What is Phenylethyl Resorcinol CAS 85-27-8?

Phenylethyl Resorcinol is a synthetic resorcinol derivative with the formula C14H14O2, INCI name Phenylethyl Resorcinol, and CAS 85-27-8. It is supplied as a white to off-white crystalline powder and is used mainly as a skin-brightening and antioxidant cosmetic active.

Why is Phenylethyl Resorcinol also called 377 or SymWhite 377?

The name 377 comes from the commercial ingredient SymWhite 377. Phenylethyl Resorcinol is the INCI name, while 377 is a widely used trade alias; both refer to the same active CAS 85-27-8.

How does Phenylethyl Resorcinol work in skin-brightening products?

It inhibits tyrosinase and helps reduce melanin formation, which supports brightening and treatment of uneven skin tone. The resorcinol structure can interact with tyrosinase while also providing phenolic antioxidant activity.

What is the typical use level for Phenylethyl Resorcinol in cosmetics?

Cosmetic formulations commonly use it in the range of about 0.1% to 1.0%, with 0.5% frequently cited in clinical or technical references. The final level should be selected through formulation testing and regulatory review.

How should Phenylethyl Resorcinol be incorporated into a formulation?

Because it is essentially insoluble in water, it is normally dissolved in the oil phase or a suitable solvent before emulsification. Gentle heating of the oil phase, followed by confirmation that the powder is fully dissolved, helps avoid undissolved crystals.

What stability precautions are important for Phenylethyl Resorcinol?

The active is sensitive to light and oxidative conditions, so opaque packaging, cool dry storage, and antioxidants in the oil phase are recommended. Exposure to UV or visible light can cause degradation and reddish discoloration.

Phenylethyl Resorcinol CAS 85-27-8

Phenylethyl Resorcinol, also known as SymWhite 377, CAS 85-27-8, is a functional aromatic compound supplied as a cosmetic formulation ingredient for skin care. Confirm the required grade, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 85-27-8
Synonyms: Phenylethyl Resorcinol; 4-(1-Phenylethyl)resorcinol; 4-(1-Phenylethyl)-1,3-benzenediol; 4-(alpha-Methylbenzyl)resorcinol; SymWhite 377
Einecs: 480-070-0
Molecular Formula: C14H14O2
Grade: Cosmetic / industrial supply grade
Package: Standard export packaging or customized packaging

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Product Description

Phenylethyl Resorcinol CAS 85-27-8 is a synthetic resorcinol derivative, with EC 480-070-0 and molecular formula C14H14O2.

Synonyms: 4-(1-Phenylethyl)resorcinol; 4-(1-Phenylethyl)-1,3-benzenediol; 4-(alpha-Methylbenzyl)resorcinol; SymWhite 377.

CAS: 85-27-8.

Molecular formula: C14H14O2.

It is supplied as a white to off-white crystalline powder.

It is used mainly as a skin-brightening and antioxidant cosmetic active.

It is positioned for cosmetic formulation use in skin care products.

It is used in creams, serums, and emulsions.

It inhibits tyrosinase and helps reduce melanin formation.

It is essentially insoluble in water and is normally dissolved in the oil phase or a suitable solvent before emulsification.

Cosmetic formulations commonly use it in the range of about 0.1% to 1.0%.

It is sensitive to light and oxidative conditions, so opaque packaging, cool dry storage, and antioxidants are recommended.

Confirm purity, appearance, particle or crystalline form, and related specifications for the chosen grade.

Store in tightly closed, opaque containers in a cool, dry, well-ventilated area, away from light, moisture, and oxidizing agents.

Use suitable PPE when handling the powder to prevent dust exposure and skin or eye contact.

Confirm packaging suitable for the solid form and order quantity, and follow the current SDS.

Confirm grade, packaging, and specification as required.

The page is an RFQ entry point and does not state stock, price, MOQ, or fixed lead time.

For an RFQ, state the intended application, required grade, quantity, packaging, destination, and document needs.

FAQ - Technical & Supply Chain

Q:
What is Phenylethyl Resorcinol CAS 85-27-8?

A: Phenylethyl Resorcinol is a synthetic resorcinol derivative with the formula C14H14O2, INCI name Phenylethyl Resorcinol, and CAS 85-27-8. It is supplied as a white to off-white crystalline powder and is used mainly as a skin-brightening and antioxidant cosmetic active.
Q:
Why is Phenylethyl Resorcinol also called 377 or SymWhite 377?

A: The name 377 comes from the commercial ingredient SymWhite 377. Phenylethyl Resorcinol is the INCI name, while 377 is a widely used trade alias; both refer to the same active CAS 85-27-8.
Q:
How does Phenylethyl Resorcinol work in skin-brightening products?

A: It inhibits tyrosinase and helps reduce melanin formation, which supports brightening and treatment of uneven skin tone. The resorcinol structure can interact with tyrosinase while also providing phenolic antioxidant activity.
Q:
What is the typical use level for Phenylethyl Resorcinol in cosmetics?

A: Cosmetic formulations commonly use it in the range of about 0.1% to 1.0%, with 0.5% frequently cited in clinical or technical references. The final level should be selected through formulation testing and regulatory review.
Q:
How should Phenylethyl Resorcinol be incorporated into a formulation?

A: Because it is essentially insoluble in water, it is normally dissolved in the oil phase or a suitable solvent before emulsification. Gentle heating of the oil phase, followed by confirmation that the powder is fully dissolved, helps avoid undissolved crystals.
Q:
What stability precautions are important for Phenylethyl Resorcinol?

A: The active is sensitive to light and oxidative conditions, so opaque packaging, cool dry storage, and antioxidants in the oil phase are recommended. Exposure to UV or visible light can cause degradation and reddish discoloration.

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