Why is Glyoxylic Acid supplied as a 50% aqueous solution?

Commercial glyoxylic acid is usually handled as a water solution because the anhydrous material is difficult to isolate and keep stable. The 50% solution form is easier to feed into reactors, reduces handling risk, and is suitable for downstream synthesis while still providing a defined active content.

What are the main industrial uses of Glyoxylic Acid?

Glyoxylic Acid is a versatile C2 building block used to make vanillin and ethyl vanillin, heliotropin, allantoin, and pharmaceutical intermediates. It is also used in selected agrochemical, dye, and fine-chemical synthesis routes.

Why is low glyoxal content important in Glyoxylic Acid?

Glyoxal is an unwanted residue that can interfere with downstream reactions such as allantoin and vanillin synthesis and can affect color stability. Low-glyoxal material is therefore preferred for high-purity fragrance, pharmaceutical, and personal-care applications.

How is Glyoxylic Acid used in hair-care products?

Glyoxylic Acid is used as a crosslinking active in some keratin hair-straightening and smoothing treatments. It is positioned as a formaldehyde-free alternative, so controlled glyoxal, nitric acid, oxalic acid, and color values are important for cosmetic-grade material.

How should Glyoxylic Acid solution be stored and handled?

Store it in closed plastic drums or IBC tanks in a cool, dry, ventilated area away from direct sunlight. The solution is miscible with water and alcohol and should be protected from conditions that could promote discoloration or degradation.

Glyoxylic Acid CAS 298-12-4

Glyoxylic Acid, also called oxoacetic acid, CAS 298-12-4, is a water-miscible C2 alpha-keto acid supplied as a 50% aqueous solution in industrial or pharma grade. Confirm the required grade and specification, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 298-12-4
Synonyms: Oxoacetic acid, Formylformic acid, Oxoethanoic acid, alpha-Ketoacetic acid, Glyoxalic acid
Einecs: 206-058-5
Molecular Formula: C₂H₂O₃
Grade: Industrial Grade / Pharma Grade
Package: 25kg/Plastic Drum, 250kg/Plastic Drum, or 1250kg IBC Tank.

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Product Description

Glyoxylic Acid CAS 298-12-4 is a C2 alpha-keto acid, also known as oxoacetic acid or formylformic acid, with molecular formula C2H2O3, molecular weight 74.04 and EINECS number 206-058-5.

Synonyms: Oxoacetic acid; Formylformic acid; Oxoethanoic acid; alpha-Ketoacetic acid; Glyoxalic acid.

CAS: 298-12-4.

It has the molecular formula C2H2O3 and a molecular weight of 74.04 g/mol.

It is supplied as a clear, colorless to pale yellow 50% aqueous solution that is miscible with water and alcohol.

A typical specification includes assay of 50.0 ± 0.5% as glyoxylic acid.

Glyoxal residue is at most 1.0% for the standard grade and at most 0.5% for the high-purity grade.

Nitric acid residue is at most 0.05%, oxalic acid residue at most 1.0%, color at most 50 APHA, and density at 20 °C is 1.33–1.35 g/cm³.

It is a primary raw material for vanillin and ethyl vanillin, and is also used in the synthesis of heliotropin.

It is used to produce allantoin, atenolol and several broad-spectrum antibiotics such as amoxicillin.

It is used as a formaldehyde-free crosslinking active in keratin hair-straightening and smoothing treatments.

It is also used in selected agrochemical, dye and fine-chemical syntheses, and as a chelating agent in industrial cleaning formulations.

The product is acidic, so it must be stored in plastic (PE/PP) or glass-lined containers; avoid prolonged contact with carbon steel or stainless steel.

Store in a cool, ventilated area away from direct sunlight; keeping the solution below 25 °C helps maintain color stability.

Confirm assay, appearance, glyoxal residue, nitric acid residue, oxalic acid residue, color and density limits.

Keep the drum or IBC tightly closed and protect the solution from conditions that could promote discoloration or degradation.

Confirm packaging with the requested quantity and destination requirements.

The page is an RFQ entry point and does not state stock, price, MOQ or fixed lead time.

For an RFQ, state the intended use, required grade and specification, quantity, packaging, destination and document needs.

FAQ - Technical & Supply Chain

Q:
What is Glyoxylic Acid CAS 298-12-4?

A: Glyoxylic Acid CAS 298-12-4 is a C2 alpha-keto acid with molecular formula C2H2O3, molecular weight 74.04, and EINECS number 206-058-5. It is also known as oxoacetic acid or formylformic acid.
Q:
Why is Glyoxylic Acid supplied as a 50% aqueous solution?

A: Commercial glyoxylic acid is usually handled as a water solution because the anhydrous material is difficult to isolate and keep stable. The 50% solution form is easier to feed into reactors, reduces handling risk, and is suitable for downstream synthesis while still providing a defined active content.
Q:
What are the main industrial uses of Glyoxylic Acid?

A: Glyoxylic Acid is a versatile C2 building block used to make vanillin and ethyl vanillin, heliotropin, allantoin, and pharmaceutical intermediates. It is also used in selected agrochemical, dye, and fine-chemical synthesis routes.
Q:
Why is low glyoxal content important in Glyoxylic Acid?

A: Glyoxal is an unwanted residue that can interfere with downstream reactions such as allantoin and vanillin synthesis and can affect color stability. Low-glyoxal material is therefore preferred for high-purity fragrance, pharmaceutical, and personal-care applications.
Q:
How is Glyoxylic Acid used in hair-care products?

A: Glyoxylic Acid is used as a crosslinking active in some keratin hair-straightening and smoothing treatments. It is positioned as a formaldehyde-free alternative, so controlled glyoxal, nitric acid, oxalic acid, and color values are important for cosmetic-grade material.
Q:
How should Glyoxylic Acid solution be stored and handled?

A: Store it in closed plastic drums or IBC tanks in a cool, dry, ventilated area away from direct sunlight. The solution is miscible with water and alcohol and should be protected from conditions that could promote discoloration or degradation.

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