What is Sodium Lauroyl Isethionate CAS 7381-01-3?

Sodium Lauroyl Isethionate, or SLI, CAS 7381-01-3, is a mild anionic surfactant derived from lauric acid and isethionic acid. Its molecular formula is C14H27NaO5S, its EINECS number is 230-949-8, and it is also known as sodium lauryl isethionate or Igepon A.

How does Sodium Lauroyl Isethionate differ from Sodium Cocoyl Isethionate?

SLI is lauric/C12 based, giving it a more uniform molecular profile and consistent melting/solubility behavior. Sodium Cocoyl Isethionate is derived from coconut fatty acids, so it contains a broader distribution of chain lengths and can behave somewhat differently in formulation.

Is Sodium Lauroyl Isethionate suitable for clear liquid body wash?

SLI has limited cold-water solubility and can crystallize or create an opaque/pearlescent appearance, so it is better suited to creamy body washes, syndet bars, and opaque cleansers. For clear systems it normally needs heating, co-surfactants, or careful concentration control.

Why is Sodium Lauroyl Isethionate used in syndet bars?

It gives syndet bars a dense, creamy, stable lather and helps them retain shape while being less irritating than traditional soap-based bars. It also performs well in hard water without forming the soap scum that ordinary soap can leave.

What pH range works best with Sodium Lauroyl Isethionate?

Formulators usually work near neutral to mildly acidic pH, with typical 10% aqueous solution values around 4.7-7.0 depending on grade and test method. This range helps preserve the mildness and foam quality of SLI-based cleansers.

What personal care applications are most suitable for SLI?

SLI is commonly used in facial cleansers, baby washes, sensitive-skin body washes, shampoo bars, and other premium sulfate-free cleansing products where low irritation, creamy foam, and a soft after-feel are priorities.

Sodium Lauroyl Isethionate SLI CAS 7381-01-3

Sodium Lauroyl Isethionate, also called SLI or sodium lauryl isethionate, CAS 7381-01-3, is a mild anionic surfactant supplied as a cosmetic raw material. Confirm the required grade and specification, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 7381-01-3
Synonyms: Sodium 2-(dodecanoyloxy)ethanesulfonate, Dodecanoic acid 2-sulfoethyl ester sodium salt, Isethionic acid lauroyl ester sodium salt, SLI surfactant, Sodium lauryl isethionate
Einecs: 230-949-8
Molecular Formula: C₁₄H₂₇NaO₅S
Grade: Cosmetic Raw Materials
Package: 25kg/bag (Plastic woven bag with PE liner) or 500kg/1000kg Jumbo Bag.

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Product Description

Sodium Lauroyl Isethionate CAS 7381-01-3 is a mild anionic surfactant derived from lauric acid and isethionic acid, also known as SLI, with molecular formula C14H27NaO5S, molecular weight about 330.42 and EINECS 230-949-8.

Synonyms: Sodium 2-(dodecanoyloxy)ethanesulfonate; Dodecanoic acid 2-sulfoethyl ester sodium salt; Isethionic acid lauroyl ester sodium salt; SLI surfactant; Sodium lauryl isethionate.

CAS: 7381-01-3.

It has the molecular formula C14H27NaO5S and a molecular weight of about 330.42 g/mol.

It appears as a white to off-white powder, flakes or prills.

A typical specification includes active matter of about 78–85% and a 10% aqueous solution pH of about 4.7–7.0.

It has limited cold-water solubility and tends to give a creamy or pearlescent rather than clear appearance.

In syndet bars it produces a dense, creamy, stable lather and helps the bar retain its shape.

It is less irritating than traditional soap-based bars, making it suitable for sensitive skin.

It is commonly used in facial cleansers, baby washes, sensitive-skin body washes, shampoo bars and premium sulfate-free cleansers.

Compared with sodium cocoyl isethionate, SLI is C12-based with a more uniform molecular profile and consistent behavior.

For clear liquid systems it is less suitable; creamy or pearlescent formats are preferred.

Store in a cool, dry, well-ventilated area in tightly closed containers to prevent moisture pickup and caking.

Keep away from strong oxidizers and excessive heat.

Confirm appearance, active matter, pH, moisture, heavy metals, microbial limits and residual solvent limits as required.

Use dust masks or respirators and eye protection during handling, and wash skin contact with soap and water.

Confirm packaging with the requested quantity and destination requirements.

The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.

For an RFQ, state the intended use, required grade and specification, quantity, packaging, destination and document needs.

FAQ - Technical & Supply Chain

Q:
What is Sodium Lauroyl Isethionate CAS 7381-01-3?

A: Sodium Lauroyl Isethionate, or SLI, CAS 7381-01-3, is a mild anionic surfactant derived from lauric acid and isethionic acid. Its molecular formula is C14H27NaO5S, its EINECS number is 230-949-8, and it is also known as sodium lauryl isethionate or Igepon A.
Q:
How does Sodium Lauroyl Isethionate differ from Sodium Cocoyl Isethionate?

A: SLI is lauric/C12 based, giving it a more uniform molecular profile and consistent melting/solubility behavior. Sodium Cocoyl Isethionate is derived from coconut fatty acids, so it contains a broader distribution of chain lengths and can behave somewhat differently in formulation.
Q:
Is Sodium Lauroyl Isethionate suitable for clear liquid body wash?

A: SLI has limited cold-water solubility and can crystallize or create an opaque/pearlescent appearance, so it is better suited to creamy body washes, syndet bars, and opaque cleansers. For clear systems it normally needs heating, co-surfactants, or careful concentration control.
Q:
Why is Sodium Lauroyl Isethionate used in syndet bars?

A: It gives syndet bars a dense, creamy, stable lather and helps them retain shape while being less irritating than traditional soap-based bars. It also performs well in hard water without forming the soap scum that ordinary soap can leave.
Q:
What pH range works best with Sodium Lauroyl Isethionate?

A: Formulators usually work near neutral to mildly acidic pH, with typical 10% aqueous solution values around 4.7-7.0 depending on grade and test method. This range helps preserve the mildness and foam quality of SLI-based cleansers.
Q:
What personal care applications are most suitable for SLI?

A: SLI is commonly used in facial cleansers, baby washes, sensitive-skin body washes, shampoo bars, and other premium sulfate-free cleansing products where low irritation, creamy foam, and a soft after-feel are priorities.

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