What is Triclosan CAS 3380-34-5?

Triclosan CAS 3380-34-5 is a polychloro phenoxy phenol with the molecular formula C12H7Cl3O2 and molecular weight 289.55 g/mol. It is used as an antimicrobial active in select personal care, oral care and hard-surface products.

What are the typical physical and solubility properties of Triclosan?

Triclosan is generally a white crystalline powder with a melting point around 55-60 C. It has low water solubility and is more soluble in organic solvents such as ethanol, methanol, acetone and propylene glycol.

What type of antimicrobial activity does Triclosan provide?

Triclosan is a broad-spectrum antibacterial and antifungal agent with activity against Gram-positive bacteria, many Gram-negative bacteria, and some fungi and yeasts. Performance in a finished product depends on concentration, formulation and the target microorganism.

In which applications is Triclosan commonly used?

It is used in personal care products, oral care products, detergents and medical or institutional disinfectants where local regulations permit. Some consumer wash and food-contact uses are restricted or prohibited in certain markets, so formulators should verify the end-use status.

What quality and storage points are important for Triclosan?

High-purity grades are typically controlled for assay, melting point, loss on drying, ash, heavy metals and chlorophenol impurities. Store the material sealed in a cool, dry area and avoid conditions that could cause clumping or contamination.

Triclosan CAS 3380-34-5

Triclosan (CAS 3380-34-5) is a broad-spectrum antimicrobial agent utilized as a highly effective preservative and antiseptic in oral care products and industrial sanitizers. Chemically identified as 2,4,4'-Trichloro-2'-hydroxydiphenyl ether, this white crystalline powder functions to inhibit bacterial fatty acid synthesis, providing durable protection against Gram-positive and Gram-negative bacteria as well as fungi. As a stable Chlorinated aromatic ether, it is extensively integrated into therapeutic toothpastes (for gingivitis control), deodorants, and medical-grade textile treatments to prevent microbial growth and odor generation. We ensure bulk supply capabilities for this material, providing access to competitive factory pricing and customized specifications to meet specific purity standards (e.g., USP/BP grade). Full technical documentation, including MSDS, TDS, COA, is available to support compliance and safety protocols.

CAS: 3380-34-5
Synonyms: 5-Chloro-2-(2,4-dichlorophenoxy)phenol, Trichlorohydroxydiphenyl ether
Einecs: 222-182-2
Molecular Formula: C12H7Cl3O2
Grade: Cosmetic Grade / USP / BP Grade
Package: 25kg/Fiber Drum with double inner plastic lining

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Product Description

Triclosan is a highly effective, broad-spectrum antimicrobial and antifungal agent. It appears as a white crystalline powder with a faint aromatic odor. It is widely recognized for its stability and compatibility with various formulations. As a potent bacteriostat, it is active against Gram-positive and most Gram-negative bacteria, as well as fungi and yeasts.

Our Triclosan is manufactured using advanced purification technologies to ensure low impurity levels, high whiteness, and minimal skin irritation potential. It is extensively used in the daily chemical industry, particularly in personal care products, detergents, and medical disinfectants, providing long-lasting protection against germs.

1 Physicochemical Properties

2 Applications

3 Storage Conditions

4 Safety Precautions

Physicochemical Properties

The following specifications represent our high-purity export standard (USP/BP standards compliant):

Test Item	Specification
Appearance	White crystalline powder
Assay (Purity by HPLC)	≥ 99.0% – 99.5%
Melting Point	56.0°C – 58.0°C
Loss on Drying	≤ 0.1%
Residue on Ignition (Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
4-Chlorophenol	≤ 10 ppm
2,4-Dichlorophenol	≤ 10 ppm
Solubility	Soluble in ethanol, propanol, and propylene glycol; Insoluble in water
pH Value	Neutral to slightly acidic

Applications

Triclosan is a versatile ingredient used in a wide array of consumer and medical products due to its bacteria-fighting capabilities:

Personal Care & Cosmetics:
- Oral Care: Active ingredient in toothpaste and mouthwash to reduce plaque and gingivitis.
- Skin Care: Used in antibacterial facial cleansers, acne treatment creams, and deodorants/antiperspirants to control odor-causing bacteria.
- Hand Hygiene: Key component in liquid hand soaps, bar soaps, and hand sanitizers (non-alcohol based).
Household Daily Chemicals:
- Antibacterial dishwashing liquids.
- Laundry detergents and fabric softeners (for odor control).
- Surface disinfectants and cleaning wipes.
Medical & Institutional:
- Surgical scrubs and preoperative skin preparations.
- Disinfectants for medical instruments.
Functional Materials:
- Used as an antimicrobial additive in textiles, plastics, and polymers to prevent bacterial growth on surfaces.

For a different antimicrobial active that requires separate application and regulatory review, see Chloroxylenol (PCMX).

Storage Conditions

Environment: Store in a cool, dry, and well-ventilated warehouse.
Container: Keep the container tightly sealed when not in use to prevent contamination and oxidation.
Temperature: Store below 40°C. Avoid exposure to extreme heat.
Light Protection: Protect from direct sunlight and strong UV sources.

Safety Precautions

Personal Protection: Wear protective gloves, safety goggles, and a dust mask when handling the raw powder to prevent eye and skin contact.
In Case of Contact:
- Skin: Wash thoroughly with soap and plenty of water.
- Eyes: Rinse cautiously with water for several minutes. Seek medical attention if irritation persists.
Environmental Safety: Triclosan is toxic to aquatic life with long-lasting effects. Do not discharge into lakes, streams, or public sewers without proper treatment. Dispose of waste in accordance with local environmental regulations.

FAQ - Technical & Supply Chain

Q:
What is Triclosan CAS 3380-34-5?

A: Triclosan CAS 3380-34-5 is a polychloro phenoxy phenol with the molecular formula C12H7Cl3O2 and molecular weight 289.55 g/mol. It is used as an antimicrobial active in select personal care, oral care and hard-surface products.
Q:
What are the typical physical and solubility properties of Triclosan?

A: Triclosan is generally a white crystalline powder with a melting point around 55-60 C. It has low water solubility and is more soluble in organic solvents such as ethanol, methanol, acetone and propylene glycol.
Q:
What type of antimicrobial activity does Triclosan provide?

A: Triclosan is a broad-spectrum antibacterial and antifungal agent with activity against Gram-positive bacteria, many Gram-negative bacteria, and some fungi and yeasts. Performance in a finished product depends on concentration, formulation and the target microorganism.
Q:
In which applications is Triclosan commonly used?

A: It is used in personal care products, oral care products, detergents and medical or institutional disinfectants where local regulations permit. Some consumer wash and food-contact uses are restricted or prohibited in certain markets, so formulators should verify the end-use status.
Q:
What quality and storage points are important for Triclosan?

A: High-purity grades are typically controlled for assay, melting point, loss on drying, ash, heavy metals and chlorophenol impurities. Store the material sealed in a cool, dry area and avoid conditions that could cause clumping or contamination.

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