point around 55-60 C. It has low water solubility and is more soluble in organic solvents such as ethanol, methanol, acetone and propylene glycol.

In which applications is Triclosan commonly used?

It is used in personal care products, oral care products, detergents and medical or institutional disinfectants where local regulations permit. Some consumer wash and food-contact uses are restricted or prohibited in certain markets, so formulators should verify the end-use status.

What quality and storage points are important for Triclosan?

High-purity grades are typically controlled for assay, melting point, loss on drying, ash, heavy metals and chlorophenol impurities. Store the material sealed in a cool, dry area and avoid conditions that could cause clumping or contamination.

Triclosan CAS 3380-34-5

Triclosan, CAS 3380-34-5, is a broad-spectrum antimicrobial and antifungal active supplied for oral care, personal care, detergents, medical disinfectants and functional materials where regulations permit. Confirm the required grade and specification, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 3380-34-5
Synonyms: 5-Chloro-2-(2,4-dichlorophenoxy)phenol, Trichlorohydroxydiphenyl ether
Einecs: 222-182-2
Molecular Formula: C₁₂H₇Cl₃O₂
Grade: Cosmetic Grade / USP / BP Grade
Package: 25kg/Fiber Drum with double inner plastic lining

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Product Description

Triclosan, CAS 3380-34-5, is a polychloro phenoxy phenol with broad-spectrum antibacterial and antifungal activity.

Synonyms: 5-Chloro-2-(2,4-dichlorophenoxy)phenol; Trichlorohydroxydiphenyl ether.

CAS: 3380-34-5.

It has a molecular weight of 289.55 g/mol and appears as a white crystalline powder with a faint aromatic odor.

It has an HPLC purity of not less than 99.0–99.5% and a melting point of about 56–58 °C.

It has low water solubility and is more soluble in ethanol, methanol, acetone and propylene glycol.

It is active against Gram-positive bacteria, many Gram-negative bacteria, and some fungi and yeasts.

It is used in toothpaste and mouthwash to reduce plaque and gingivitis.

It is used in antibacterial facial cleansers, acne creams, deodorants and hand hygiene products.

It is used in antibacterial dishwashing liquids, laundry detergents, fabric softeners, surface disinfectants and cleaning wipes.

It is used in surgical scrubs, preoperative skin preparations and medical instrument disinfectants.

It is used as an antimicrobial additive in textiles, plastics and polymers to prevent bacterial growth on surfaces.

Some consumer wash and food-contact uses are restricted or prohibited in certain markets, so end-use status must be verified.

Confirm appearance, HPLC purity, melting point, loss on drying, ash, heavy metals, 4-chlorophenol, 2,4-dichlorophenol, solubility and pH.

Store below 40 °C in a cool, dry, well-ventilated warehouse, protected from direct sunlight and strong UV sources.

Keep containers tightly sealed when not in use to prevent contamination and oxidation.

Confirm packaging with the requested quantity and destination requirements.

The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.

For an RFQ, state the intended use, required grade and specification, quantity, packaging, destination and document needs.

FAQ - Technical & Supply Chain

Q:
What is Triclosan CAS 3380-34-5?

A: Triclosan CAS 3380-34-5 is a polychloro phenoxy phenol with the molecular formula C12H7Cl3O2 and molecular weight 289.55 g/mol. It is used as an antimicrobial active in select personal care, oral care and hard-surface products.
Q:
What are the typical physical and solubility properties of Triclosan?

A: Triclosan is generally a white crystalline powder with a melting point around 55-60 C. It has low water solubility and is more soluble in organic solvents such as ethanol, methanol, acetone and propylene glycol.
Q:
What type of antimicrobial activity does Triclosan provide?

A: Triclosan is a broad-spectrum antibacterial and antifungal agent with activity against Gram-positive bacteria, many Gram-negative bacteria, and some fungi and yeasts. Performance in a finished product depends on concentration, formulation and the target microorganism.
Q:
In which applications is Triclosan commonly used?

A: It is used in personal care products, oral care products, detergents and medical or institutional disinfectants where local regulations permit. Some consumer wash and food-contact uses are restricted or prohibited in certain markets, so formulators should verify the end-use status.
Q:
What quality and storage points are important for Triclosan?

A: High-purity grades are typically controlled for assay, melting point, loss on drying, ash, heavy metals and chlorophenol impurities. Store the material sealed in a cool, dry area and avoid conditions that could cause clumping or contamination.

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