What is Chloroacetamide CAS 79-07-2?

Chloroacetamide is a chlorinated amide with the linear formula ClCH2CONH2, the molecular formula C2H4ClNO, and a molecular weight of 93.51 g/mol. It is used mainly as a reactive intermediate in organic synthesis and specialty chemical production.

What are the key physical properties of Chloroacetamide?

It is normally a white to off-white crystalline solid or powder with a melting point commonly reported around 116-120 °C. Chloroacetamide is soluble in water and ethanol and very slightly soluble in ether, which makes it suitable for both aqueous and polar organic reaction systems.

What is the difference between Chloroacetamide and chloroacetic acid?

Chloroacetamide contains an amide group, while chloroacetic acid contains a carboxylic acid group. Both are chlorinated C2 building blocks, but they differ in reactivity, acidity, solubility, and downstream chemistry, so they are not interchangeable in synthesis routes.

Does Chloroacetamide have more than one crystalline form?

Yes. Technical sources describe more than one crystalline modification, with the alpha form commonly regarded as the stable form. The form obtained can depend on crystallization conditions, so particle appearance and crystalline behavior should be confirmed with the supplier if they affect processing.

What quality parameters should be checked for industrial Chloroacetamide?

The most relevant parameters are assay, appearance, melting range, moisture, residue, and impurity profile. Because it is a reactive chlorinated amide, buyers should specify the required purity and any application-specific limits before confirming a grade for production.

Chloroacetamide CAS 79-07-2

Chloroacetamide, also called 2-chloroacetamide, CAS 79-07-2, is a chlorinated amide supplied as a crystalline solid and positioned as an organic synthesis intermediate and specialty chemical raw material. Confirm the required grade, then request a quotation with COA/TDS/SDS for bulk supply.

CAS: 79-07-2
Synonyms: Chloroacetamide; 2-Chloroacetamide; α-Chloroacetamide; 2-Chloroethanamide; Monochloroacetamide
Einecs: 201-174-2
Molecular Formula: C2H4ClNO
Grade: Industrial / synthesis grade
Package: Standard export bag or drum packaging

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Product Description

Chloroacetamide CAS 79-07-2 is a chlorinated amide compound, with EC 201-174-2 and molecular formula C2H4ClNO.

Synonyms: 2-Chloroacetamide; alpha-Chloroacetamide; 2-Chloroethanamide; Monochloroacetamide.

CAS: 79-07-2.

Molecular formula: C2H4ClNO.

It has a molecular weight of about 93.51 g/mol.

It is supplied as a white to off-white crystalline solid or powder.

It has a melting point commonly reported around 116-120 C and is soluble in water and ethanol.

It is positioned as an organic synthesis intermediate and specialty chemical raw material.

It is used to prepare chloroacetonitrile and other downstream organic compounds.

It can serve as a reagent for carboxamidomethyl ester protecting groups in peptide synthesis.

It is evaluated in pharmaceutical intermediate routes and heterocyclic synthesis.

It differs from chloroacetic acid by containing an amide group rather than a carboxylic acid group.

Confirm the required grade, assay, appearance, melting range, moisture, residue, and impurity profile for the chosen grade.

Store in tightly closed containers in a cool, dry, well-ventilated area, away from moisture and direct sunlight.

Use suitable PPE when handling the solid to prevent dust exposure and skin or eye contact.

Confirm packaging suitable for the solid form and order quantity, and follow the current SDS.

Confirm grade, packaging, and specification as required.

The page is an RFQ entry point and does not state stock, price, MOQ, or fixed lead time.

For an RFQ, state the intended application, required grade, quantity, packaging, destination, and document needs.

FAQ - Technical & Supply Chain

Q:
What is Chloroacetamide CAS 79-07-2?

A: Chloroacetamide is a chlorinated amide with the linear formula ClCH2CONH2, the molecular formula C2H4ClNO, and a molecular weight of 93.51 g/mol. It is used mainly as a reactive intermediate in organic synthesis and specialty chemical production.
Q:
What are the key physical properties of Chloroacetamide?

A: It is normally a white to off-white crystalline solid or powder with a melting point commonly reported around 116-120 °C. Chloroacetamide is soluble in water and ethanol and very slightly soluble in ether, which makes it suitable for both aqueous and polar organic reaction systems.
Q:
What is the difference between Chloroacetamide and chloroacetic acid?

A: Chloroacetamide contains an amide group, while chloroacetic acid contains a carboxylic acid group. Both are chlorinated C2 building blocks, but they differ in reactivity, acidity, solubility, and downstream chemistry, so they are not interchangeable in synthesis routes.
Q:
What are the main synthesis applications of Chloroacetamide?

A: Chloroacetamide is used to prepare chloroacetonitrile and other downstream organic compounds, and it can serve as a reagent for carboxamidomethyl ester protecting groups in peptide synthesis. It is also evaluated in pharmaceutical intermediate routes, heterocyclic synthesis, and selected specialty chemical processes.
Q:
Does Chloroacetamide have more than one crystalline form?

A: Yes. Technical sources describe more than one crystalline modification, with the alpha form commonly regarded as the stable form. The form obtained can depend on crystallization conditions, so particle appearance and crystalline behavior should be confirmed with the supplier if they affect processing.
Q:
What quality parameters should be checked for industrial Chloroacetamide?

A: The most relevant parameters are assay, appearance, melting range, moisture, residue, and impurity profile. Because it is a reactive chlorinated amide, buyers should specify the required purity and any application-specific limits before confirming a grade for production.

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